Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   FGK99_RS04850 Genome accession   NZ_LR594033
Coordinates   1021563..1022237 (+) Length   224 a.a.
NCBI ID   WP_021320708.1    Uniprot ID   A0AAW3GMV5
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC4675     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1016563..1027237
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK99_RS04835 (NCTC4675_00977) pstB 1016890..1017648 (+) 759 WP_012678019.1 phosphate ABC transporter ATP-binding protein PstB -
  FGK99_RS04840 (NCTC4675_00978) phoU 1017719..1018372 (+) 654 WP_012678018.1 phosphate signaling complex protein PhoU -
  FGK99_RS04845 (NCTC4675_00979) - 1018607..1021144 (+) 2538 WP_138119270.1 M1 family metallopeptidase -
  FGK99_RS04850 (NCTC4675_00980) ciaR 1021563..1022237 (+) 675 WP_021320708.1 response regulator transcription factor Regulator
  FGK99_RS04855 (NCTC4675_00981) ciaH 1022230..1023540 (+) 1311 WP_138119272.1 sensor histidine kinase Regulator
  FGK99_RS04860 (NCTC4675_00982) - 1023951..1024364 (+) 414 WP_138119274.1 hypothetical protein -
  FGK99_RS04865 (NCTC4675_00983) - 1024590..1025003 (+) 414 WP_012677437.1 hypothetical protein -
  FGK99_RS04870 (NCTC4675_00984) - 1024987..1025241 (+) 255 WP_138119276.1 hypothetical protein -
  FGK99_RS04875 (NCTC4675_00985) - 1025257..1025670 (+) 414 WP_037584331.1 hypothetical protein -
  FGK99_RS04880 (NCTC4675_00986) - 1025670..1026860 (+) 1191 WP_420340943.1 hypothetical protein -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25569.58 Da        Isoelectric Point: 4.5644

>NTDB_id=1127178 FGK99_RS04850 WP_021320708.1 1021563..1022237(+) (ciaR) [Streptococcus equi subsp. zooepidemicus strain NCTC4675]
MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGIYDLILLDLMLPEKDGFQVLKALREKDIKIPVLIMTA
KESIDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRVGKFNDKSLKFGNLTVDTTRKEVQVNGQVIELLGKELDLLIY
ILQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVNHLQTLRSVGYILKANE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1127178 FGK99_RS04850 WP_021320708.1 1021563..1022237(+) (ciaR) [Streptococcus equi subsp. zooepidemicus strain NCTC4675]
ATGATAAAACTATTATTAGTAGAAGACGATTTAAGCTTATCAAATTCCATCTTTGATTTTTTAGATGACTTTGCTGATGT
GACCCAGGTTTTTGATGGCGACGAAGGACTCTATGAGGCAGAAAGCGGCATTTATGATTTGATTCTGTTAGATTTGATGC
TGCCTGAAAAGGATGGCTTTCAAGTGCTAAAGGCCTTACGTGAAAAAGACATCAAAATTCCCGTCTTGATCATGACTGCC
AAAGAAAGCATTGATGACAAGGGACATGGCTTTGAGCTTGGTGCTGATGACTATTTAACCAAGCCCTTTTACCTAGAGGA
ATTAAAAATGCGGATTCAGGCCTTGCTTAAGCGCGTAGGAAAGTTTAATGATAAGAGCCTTAAATTTGGCAACCTGACTG
TAGATACTACCCGTAAAGAGGTACAGGTCAATGGGCAGGTCATAGAGCTATTAGGCAAGGAGCTTGATTTACTAATCTAT
ATCCTTCAAAATCAAAATGTTATTTTGCCAAAGTCACAAATTTTTGATCGTATCTGGGGCTTTGATAGTGATACCACTAT
CTCTGTTGTAGAGGTCTATGTCTCTAAAATCCGTAAGAAGCTTAAGGGGACAGACTTTGTTAATCATCTTCAAACCTTGA
GAAGTGTAGGATATATCTTAAAAGCTAATGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae Rx1

80.543

98.661

0.795
  ciaR Streptococcus pneumoniae D39

80.543

98.661

0.795
  ciaR Streptococcus pneumoniae R6

80.543

98.661

0.795
  ciaR Streptococcus pneumoniae TIGR4

80.543

98.661

0.795
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.865

100

0.397

Multiple sequence alignment