Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   FGK94_RS08510 Genome accession   NZ_LR590471
Coordinates   1789867..1792023 (-) Length   718 a.a.
NCBI ID   WP_043030064.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC11854     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1784867..1797023
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK94_RS08480 (NCTC11854_01731) - 1784961..1785218 (+) 258 WP_043030068.1 Blp family class II bacteriocin -
  FGK94_RS08485 (NCTC11854_01732) - 1785235..1785429 (+) 195 WP_038674052.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  FGK94_RS08490 (NCTC11854_01733) - 1786063..1786811 (+) 749 Protein_1613 LytR/AlgR family response regulator transcription factor -
  FGK94_RS10510 (NCTC11854_01734) - 1786811..1788145 (+) 1335 WP_043030067.1 sensor histidine kinase -
  FGK94_RS08500 (NCTC11854_01735) - 1788264..1788398 (-) 135 WP_043030066.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  FGK94_RS08505 (NCTC11854_01736) - 1788498..1789856 (-) 1359 WP_043030065.1 bacteriocin secretion accessory protein -
  FGK94_RS08510 (NCTC11854_01737) comA/nlmT 1789867..1792023 (-) 2157 WP_043030064.1 peptide cleavage/export ABC transporter Regulator
  FGK94_RS08515 - 1792313..1792501 (+) 189 WP_229297300.1 leucocin A/sakacin P family class II bacteriocin -
  FGK94_RS08520 (NCTC11854_01738) - 1792501..1792797 (+) 297 WP_043030063.1 bacteriocin immunity protein -
  FGK94_RS08525 (NCTC11854_01739) - 1792950..1793198 (+) 249 WP_043030062.1 garvicin Q family class II bacteriocin -
  FGK94_RS08530 (NCTC11854_01740) - 1793205..1793504 (+) 300 WP_043030073.1 bacteriocin immunity protein -
  FGK94_RS08540 (NCTC11854_01741) - 1794370..1794783 (+) 414 WP_021321055.1 hypothetical protein -
  FGK94_RS08545 (NCTC11854_01742) - 1795034..1795615 (+) 582 WP_043030061.1 GNAT family N-acetyltransferase -
  FGK94_RS08550 (NCTC11854_01744) - 1796352..1796570 (+) 219 WP_021321053.1 hypothetical protein -

Sequence

Protein


Download         Length: 718 a.a.        Molecular weight: 80663.96 Da        Isoelectric Point: 8.0617

>NTDB_id=1126903 FGK94_RS08510 WP_043030064.1 1789867..1792023(-) (comA/nlmT) [Streptococcus equi subsp. zooepidemicus strain NCTC11854]
MTLFYKRTFVPQIDARDCGVAALASIARYYGSDYSLAYLRELAKTNKEGTTALGIVMAAKEMGFETRPIQADMTLFDMAD
VPYPLIVHVNKEGKLQHYYVVYKSKKDYLIIGDPDPMVKVTKMSKERFASEWTGVTICLAPKPNYKPHKDQKNGLLGFFP
LIFKQRALIFYIVLASVLVTVINISGSYYLQGILDEYIPNQLKSTLGIVSIGLIITYILQQLMSFSRDYLLTVLSQRLTI
DVILSYIRHIFELPMSFFATRRTGEVTSRFTDANSIIDALASTILSLFLDLSILAIVGSVLLVQNSRLFLLSLISIPVYT
LIICAFIKPFEQMNHDVMQSNAMLSSAIIEDINGIETIKSLTSEENRYQKIDSDFVDYLDKSFKLSKYTILQATLKQGAQ
LILNIIILWFGAQLVINGKISIGQLITFNTLLAYFTTPLENIINLQTKLQAAKVANNRLNEVYLVEFEFKASQALYDLSL
LQGDIQFEAVSYRYGFGKDTLSDITLTIKQGAKVTLVGVSGSGKTTLAKMLVNFFEPYKGRITINQNDLKTIDKKNLRQY
INYLPQQAYIFNGSILENLTLGAKQGISQEDILKACEIADIRHDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKA
PILVLDEATSGLDILTEKKIIDRLMNMTDKTIIFVAHRLSIAERTDQVVVLNQGQIIETGSHQELMKQGGFYYHLFSE

