Detailed information
Bioinformatically predicted
Overview
| Name | comB | Type | Regulator |
| Locus tag | E0F31_RS00200 | Genome accession | NZ_LR216064 |
| Coordinates | 27592..28941 (+) | Length | 449 a.a. |
| NCBI ID | WP_000801591.1 | Uniprot ID | A0A4V0IRK4 |
| Organism | Streptococcus pneumoniae strain GPSC13 substr. ST473 isolate 569492b0-41bd-11e5-998e-3c4a9275d6c6 | ||
| Function | transport of ComC (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 1720..39046 | 27592..28941 | within | 0 |
Gene organization within MGE regions
Location: 1720..39046
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| E0F31_RS00025 (SAMEA3714520_00005) | - | 1762..3048 (+) | 1287 | WP_000205044.1 | adenylosuccinate synthase | - |
| E0F31_RS00030 (SAMEA3714520_00006) | tadA | 3249..3716 (+) | 468 | WP_000291874.1 | tRNA adenosine(34) deaminase TadA | - |
| E0F31_RS00040 (SAMEA3714520_00007) | - | 3925..5067 (-) | 1143 | WP_000266841.1 | tyrosine-type recombinase/integrase | - |
| E0F31_RS00045 (SAMEA3714520_00008) | - | 5122..6192 (-) | 1071 | WP_000401841.1 | type I restriction endonuclease | - |
| E0F31_RS00050 (SAMEA3714520_00009) | - | 6209..6589 (-) | 381 | WP_000170931.1 | ImmA/IrrE family metallo-endopeptidase | - |
| E0F31_RS00055 (SAMEA3714520_00010) | - | 6602..6865 (-) | 264 | WP_000285962.1 | type II toxin-antitoxin system RelE family toxin | - |
| E0F31_RS00060 (SAMEA3714520_00011) | - | 6865..7098 (-) | 234 | WP_000156419.1 | hypothetical protein | - |
| E0F31_RS00065 (SAMEA3714520_00012) | - | 7098..7466 (-) | 369 | WP_000464160.1 | helix-turn-helix domain-containing protein | - |
| E0F31_RS11985 (SAMEA3714520_00013) | - | 7763..7894 (+) | 132 | WP_000253628.1 | hypothetical protein | - |
| E0F31_RS00075 (SAMEA3714520_00014) | - | 8184..8375 (+) | 192 | WP_001112859.1 | DNA-binding protein | - |
| E0F31_RS00080 (SAMEA3714520_00015) | - | 8398..8601 (+) | 204 | WP_001247549.1 | hypothetical protein | - |
| E0F31_RS00085 (SAMEA3714520_00017) | - | 8756..8923 (-) | 168 | WP_000024181.1 | YjzC family protein | - |
| E0F31_RS00090 (SAMEA3714520_00018) | - | 8928..9308 (+) | 381 | Protein_14 | autolysin | - |
| E0F31_RS00095 (SAMEA3714520_00019) | - | 9582..10025 (+) | 444 | WP_000701990.1 | dUTP diphosphatase | - |
| E0F31_RS00100 (SAMEA3714520_00020) | - | 10027..10542 (+) | 516 | WP_000691237.1 | histidine phosphatase family protein | - |
| E0F31_RS00105 (SAMEA3714520_00021) | radA | 10556..11917 (+) | 1362 | WP_074017595.1 | DNA repair protein RadA | Machinery gene |
| E0F31_RS00110 (SAMEA3714520_00022) | - | 11990..12487 (+) | 498 | WP_001809263.1 | beta-class carbonic anhydrase | - |
| E0F31_RS00115 (SAMEA3714520_00023) | - | 12512..13327 (+) | 816 | WP_000749763.1 | PrsW family intramembrane metalloprotease | - |
| E0F31_RS00120 (SAMEA3714520_00024) | - | 13472..14440 (+) | 969 | WP_000010163.1 | ribose-phosphate diphosphokinase | - |
| E0F31_RS00125 | - | 14574..14855 (-) | 282 | Protein_21 | transposase family protein | - |
