Detailed information NTG1126533

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: E0F34_RS00235
• Genome accession: NZ_LR536843
• Coordinates: 37985..40138 (+)
• Length: 717 a.a.
• NCBI ID: WP_000668280.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 32985..45138

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E0F34_RS00205 (SAMEA104035599_00038)	-	33335..34504 (+)	1170	WP_000366345.1	pyridoxal phosphate-dependent aminotransferase	-
E0F34_RS00210 (SAMEA104035599_00039)	recO	34501..35271 (+)	771	WP_000616162.1	DNA repair protein RecO	-
E0F34_RS00215 (SAMEA104035599_00040)	plsX	35268..36260 (+)	993	WP_050114046.1	phosphate acyltransferase PlsX	-
E0F34_RS00220 (SAMEA104035599_00041)	-	36266..36499 (+)	234	WP_000136447.1	acyl carrier protein	-
E0F34_RS00225 (SAMEA104035599_00042)	-	36536..36835 (+)	300	Protein_40	transposase family protein	-
E0F34_RS00230 (SAMEA104035599_00043)	blpU	37038..37268 (+)	231	WP_001093069.1	bacteriocin-like peptide BlpU	-
E0F34_RS12090 (SAMEA104035599_00044)	-	37271..37396 (+)	126	WP_001842754.1	PncF family bacteriocin immunity protein	-
E0F34_RS00235 (SAMEA104035599_00045)	comA	37985..40138 (+)	2154	WP_000668280.1	peptide cleavage/export ABC transporter ComA	Regulator
E0F34_RS00240 (SAMEA104035599_00046)	comB	40151..41500 (+)	1350	WP_000801606.1	competence pheromone export protein ComB	Regulator
E0F34_RS00245 (SAMEA104035599_00047)	purC	41670..42377 (+)	708	WP_000043305.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80374.42 Da
• Isoelectric Point: 6.4567

>NTDB_id=1126533 E0F34_RS00235 WP_000668280.1 37985..40138(+) (comA) [Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8]
MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKTTMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDL
TFPFVAHVLKEGKLLHYYVVTGQDKDSIHIADPDPGVKLTKLPRERFAEEWTGVTLFMAPSPDYKPHKEQKNGLFSFIPI
LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYILQQILSYAQEYLLLVLGQRLSID
VILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTV
IIFAFMKPFEKMNRDTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQKALKKVAHL
LLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQTAQVANNRLNEVYLVASEFEEKKTVEDLSLM
KGDMTFKQVHYKYGYGRDVLSDINLTVPQGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGSVNLNQIDKKALRQYI
NYLPQQPYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAERTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS

