Detailed information NTG1127350

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: FGK96_RS06675
• Genome accession: NZ_LR594036
• Coordinates: 1396742..1397458 (-)
• Length: 238 a.a.
• NCBI ID: WP_138082471.1
• Uniprot ID: A0A4U9Z8F1
• Organism: Streptococcus porcinus strain NCTC10710
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1391742..1402458

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGK96_RS06650 (NCTC10710_01378)	pstB	1391900..1392652 (-)	753	WP_138082465.1	phosphate ABC transporter ATP-binding protein PstB	-
FGK96_RS06655 (NCTC10710_01379)	pstA	1392655..1393470 (-)	816	WP_093959089.1	phosphate ABC transporter permease PstA	-
FGK96_RS06660 (NCTC10710_01380)	pstC	1393463..1394326 (-)	864	WP_138082467.1	phosphate ABC transporter permease subunit PstC	-
FGK96_RS06665 (NCTC10710_01381)	-	1394390..1395267 (-)	878	Protein_1277	substrate-binding domain-containing protein	-
FGK96_RS06670 (NCTC10710_01383)	pnpS	1395424..1396758 (-)	1335	WP_138082469.1	two-component system histidine kinase PnpS	-
FGK96_RS06675 (NCTC10710_01384)	vicR	1396742..1397458 (-)	717	WP_138082471.1	response regulator transcription factor	Regulator
FGK96_RS06680 (NCTC10710_01385)	-	1397539..1397994 (-)	456	Protein_1280	cupin domain-containing protein	-
FGK96_RS06685 (NCTC10710_01386)	-	1398093..1398477 (-)	385	Protein_1281	VOC family protein	-
FGK96_RS10495 (NCTC10710_01387)	-	1398672..1398833 (+)	162	WP_172601610.1	SPJ_0845 family protein	-
FGK96_RS06690 (NCTC10710_01388)	-	1398882..1399790 (+)	909	WP_093959095.1	permease	-
FGK96_RS06695 (NCTC10710_01389)	-	1399787..1400602 (+)	816	WP_138082475.1	TIGR03943 family putative permease subunit	-
FGK96_RS06700 (NCTC10710_01390)	-	1400716..1402080 (+)	1365	WP_138082477.1	MFS transporter	-

Sequence

Protein

• Length: 238 a.a.
• Molecular weight: 28137.45 Da
• Isoelectric Point: 5.3069

>NTDB_id=1127350 FGK96_RS06675 WP_138082471.1 1396742..1397458(-) (vicR) [Streptococcus porcinus strain NCTC10710]
MKKQVLLVDDEEHILRLLDYHLNKEGYETELVEDGRTALKLAESEHYDFILLDIMLPQLDGIEVCKRIRAKGIQTPIMMV
SAKSDEFDKVLALELGADDYMTKPFSPRELVARLKAILRRIDKEDSSERFAEEFWSFDDLVIYPERHEIYKDKILLNVTP
KEFELLLYLVKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLRDKIEDDPKNPKFIKTIRGYGYKFKGKQDEEKS

Nucleotide

• Length: 717 bp

>NTDB_id=1127350 FGK96_RS06675 WP_138082471.1 1396742..1397458(-) (vicR) [Streptococcus porcinus strain NCTC10710]
ATGAAAAAACAGGTATTATTGGTTGACGATGAAGAACATATTTTACGACTACTTGATTACCATTTAAACAAAGAAGGTTA
CGAAACAGAATTAGTCGAGGATGGTCGTACAGCACTAAAACTAGCAGAGTCAGAACACTATGATTTTATATTACTTGATA
TTATGTTACCTCAGTTAGATGGCATTGAAGTTTGTAAGAGAATCAGAGCTAAAGGTATTCAGACACCAATTATGATGGTC
TCAGCTAAGAGTGACGAATTTGATAAGGTGCTTGCTTTAGAGTTGGGTGCTGATGATTACATGACAAAGCCATTTAGTCC
AAGGGAGCTTGTAGCTCGCTTGAAAGCTATCTTACGTCGAATTGATAAAGAAGACAGTAGTGAGAGATTTGCAGAAGAGT
TTTGGAGTTTTGATGATCTTGTTATTTACCCTGAACGTCATGAAATCTATAAAGATAAGATTCTTTTAAATGTGACCCCT
AAAGAATTTGAATTGTTGCTTTATTTGGTAAAACACCCAAACATGACTTTAACTCGAGAAAGATTATTAGAGCGTATTTG
GGGTTACGACTTTGGTCAAGAAACGCGATTAGTAGATGTTCATATTGGTAAATTACGAGATAAGATAGAAGATGATCCCA
AAAATCCTAAATTCATCAAAACCATTCGTGGTTATGGCTATAAATTTAAGGGGAAGCAGGATGAAGAAAAATCTTAA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (156-229)

• Response regulator receiver domain (Response_reg) (5-114)

3D structure

• AlphaFold DB: A0A4U9Z8F1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	48.936	98.739	0.483
micA	Streptococcus pneumoniae Cp1015	46.809	98.739	0.462
covR	Lactococcus lactis subsp. lactis strain DGCC12653	41.81	97.479	0.408
covR	Streptococcus salivarius strain HSISS4	38.362	97.479	0.374