Nucleotide


Download         Length: 2157 bp        

>NTDB_id=1126903 FGK94_RS08510 WP_043030064.1 1789867..1792023(-) (comA/nlmT) [Streptococcus equi subsp. zooepidemicus strain NCTC11854]
ATGACACTCTTTTATAAAAGAACCTTTGTACCACAAATAGATGCCAGAGATTGTGGCGTAGCTGCTCTAGCCTCAATCGC
AAGGTATTATGGTTCAGATTATTCATTAGCTTATTTGAGAGAATTAGCAAAGACCAATAAGGAAGGGACAACAGCCCTCG
GTATTGTCATGGCTGCTAAGGAAATGGGGTTTGAAACCAGACCTATTCAAGCGGATATGACCCTCTTTGACATGGCAGAC
GTGCCCTATCCATTGATCGTCCATGTCAATAAAGAAGGAAAGCTACAGCACTACTATGTGGTCTACAAATCTAAAAAAGA
CTATCTTATCATTGGTGATCCCGATCCAATGGTCAAGGTCACAAAAATGTCCAAGGAACGCTTTGCTTCTGAATGGACAG
GTGTCACCATATGCCTTGCTCCTAAGCCAAATTATAAACCACATAAAGACCAAAAAAATGGACTATTAGGCTTCTTTCCG
CTTATTTTTAAACAGCGAGCCCTTATATTTTATATCGTGTTAGCTTCTGTCTTGGTAACGGTCATTAATATTTCTGGTTC
ATACTATCTCCAAGGGATTTTAGACGAGTATATTCCAAATCAGCTGAAATCTACCTTAGGGATTGTATCAATTGGTCTCA
TCATTACCTATATACTCCAGCAGCTAATGAGCTTTTCTAGAGATTATCTTTTAACTGTCCTTAGCCAACGTCTTACGATT
GATGTGATCCTGTCCTATATCCGCCATATTTTCGAATTGCCGATGTCCTTTTTTGCAACACGTCGAACAGGTGAGGTAAC
CTCGCGCTTTACAGATGCTAACTCTATCATTGACGCACTCGCTTCAACCATTTTATCCCTCTTTCTAGACCTCTCTATAT
TAGCTATTGTCGGAAGTGTTCTTTTGGTGCAAAATAGCAGGCTTTTTCTGCTATCTCTGATTTCTATCCCAGTATATACC
CTTATCATATGTGCCTTTATAAAGCCGTTTGAACAAATGAATCATGATGTGATGCAAAGCAATGCCATGCTAAGCTCTGC
TATTATCGAAGATATCAACGGGATCGAAACCATAAAATCACTAACCAGTGAAGAAAACCGTTACCAAAAAATTGACAGCG
ACTTTGTGGATTACCTTGATAAGTCTTTTAAGCTTAGTAAATATACCATCTTACAAGCCACACTTAAGCAAGGAGCGCAG
CTAATTCTGAATATCATCATTCTTTGGTTTGGGGCTCAACTGGTCATTAATGGTAAAATTTCAATCGGGCAATTAATTAC
CTTTAACACACTTCTTGCCTATTTTACAACCCCTTTAGAAAATATCATTAATCTTCAAACCAAGCTCCAAGCAGCTAAGG
TTGCCAATAATCGTCTCAATGAGGTCTATCTTGTAGAGTTCGAATTTAAAGCCTCGCAAGCCTTATACGATTTATCGCTC
TTACAGGGTGACATTCAGTTTGAAGCTGTTTCCTACAGGTATGGCTTTGGCAAGGATACATTATCAGATATTACATTAAC
CATTAAGCAGGGAGCAAAAGTAACCCTTGTTGGTGTCAGCGGCTCAGGAAAAACAACCCTAGCCAAGATGCTCGTCAATT
TCTTTGAACCTTATAAGGGACGTATAACCATCAACCAAAACGATCTCAAGACCATTGATAAAAAGAATCTTCGACAATAC
ATCAACTACCTTCCACAACAAGCCTATATCTTTAATGGATCTATCTTAGAAAATCTAACCTTGGGAGCCAAGCAAGGCAT
CAGCCAGGAAGACATTCTTAAAGCCTGTGAGATTGCTGACATTCGTCACGACATCGAGCAAATGCCAATGGGATACCAAA
CCGAGCTCTCTGATGGAGCTGGCTTATCTGGCGGACAAAAACAGAGAATTGCACTGGCTAGAGCATTATTAACCAAAGCT
CCTATACTAGTTCTTGATGAAGCAACCAGCGGACTTGACATACTGACAGAAAAGAAAATCATTGACCGTCTCATGAACAT
GACAGACAAAACGATTATTTTCGTTGCCCACCGGCTTAGTATCGCAGAGCGCACTGATCAGGTTGTTGTTCTTAATCAAG
GGCAAATCATTGAGACAGGCAGCCACCAGGAATTAATGAAACAAGGTGGATTTTATTACCACCTATTTAGTGAATAA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(8-143)

ABC transporter (ABC_tran)

(501-650)

ABC transporter transmembrane region (ABC_membrane)

(169-439)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

70.851

99.861

0.708
  comA Streptococcus mitis SK321

67.461

99.304

0.67
  comA Streptococcus mitis NCTC 12261

67.181

99.304

0.667
  comA Streptococcus pneumoniae Rx1

66.76

99.304

0.663
  comA Streptococcus pneumoniae D39

66.76

99.304

0.663
  comA Streptococcus pneumoniae R6

66.76

99.304

0.663
  comA Streptococcus pneumoniae TIGR4

66.48

99.304

0.66
  comA Streptococcus gordonii str. Challis substr. CH1

65.358

99.304

0.649

Multiple sequence alignment