Nucleotide

• Length: 2154 bp

>NTDB_id=1126533 E0F34_RS00235 WP_000668280.1 37985..40138(+) (comA) [Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8]
ATGAAATTTGGGAAACGTCACTATCGTCCGCAAGTGGATCAGATGGACTGCGGTGTAGCTTCATTAGCCATGGTTTTTGG
CTACTATGGTAGTTATTATTTTTTGGCTCACTTGCGAGAATTGGCTAAGACGACCATGGATGGGACGACGGCTTTGGGCT
TGGTCAAGGTGGCAGAGGAGATTGGTTTTGAGACGCGAGCCATTAAGGCGGATATGACGCTTTTTGACTTGCCGGATTTG
ACTTTTCCTTTTGTTGCCCATGTGCTTAAGGAAGGGAAATTGCTCCACTACTATGTGGTGACTGGGCAGGATAAGGATAG
CATTCATATTGCCGACCCAGATCCTGGGGTGAAATTGACCAAACTGCCACGTGAGCGTTTTGCGGAAGAATGGACAGGAG
TGACTCTTTTTATGGCACCTAGTCCAGACTACAAGCCTCATAAGGAACAAAAAAATGGTCTGTTCTCTTTTATCCCTATA
TTAGTGAAGCAGCGTGGCTTGATTGCCAATATCGTTTTGGCAACACTCTTGGTAACCGTGATTAACATTGTGGGTTCTTA
TTATCTGCAGTCTATCATTGATACCTATGTGCCAGATCAGATGCGTTCGACACTAGGGATTATTTCTATTGGGCTAGTCA
TCGTCTACATCCTCCAGCAAATCTTGTCTTACGCTCAGGAGTATCTCTTGCTTGTTTTGGGGCAACGCTTGTCGATTGAC
GTGATTTTGTCCTATATCAAGCATGTTTTTCACCTCCCTATGTCCTTCTTTGCGACACGCAGGACAGGGGAAATCGTGTC
TCGTTTTACAGATGCTAACAGTATCATCGATGCGCTGGCTTCGACCATCCTTTCGATTTTCCTAGATGTGTCAACGGTTG
TCATTATTTCCCTTGTTCTATTTTCACAAAATACCAATCTCTTTTTCATGACTTTATTGGCGCTTCCTATCTACACAGTG
ATTATCTTTGCCTTTATGAAGCCGTTTGAAAAGATGAATCGGGATACCATGGAAGCCAATGCGGTTCTGTCTTCTTCTAT
CATTGAGGACATCAACGGTATTGAGACTATCAAGTCCTTGACCAGTGAAAGTCAGCGTTACCAAAAAATTGACAAGGAAT
TTGTGGATTATCTGAAGAAATCCTTTACCTATAGTCGAGCAGAGAGTCAGCAAAAGGCTCTGAAAAAGGTTGCCCATCTC
TTGCTTAATGTCGGCATTCTCTGGATGGGGGCTGTTCTGGTCATGGATGGCAAGATGAGTTTGGGGCAGTTGATTACCTA
TAATACCTTGCTGGTTTACTTTACCAATCCTTTGGAAAATATCATCAATCTGCAAACCAAGCTTCAGACAGCGCAGGTTG
CCAATAACCGTCTAAATGAAGTGTATCTAGTAGCTTCTGAGTTTGAGGAGAAGAAAACAGTTGAGGATTTGAGCTTGATG
AAGGGAGATATGACCTTCAAGCAGGTTCATTACAAGTATGGCTATGGTCGAGACGTCTTGTCGGATATCAATTTAACCGT
TCCCCAAGGGTCTAAGGTGGCTTTTGTGGGGATTTCAGGGTCAGGTAAGACGACTTTGGCCAAGATGATGGTTAATTTTT
ACGACCCAAGTCAAGGGGAGATTAGTCTGGGTAGTGTCAATCTCAATCAGATTGATAAAAAAGCCCTGCGCCAGTACATA
AACTATCTGCCTCAACAGCCCTATGTCTTTAACGGAACGATTTTGGAGAATCTTCTTTTGGGAGCCAAGGAGGGGACGAC
ACAGGAAGATATCTTACGGGCGGTCGAATTGGCAGAGATTCGAGAGGATATCGAGCGCATGCCACTGAATTATCAGACAG
AATTGACTTCGGATGGGGCAGGGATTTCAGGTGGTCAACGTCAGAGAATCGCTTTGGCGCGTGCTCTCTTGACAGATGCG
CCGGTCTTGATTTTGGATGAGGCGACTAGCAGTTTGGATATTTTGACAGAGAAGCGGATTGTCGATAATCTCATGGCTTT
GGACAAGACCTTGATTTTCATTGCTCACCGCTTGACTATTGCTGAGCGGACAGAGAAGGTGGTTGTCTTGGATCAGGGCA
AGATTGTCGAAGAAGGAAAGCATGCTGATTTGCTTGCACAGGGTGGCTTTTACGCCCATTTGGTCAATAGCTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (500-650)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter transmembrane region (ABC_membrane) (170-438)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus pneumoniae Rx1	99.442	100	0.994
comA	Streptococcus pneumoniae D39	99.442	100	0.994
comA	Streptococcus pneumoniae R6	99.442	100	0.994
comA	Streptococcus pneumoniae TIGR4	99.303	100	0.993
comA	Streptococcus mitis SK321	98.466	100	0.985
comA	Streptococcus mitis NCTC 12261	98.466	100	0.985
comA	Streptococcus gordonii str. Challis substr. CH1	80.335	100	0.803
comA/nlmT	Streptococcus mutans UA159	64.714	100	0.647