Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   FGK99_RS07635 Genome accession   NZ_LR594033
Coordinates   1615929..1618085 (+) Length   718 a.a.
NCBI ID   WP_138119671.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC4675     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1610929..1623085
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK99_RS10175 (NCTC4675_01540) - 1610962..1611150 (-) 189 WP_231142699.1 hypothetical protein -
  FGK99_RS07600 (NCTC4675_01541) - 1611812..1612015 (-) 204 WP_012516109.1 Blp family class II bacteriocin -
  FGK99_RS07605 (NCTC4675_01542) - 1612032..1612286 (-) 255 WP_111692691.1 Blp family class II bacteriocin -
  FGK99_RS07610 (NCTC4675_01543) - 1612440..1612736 (-) 297 WP_012516111.1 bacteriocin immunity protein -
  FGK99_RS07615 (NCTC4675_01544) - 1612736..1612954 (-) 219 WP_138119667.1 leucocin A/sakacin P family class II bacteriocin -
  FGK99_RS07620 - 1613265..1614613 (+) 1349 WP_138119669.1 IS3 family transposase -
  FGK99_RS07625 (NCTC4675_01547) - 1615119..1615415 (-) 297 WP_012516113.1 bacteriocin immunity protein -
  FGK99_RS07630 (NCTC4675_01548) - 1615422..1615670 (-) 249 WP_012677516.1 garvicin Q family class II bacteriocin -
  FGK99_RS07635 (NCTC4675_01549) comA/nlmT 1615929..1618085 (+) 2157 WP_138119671.1 peptide cleavage/export ABC transporter Regulator
  FGK99_RS07640 (NCTC4675_01550) - 1618096..1619454 (+) 1359 WP_138119673.1 bacteriocin secretion accessory protein -
  FGK99_RS07645 (NCTC4675_01551) - 1619554..1619688 (+) 135 WP_138119674.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  FGK99_RS10255 (NCTC4675_01552) - 1619807..1621141 (-) 1335 WP_043040994.1 sensor histidine kinase -
  FGK99_RS07655 (NCTC4675_01553) comE/blpR 1621141..1621890 (-) 750 WP_111690344.1 LytR/AlgR family response regulator transcription factor Regulator
  FGK99_RS07660 (NCTC4675_01554) - 1622524..1622718 (-) 195 WP_038674052.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  FGK99_RS07665 (NCTC4675_01555) - 1622735..1622992 (-) 258 WP_043030068.1 Blp family class II bacteriocin -

Sequence

Protein


Download         Length: 718 a.a.        Molecular weight: 80631.88 Da        Isoelectric Point: 8.0723

>NTDB_id=1127190 FGK99_RS07635 WP_138119671.1 1615929..1618085(+) (comA/nlmT) [Streptococcus equi subsp. zooepidemicus strain NCTC4675]
MTLFYKRTFVPQIDARDCGVAALASIARYYGSDYSLAHLRELAKTNKEGTTALGIVMAAKEMGFETRPIQADMTLFDMAD
VPYPLIVHVNKEGKLQHYYVVYKSKKDYLIIGDPDPMVKVTKMSKERFASEWTGVTICLAPKPNYKPHKDQKNGLLGFFP
LIFKQRALIFYIVLASVLVTVINIAGSYYLQGILDEYIPNQLKSTLGIVSIGLIITYILQQLMSFSRDYLLTVLSQRLTI
DVILSYIRHIFELPMSFFATRRTGEVTSRFTDANSIIDALASTILSLFLDLSILAIVGSVLLVQNSRLFLLSLISIPVYT
IIICAFIKPFEQMNHDVMQSNAMLSSAIIEDINGIETIKSLTSEENRYQKIDSDFVDYLDKSFRLSKYTILQATLKQGAQ
LILNIIILWFGAQLVINGRISIGQLITFNTLLAYFTTPLENIINLQTKLQAAKVANNRLNEVYLVESEFKASQALYDLSL
LQGDIQFEAVSYRYGFGKDTLSDITLTIKQGAKVTLVGVSGSGKTTLAKMLVNFFEPYKGRITINQNDLKTIDKKNLRQY
INYLPQQAYIFNGSILENLTLGAKQGISQEDILKACEIADIRHDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKA
PILVLDEATSGLDILTEKKIIDRLMNMTDKTIIFVAHRLSIAERTDQIVVLNQGQIIETGSHQELMKQGGFYYHLFSE

