Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   FGK99_RS04855 Genome accession   NZ_LR594033
Coordinates   1022230..1023540 (+) Length   436 a.a.
NCBI ID   WP_138119272.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC4675     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1017230..1028540
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK99_RS04840 (NCTC4675_00978) phoU 1017719..1018372 (+) 654 WP_012678018.1 phosphate signaling complex protein PhoU -
  FGK99_RS04845 (NCTC4675_00979) - 1018607..1021144 (+) 2538 WP_138119270.1 M1 family metallopeptidase -
  FGK99_RS04850 (NCTC4675_00980) ciaR 1021563..1022237 (+) 675 WP_021320708.1 response regulator transcription factor Regulator
  FGK99_RS04855 (NCTC4675_00981) ciaH 1022230..1023540 (+) 1311 WP_138119272.1 sensor histidine kinase Regulator
  FGK99_RS04860 (NCTC4675_00982) - 1023951..1024364 (+) 414 WP_138119274.1 hypothetical protein -
  FGK99_RS04865 (NCTC4675_00983) - 1024590..1025003 (+) 414 WP_012677437.1 hypothetical protein -
  FGK99_RS04870 (NCTC4675_00984) - 1024987..1025241 (+) 255 WP_138119276.1 hypothetical protein -
  FGK99_RS04875 (NCTC4675_00985) - 1025257..1025670 (+) 414 WP_037584331.1 hypothetical protein -
  FGK99_RS04880 (NCTC4675_00986) - 1025670..1026860 (+) 1191 WP_420340943.1 hypothetical protein -
  FGK99_RS04885 (NCTC4675_00987) - 1026857..1027249 (+) 393 WP_138119280.1 hypothetical protein -
  FGK99_RS04890 (NCTC4675_00988) - 1027268..1027552 (+) 285 WP_012677440.1 hypothetical protein -
  FGK99_RS04895 (NCTC4675_00989) rpsT 1027751..1027984 (-) 234 WP_037578328.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49646.28 Da        Isoelectric Point: 9.5548

>NTDB_id=1127179 FGK99_RS04855 WP_138119272.1 1022230..1023540(+) (ciaH) [Streptococcus equi subsp. zooepidemicus strain NCTC4675]
MNKLKKELLSDNYTHFFHFFAIFTGIFVVMTIIILQIMRFSVYSTVDSSLISVGQNASNYANRTMARISSFYFDAENNLI
QALPELEASKSLGSSTTNMDIILFSANGTILNSFDAFSNYQSFRLDKSQLNNIVTTQLMNFYGQKEKYHTLTVKVHIKNY
PAVAYMMAVVNVQQLDTANERYEQIIIMVMIVFWLISILASIYLAKWSRKPIMESYAKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILDNSEHIASSLDEVRNMRILTTNLLNLARRDDGIKPQLVDVDAAFFDTVFENYQLVAEESGKQFISAN
QINRPLKTDKALLKQLMTILFDNAIKYTDHNGVVEVKVRTTDKHLLISVIDNGPGIKDDDKKKIFDRFYRVDKARTRQKG
GFGLGLALAQQIVTSLKGTITVSDNKPTGAIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=1127179 FGK99_RS04855 WP_138119272.1 1022230..1023540(+) (ciaH) [Streptococcus equi subsp. zooepidemicus strain NCTC4675]
ATGAATAAACTAAAAAAAGAATTATTGTCCGATAATTATACACATTTTTTTCATTTCTTTGCTATTTTTACAGGCATTTT
TGTTGTCATGACCATCATTATTTTGCAAATCATGAGGTTTAGTGTCTATTCCACAGTAGACAGCAGTCTCATTTCGGTCG
GTCAAAATGCCAGCAACTATGCCAATAGGACCATGGCGAGAATATCTTCCTTTTATTTTGATGCAGAAAATAACCTTATT
CAGGCTCTTCCTGAGTTGGAAGCGTCAAAATCACTTGGCTCCTCCACCACTAATATGGATATTATTTTATTTAGTGCCAA
TGGGACGATATTGAATTCCTTTGACGCCTTCTCCAATTACCAAAGCTTTCGTTTAGACAAAAGTCAGCTCAATAACATCG
TCACCACACAGCTGATGAATTTTTATGGGCAAAAGGAGAAATACCATACCCTAACCGTTAAGGTCCACATCAAAAATTAT
CCGGCAGTGGCTTATATGATGGCAGTGGTTAATGTTCAGCAACTGGATACTGCCAATGAGCGCTATGAACAGATTATTAT
CATGGTTATGATTGTCTTTTGGTTAATTTCGATTTTAGCCAGCATTTATTTAGCGAAGTGGAGCAGAAAGCCAATTATGG
AGAGCTATGCCAAGCAAAAAATGTTTGTAGAAAATGCCAGTCATGAGCTTAGGACTCCTTTAGCGGTGCTGCAAAATCGT
TTGGAATCGCTGTTTAGAAAGCCTAACGAAACTATTTTAGACAATAGCGAGCATATTGCGTCAAGCCTAGATGAGGTCCG
CAATATGAGAATATTAACCACTAATTTGTTGAATTTAGCTAGACGCGATGATGGGATCAAGCCGCAGCTAGTTGATGTTG
ATGCAGCCTTTTTTGATACTGTTTTTGAAAATTATCAATTAGTTGCAGAAGAATCAGGCAAGCAGTTTATCTCAGCTAAT
CAGATCAATAGACCCTTAAAGACAGATAAGGCCTTACTAAAGCAGCTGATGACCATTTTGTTTGATAACGCGATCAAATA
CACTGATCATAACGGTGTGGTTGAGGTCAAGGTTAGAACGACTGATAAGCATTTATTGATTTCTGTTATTGATAATGGTC
CAGGGATTAAGGATGATGATAAGAAAAAGATTTTTGATCGCTTTTACCGAGTGGATAAGGCAAGGACACGCCAAAAAGGA
GGCTTTGGACTCGGATTGGCCTTAGCGCAGCAGATCGTTACCTCATTAAAAGGAACGATTACCGTCAGTGATAATAAGCC
TACCGGCGCCATCTTTGAAGTAAAATTATAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

57.895

100

0.58
  ciaH Streptococcus pneumoniae Rx1

51.376

100

0.514
  ciaH Streptococcus pneumoniae D39

51.376

100

0.514
  ciaH Streptococcus pneumoniae R6

51.376

100

0.514
  ciaH Streptococcus pneumoniae TIGR4

51.376

100

0.514

Multiple sequence alignment