Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   FGL04_RS07840 Genome accession   NZ_LR594035
Coordinates   1523987..1524742 (-) Length   251 a.a.
NCBI ID   WP_138068797.1    Uniprot ID   A0A4U9Z382
Organism   Streptococcus pseudoporcinus strain NCTC5385     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1518987..1529742
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL04_RS07820 (NCTC5385_01705) - 1519328..1520554 (-) 1227 WP_138068793.1 cysteine desulfurase -
  FGL04_RS07825 (NCTC5385_01706) sufD 1520570..1521835 (-) 1266 WP_138068794.1 Fe-S cluster assembly protein SufD -
  FGL04_RS07830 (NCTC5385_01707) sufC 1521930..1522700 (-) 771 WP_138068795.1 Fe-S cluster assembly ATPase SufC -
  FGL04_RS07835 (NCTC5385_01708) - 1522826..1523980 (-) 1155 WP_138068796.1 glycosyltransferase family 4 protein -
  FGL04_RS07840 (NCTC5385_01709) mecA 1523987..1524742 (-) 756 WP_138068797.1 adaptor protein MecA Regulator
  FGL04_RS07845 (NCTC5385_01710) - 1524856..1525695 (-) 840 WP_007893599.1 undecaprenyl-diphosphate phosphatase -
  FGL04_RS07850 (NCTC5385_01711) - 1525820..1527724 (-) 1905 WP_138068798.1 DUF2207 domain-containing protein -
  FGL04_RS07855 (NCTC5385_01712) - 1527914..1529485 (+) 1572 WP_138068799.1 ABC transporter substrate-binding protein/permease -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 29382.31 Da        Isoelectric Point: 4.1556

>NTDB_id=1127311 FGL04_RS07840 WP_138068797.1 1523987..1524742(-) (mecA) [Streptococcus pseudoporcinus strain NCTC5385]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYTVMDELDLPENFKDSGMLSFRVTPRKDRLDVFVTKSEL
SKEIDFEDLTDLGDVSQMTPEDFFKTIEKNMIEKGYVNAHEKLEKIEEMLEEAVEANQTQTTVSDETTQTVEPMDYVHYV
FDFLTIEEVISFSKIVNFPIEASELYKETNRYHLTILLDIQNQPAYFANIMYARLIEHALPGSRTRAYLQEHATLLIEDQ
AVEQLKKIELV

Nucleotide


Download         Length: 756 bp        

>NTDB_id=1127311 FGL04_RS07840 WP_138068797.1 1523987..1524742(-) (mecA) [Streptococcus pseudoporcinus strain NCTC5385]
ATGGAAATGAAACAAATTAGTGAAACGACACTAAAGATAACAATCAGTATGGATGATTTGGAAGAAAGAGGCATGGAATT
AAAGGATTTTTTAATTCCTCAGGAAAAAACAGAAGAATTTTTCTATACTGTTATGGATGAACTGGATTTACCTGAAAACT
TTAAAGATAGTGGGATGTTAAGTTTTAGGGTTACCCCACGTAAAGATCGTTTAGATGTTTTTGTTACGAAGTCAGAGTTA
TCTAAAGAGATTGATTTTGAGGATTTGACTGATCTAGGAGATGTTTCTCAGATGACGCCCGAAGATTTTTTTAAAACAAT
TGAAAAAAATATGATCGAAAAGGGCTATGTCAACGCTCATGAAAAATTAGAAAAAATTGAAGAAATGTTAGAAGAGGCAG
TTGAGGCAAATCAAACTCAAACGACAGTGAGTGATGAAACTACCCAGACTGTTGAACCGATGGACTACGTCCATTATGTT
TTTGATTTTTTAACTATAGAAGAAGTCATTAGCTTTTCTAAAATAGTCAACTTTCCAATTGAAGCTTCAGAGCTTTACAA
GGAAACGAATCGTTATCACCTGACAATCTTACTTGATATTCAAAATCAGCCAGCCTACTTTGCTAATATTATGTACGCCC
GTCTAATTGAACATGCATTACCTGGTTCAAGGACACGTGCTTATTTGCAGGAGCATGCAACCTTACTGATCGAAGATCAA
GCAGTAGAACAGCTGAAAAAGATTGAATTGGTGTGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4U9Z382

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

61.29

98.805

0.606
  mecA Streptococcus thermophilus LMD-9

56.68

98.406

0.558
  mecA Streptococcus thermophilus LMG 18311

56.275

98.406

0.554
  mecA Streptococcus pneumoniae TIGR4

45.817

100

0.458
  mecA Streptococcus pneumoniae Rx1

45.418

100

0.454
  mecA Streptococcus pneumoniae D39

45.418

100

0.454
  mecA Streptococcus pneumoniae R6

45.418

100

0.454

Multiple sequence alignment