| E0F31_RS11580 | - | 14982..15889 (-) | 908 | Protein_22 | Rpn family recombination-promoting nuclease/putative transposase | - |
| E0F31_RS00145 (SAMEA3714520_00028) | polA | 16145..18778 (+) | 2634 | WP_130889213.1 | DNA polymerase I | - |
| E0F31_RS00150 (SAMEA3714520_00029) | - | 18863..19300 (+) | 438 | WP_000076479.1 | CoA-binding protein | - |
| E0F31_RS11585 (SAMEA3714520_00030) | - | 19341..19589 (+) | 249 | WP_000692961.1 | hypothetical protein | - |
| E0F31_RS00160 (SAMEA3714520_00031) | - | 19618..20628 (-) | 1011 | WP_000009170.1 | YeiH family protein | - |
| E0F31_RS00165 (SAMEA3714520_00032) | - | 20777..21946 (+) | 1170 | WP_000366342.1 | pyridoxal phosphate-dependent aminotransferase | - |
| E0F31_RS00170 (SAMEA3714520_00033) | recO | 21943..22713 (+) | 771 | WP_000616122.1 | DNA repair protein RecO | - |
| E0F31_RS00175 (SAMEA3714520_00034) | plsX | 22710..23702 (+) | 993 | WP_000717458.1 | phosphate acyltransferase PlsX | - |
| E0F31_RS00180 (SAMEA3714520_00035) | - | 23708..23941 (+) | 234 | WP_000136449.1 | acyl carrier protein | - |
| E0F31_RS00185 | - | 23978..24278 (+) | 301 | Protein_31 | transposase family protein | - |
| E0F31_RS00190 (SAMEA3714520_00036) | blpU | 24481..24711 (+) | 231 | WP_001093075.1 | bacteriocin-like peptide BlpU | - |
| E0F31_RS11990 (SAMEA3714520_00037) | - | 24714..24839 (+) | 126 | WP_000346297.1 | PncF family bacteriocin immunity protein | - |
| E0F31_RS00195 (SAMEA3714520_00038) | comA | 25426..27579 (+) | 2154 | WP_000668294.1 | peptide cleavage/export ABC transporter ComA | Regulator |
| E0F31_RS00200 (SAMEA3714520_00039) | comB | 27592..28941 (+) | 1350 | WP_000801591.1 | competence pheromone export protein ComB | Regulator |
| E0F31_RS00205 (SAMEA3714520_00040) | purC | 29111..29818 (+) | 708 | WP_000043304.1 | phosphoribosylaminoimidazolesuccinocarboxamide synthase | - |
| E0F31_RS12145 | - | 29829..29963 (+) | 135 | WP_000429436.1 | hypothetical protein | - |
| E0F31_RS00215 (SAMEA3714520_00041) | - | 30020..33745 (+) | 3726 | WP_000361217.1 | phosphoribosylformylglycinamidine synthase | - |
| E0F31_RS00220 (SAMEA3714520_00042) | purF | 33838..35280 (+) | 1443 | WP_050206437.1 | amidophosphoribosyltransferase | - |
| E0F31_RS00225 (SAMEA3714520_00043) | purM | 35317..36339 (+) | 1023 | WP_000182575.1 | phosphoribosylformylglycinamidine cyclo-ligase | - |
| E0F31_RS00230 (SAMEA3714520_00044) | purN | 36336..36881 (+) | 546 | WP_050289164.1 | phosphoribosylglycinamide formyltransferase | - |
| E0F31_RS00235 (SAMEA3714520_00045) | - | 36965..37474 (+) | 510 | WP_000894018.1 | VanZ family protein | - |
| E0F31_RS00240 (SAMEA3714520_00046) | purH | 37499..39046 (+) | 1548 | WP_000167084.1 | bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase | - |
Sequence
Protein
Download Length: 449 a.a. Molecular weight: 49694.60 Da Isoelectric Point: 5.5684