Nucleotide


Download         Length: 2157 bp        

>NTDB_id=1127190 FGK99_RS07635 WP_138119671.1 1615929..1618085(+) (comA/nlmT) [Streptococcus equi subsp. zooepidemicus strain NCTC4675]
ATGACACTCTTTTATAAAAGAACCTTTGTACCACAAATAGATGCCAGAGATTGTGGCGTAGCTGCTCTAGCTTCGATCGC
AAGGTATTATGGTTCAGATTATTCATTAGCTCATTTGAGAGAATTAGCAAAGACCAATAAGGAAGGGACAACAGCCCTCG
GTATTGTCATGGCTGCTAAGGAAATGGGATTTGAAACCAGACCCATTCAAGCGGATATGACCCTCTTTGACATGGCAGAC
GTGCCCTATCCATTGATCGTCCATGTCAATAAAGAAGGAAAGCTACAGCACTACTATGTGGTCTACAAATCTAAAAAAGA
CTATCTTATCATTGGTGATCCCGATCCAATGGTCAAGGTCACAAAAATGTCCAAGGAACGCTTTGCTTCTGAATGGACAG
GTGTCACCATATGTCTTGCTCCTAAGCCAAATTATAAACCACATAAAGACCAAAAAAATGGACTATTAGGCTTCTTTCCG
CTTATTTTTAAACAGCGAGCCCTTATTTTTTATATCGTGTTAGCTTCTGTCTTGGTAACAGTCATTAATATTGCTGGTTC
ATACTATCTCCAAGGGATTTTAGACGAGTATATTCCAAATCAGCTGAAATCTACCTTAGGGATTGTATCAATTGGTCTCA
TCATTACCTATATACTCCAGCAGCTAATGAGCTTTTCTAGAGATTATCTTTTAACTGTCCTTAGCCAACGTCTTACGATT
GATGTGATCCTGTCCTATATCCGCCATATTTTCGAATTGCCGATGTCCTTTTTTGCAACACGTCGAACAGGTGAGGTAAC
CTCGCGCTTTACAGATGCTAACTCTATCATTGACGCACTCGCTTCAACCATTTTATCCCTCTTTCTAGACCTCTCTATAT
TAGCTATTGTCGGAAGTGTTCTTTTGGTGCAAAATAGCAGGCTTTTTCTGCTATCTCTGATTTCTATTCCAGTATATACC
ATTATCATATGTGCCTTTATAAAGCCGTTTGAACAAATGAATCATGATGTGATGCAAAGCAATGCCATGCTAAGCTCTGC
TATTATCGAAGATATCAACGGGATCGAAACCATAAAATCACTAACCAGTGAAGAAAACCGTTACCAAAAAATTGACAGCG
ACTTTGTGGATTACCTAGATAAGTCCTTTAGGCTTAGTAAATATACCATCTTACAAGCCACACTTAAGCAAGGAGCGCAG
CTAATTCTGAATATCATCATTCTTTGGTTTGGGGCTCAACTGGTTATTAATGGTAGGATTTCAATCGGGCAGTTAATTAC
CTTTAACACACTTCTTGCCTATTTTACAACCCCTTTAGAAAATATCATTAATCTTCAAACTAAGCTCCAAGCAGCTAAGG
TTGCCAACAATCGTCTCAATGAGGTCTATCTTGTAGAGTCCGAATTTAAAGCCTCGCAAGCCTTATACGATTTATCGCTT
TTACAGGGTGACATTCAGTTTGAAGCTGTTTCCTATAGGTATGGCTTTGGCAAGGATACATTATCAGATATTACATTAAC
CATTAAACAGGGAGCAAAAGTAACCCTTGTTGGTGTCAGCGGCTCAGGAAAAACAACCCTAGCCAAGATGCTCGTCAATT
TCTTTGAGCCTTATAAGGGACGTATAACCATCAACCAAAACGATCTCAAGACCATTGATAAAAAGAATCTTCGACAATAC
ATCAACTACCTTCCACAACAAGCCTATATCTTTAATGGATCTATCTTAGAAAATCTAACCTTGGGAGCCAAGCAAGGCAT
CAGCCAGGAAGACATTCTTAAAGCCTGTGAGATTGCTGACATTCGTCACGACATCGAGCAAATGCCAATGGGATACCAAA
CCGAGCTCTCTGATGGAGCTGGCTTATCTGGCGGACAAAAACAGAGAATTGCACTGGCTAGAGCATTATTAACCAAAGCT
CCTATATTAGTTCTTGATGAAGCAACCAGCGGACTTGACATACTGACAGAAAAGAAAATCATTGACCGTCTCATGAACAT
GACAGACAAAACGATTATTTTCGTTGCCCACCGGCTTAGTATCGCAGAGCGCACTGATCAGATTGTTGTTCTTAATCAAG
GGCAAATCATTGAAACAGGCAGCCACCAGGAATTAATGAAACAAGGTGGATTTTATTACCACCTATTTAGTGAATAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(169-439)

Peptidase C39 family (Peptidase_C39)

(8-143)

ABC transporter (ABC_tran)

(501-650)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

70.572

99.861

0.705
  comA Streptococcus mitis SK321

67.461

99.304

0.67
  comA Streptococcus mitis NCTC 12261

67.181

99.304

0.667
  comA Streptococcus pneumoniae Rx1

66.76

99.304

0.663
  comA Streptococcus pneumoniae D39

66.76

99.304

0.663
  comA Streptococcus pneumoniae R6

66.76

99.304

0.663
  comA Streptococcus pneumoniae TIGR4

66.48

99.304

0.66
  comA Streptococcus gordonii str. Challis substr. CH1

65.077

99.304

0.646

Multiple sequence alignment