Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   FGK83_RS03705 Genome accession   NZ_LR590465
Coordinates   737749..738969 (-) Length   406 a.a.
NCBI ID   WP_138171685.1    Uniprot ID   -
Organism   Haemophilus influenzae strain NCTC8468     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 732749..743969
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK83_RS03665 (NCTC8468_00724) - 733655..733861 (-) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  FGK83_RS03670 (NCTC8468_00725) - 733936..734142 (-) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  FGK83_RS03675 (NCTC8468_00726) - 734216..734422 (-) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  FGK83_RS03680 (NCTC8468_00727) - 734496..734702 (-) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  FGK83_RS03685 (NCTC8468_00728) cueR 734779..735165 (+) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  FGK83_RS03690 (NCTC8468_00729) metJ 735179..735496 (-) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  FGK83_RS03695 (NCTC8468_00730) rho 735744..737006 (+) 1263 WP_005648966.1 transcription termination factor Rho -
  FGK83_RS03700 (NCTC8468_00731) pilD 737060..737752 (-) 693 WP_105877453.1 prepilin peptidase Machinery gene
  FGK83_RS03705 (NCTC8468_00732) pilC 737749..738969 (-) 1221 WP_138171685.1 type II secretion system F family protein Machinery gene
  FGK83_RS03710 (NCTC8468_00733) pilB 738966..740360 (-) 1395 WP_138171687.1 GspE/PulE family protein Machinery gene
  FGK83_RS03715 (NCTC8468_00734) pilA 740357..740806 (-) 450 WP_110432056.1 prepilin peptidase-dependent pilin Machinery gene
  FGK83_RS03720 (NCTC8468_00735) ampD 740920..741474 (+) 555 WP_110432055.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  FGK83_RS03725 (NCTC8468_00736) corC 742106..743005 (+) 900 WP_138171689.1 CNNM family magnesium/cobalt transport protein CorC -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46335.59 Da        Isoelectric Point: 9.9102

>NTDB_id=1126750 FGK83_RS03705 WP_138171685.1 737749..738969(-) (pilC) [Haemophilus influenzae strain NCTC8468]
MTKKLFYYQASNALNQKQKGSIIADTKQQAHFQLINRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIVLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLSVVCKRIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLIFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFVLSFFLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSQSLQIMLQAGVPLNQALDSFLPRTQTWQIKKTLVNDIILDKEVRSILQWVSQG
YAFSNSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIAENYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=1126750 FGK83_RS03705 WP_138171685.1 737749..738969(-) (pilC) [Haemophilus influenzae strain NCTC8468]
ATGACTAAAAAACTCTTTTATTATCAAGCTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACAAA
ACAACAAGCACACTTTCAATTAATAAACCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCCACGTTGCTACAGTCCGCTATTCCGTTAAAAAACAGTCTG
CAAATTTTGCAACAAAATTGTACTCAAATTGTACTCAATGAATGGCTTGAACGACTACTTCAATCTATTGAATCTGGTTT
AGCATTCTCACAAGCCATTGAACAACAAGGGAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CGGGAAAACTTTCCGTTGTTTGTAAAAGAATAGCCACACATCGCAGCCAATCTTTAGCATTACAACGTAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGATTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAACAATGCGGAGTTACCAACAATAACCGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGTTTTGAGTTTTTTTCTATTTTATTATTTCTATCTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAGCTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAAGCTGGCGTACCGCTTAATCAGGCACTAGACAGTTTTCTCCCTCGCACACAAACGT
GGCAAATCAAGAAAACGCTTGTAAATGACATCATATTAGATAAAGAAGTGCGGTCAATTTTGCAATGGGTTTCTCAAGGC
TATGCGTTTTCTAATAGTGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGCTACAAATTGGCGAGCAAAGCGG
AAAACTCGCTTTGATGCTAGAGCATATTGCTGAAAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTGATCATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGTTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)

Type II secretion system (T2SS), protein F (T2SSF)

(266-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

98.03

100

0.98
  pilC Haemophilus influenzae 86-028NP

96.798

100

0.968
  pilC Glaesserella parasuis strain SC1401

37.905

98.768

0.374

Multiple sequence alignment