Detailed information NTG1127272

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: FGL04_RS00245
• Genome accession: NZ_LR594035
• Coordinates: 38023..38928 (+)
• Length: 301 a.a.
• NCBI ID: WP_138067814.1
• Uniprot ID: A0A4V6KZK9
• Organism: Streptococcus pseudoporcinus strain NCTC5385
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 33023..43928

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL04_RS00225 (NCTC5385_00044)	-	33416..34507 (-)	1092	WP_138067812.1	CHAP domain-containing protein	-
FGL04_RS00230 (NCTC5385_00045)	-	34628..35244 (-)	617	Protein_24	hypothetical protein	-
FGL04_RS10645	-	35976..36197 (+)	222	WP_416236981.1	hypothetical protein	-
FGL04_RS00235 (NCTC5385_00047)	-	36161..36589 (+)	429	WP_007892002.1	GNAT family N-acetyltransferase	-
FGL04_RS00240 (NCTC5385_00048)	purB	36628..37920 (+)	1293	WP_138067813.1	adenylosuccinate lyase	-
FGL04_RS00245 (NCTC5385_00049)	comR	38023..38928 (+)	906	WP_138067814.1	helix-turn-helix transcriptional regulator	Regulator
FGL04_RS10855 (NCTC5385_00050)	-	39001..39099 (+)	99	WP_217284603.1	quorum-sensing system DWW-type pheromone	-
FGL04_RS00250 (NCTC5385_00051)	ruvB	39131..40129 (+)	999	WP_138067815.1	Holliday junction branch migration DNA helicase RuvB	-
FGL04_RS00255 (NCTC5385_00052)	-	40405..40848 (+)	444	WP_138067816.1	low molecular weight protein-tyrosine-phosphatase	-
FGL04_RS00260 (NCTC5385_00053)	-	40857..41258 (+)	402	WP_138067817.1	hypothetical protein	-
FGL04_RS00265 (NCTC5385_00054)	-	41255..43033 (+)	1779	WP_138067818.1	acyltransferase family protein	-

Sequence

Protein

• Length: 301 a.a.
• Molecular weight: 35986.80 Da
• Isoelectric Point: 7.9429

>NTDB_id=1127272 FGL04_RS00245 WP_138067814.1 38023..38928(+) (comR) [Streptococcus pseudoporcinus strain NCTC5385]
MKKLGKKIQKLRLDKSLTRETNCGDESELSIRQLARIEKEQSIPSLSKVLFIAKKLDLPVIELINPECLVLPKRYKELKY
LILRRPTYMNDQNLVDREAQFDEIFEDYYATLPEEEQLIIDLLQSRFDVYQSGDTNYGKELLREYISQIRKKKSYALNDI
FLIDLYLTCGMVSNFKEELFDKGNFDCFTNKLVLLEDKLELKDLFLLNNVLLTSIAVGISIKEYQKTRILLDVCRRIMTI
TQDFQRMPIYYMYEWKYTLFYMKDSQKAYYYYRQSLIFARTLTDSYLVNRLKTSWELDNQS

Nucleotide

• Length: 906 bp

>NTDB_id=1127272 FGL04_RS00245 WP_138067814.1 38023..38928(+) (comR) [Streptococcus pseudoporcinus strain NCTC5385]
ATGAAAAAACTTGGGAAAAAGATTCAAAAATTGAGGTTAGACAAGAGCCTGACTCGTGAAACGAATTGTGGAGATGAGTC
AGAATTATCAATTCGACAGCTAGCTCGTATTGAAAAAGAGCAATCTATTCCTAGTTTATCTAAAGTCTTATTTATTGCAA
AAAAATTAGATTTACCTGTTATTGAACTTATTAATCCAGAATGTTTGGTTCTACCAAAACGTTATAAGGAACTTAAATAT
TTGATTCTTAGGCGACCAACCTACATGAATGATCAAAATTTAGTGGATCGCGAAGCTCAGTTTGATGAAATATTTGAAGA
TTATTACGCGACTTTACCTGAAGAAGAGCAACTAATTATTGATTTATTACAGTCTCGGTTTGATGTCTACCAAAGTGGTG
ATACTAATTATGGTAAAGAATTACTCCGTGAGTATATCAGCCAAATTCGTAAGAAAAAGAGTTACGCTTTAAATGATATT
TTTTTAATCGATCTTTACTTAACTTGTGGAATGGTTTCAAATTTCAAAGAAGAATTATTTGATAAGGGAAATTTTGATTG
TTTTACTAATAAATTAGTCCTTTTGGAAGATAAGTTAGAGTTAAAAGATCTCTTTTTACTAAACAACGTCCTTCTCACTT
CCATTGCCGTAGGGATTAGTATTAAAGAATATCAGAAAACAAGGATACTTTTGGATGTTTGTCGACGGATTATGACGATT
ACCCAAGACTTTCAGCGTATGCCGATTTACTATATGTACGAATGGAAATACACTTTATTTTATATGAAGGACTCCCAAAA
GGCTTATTATTACTATCGTCAATCCTTAATATTTGCACGGACACTAACAGATAGTTATCTTGTTAATCGTTTAAAAACAA
GTTGGGAATTAGATAATCAATCGTAA

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (72-295)

3D structure

• AlphaFold DB: A0A4V6KZK9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS315	50.336	99.003	0.498
comR	Streptococcus pyogenes MGAS8232	45.515	100	0.455
comR	Streptococcus mutans UA159	43.854	100	0.439
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	45.172	96.346	0.435
comR	Streptococcus suis P1/7	38.079	100	0.382
comR	Streptococcus suis 05ZYH33	38.079	100	0.382