>NTDB_id=1126243 E0F31_RS00200 WP_000801591.1 27592..28941(+) (comB) [Streptococcus pneumoniae strain GPSC13 substr. ST473 isolate 569492b0-41bd-11e5-998e-3c4a9275d6c6]
MKPEFLESAEFYNRRYHNFSSRVIVPMSLLLVFLLGFATFAEKEISLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGDLLVQYQEGAEGVQAESYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYKSQGEENPQIKVQAVAQVEAQIS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLH
LNPETSDSSMVAEGALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE
MKPEFLESAEFYNRRYHNFSSRVIVPMSLLLVFLLGFATFAEKEISLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGDLLVQYQEGAEGVQAESYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYKSQGEENPQIKVQAVAQVEAQIS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLH
LNPETSDSSMVAEGALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE
Nucleotide
Download Length: 1350 bp
>NTDB_id=1126243 E0F31_RS00200 WP_000801591.1 27592..28941(+) (comB) [Streptococcus pneumoniae strain GPSC13 substr. ST473 isolate 569492b0-41bd-11e5-998e-3c4a9275d6c6]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTCGGGTGATTGTACCCAT
GTCCCTTCTGCTCGTGTTTTTACTTGGCTTTGCAACATTTGCGGAGAAGGAGATAAGTTTATCAACTAGAGCTACTGTCG
AGCCTAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGGGGATCTTTTGGTTCAATACCAAGAAGGGGCAGAGGGTGTCCAAGCGGAGTCCTATGCCAGTCAGTTGGA
CATGCTAAAGGATCAAAAAAAGCAATTGGAGTATCTGCAAAAGAGCCTGCAAGAAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAAGCCGAAATCGGCAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATTGAAACAGGTGCTTCCTTGGCCGGTCAGAATCTAGCCTACTCTCTTT
ACCAGTCCTACAAGTCTCAGGGCGAAGAAAATCCCCAAATTAAGGTTCAGGCAGTTGCACAGGTTGAAGCACAGATTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGGTTAAG
CAGTCAATTGGAATCCCTTAAATCCCAACATTTGGCAAAGGTTGGTCAGGAATTGACCCTTCTAGCCCAGAAAATCTTGG
AGGCAGAGTCAGGTAAGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAATTACGGCGAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTAGCATGGTTGCAGAAGGTGCCCTACTAGCCCAACTTTATCCATCTTTGGAAAGAGA
AGGGAAAGCCAAACTCACAGCCTATCTAAGTTCAAAAGATGTAGCAAGAATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCGGGAATCAACTTTTCCTAGATTCTACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAGAAA
GGGAATTTCTTTAAAATCGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTAGGTACGGGGTGGAAGGCCG
CTTGCAGATGATTACGGGCAAGAAAAGTTACCTACGTTATTATTTGGATCAATTTTTGAACAAAGAGTAA
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTCGGGTGATTGTACCCAT
GTCCCTTCTGCTCGTGTTTTTACTTGGCTTTGCAACATTTGCGGAGAAGGAGATAAGTTTATCAACTAGAGCTACTGTCG
AGCCTAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGGGGATCTTTTGGTTCAATACCAAGAAGGGGCAGAGGGTGTCCAAGCGGAGTCCTATGCCAGTCAGTTGGA
CATGCTAAAGGATCAAAAAAAGCAATTGGAGTATCTGCAAAAGAGCCTGCAAGAAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAAGCCGAAATCGGCAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATTGAAACAGGTGCTTCCTTGGCCGGTCAGAATCTAGCCTACTCTCTTT
ACCAGTCCTACAAGTCTCAGGGCGAAGAAAATCCCCAAATTAAGGTTCAGGCAGTTGCACAGGTTGAAGCACAGATTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGGTTAAG
CAGTCAATTGGAATCCCTTAAATCCCAACATTTGGCAAAGGTTGGTCAGGAATTGACCCTTCTAGCCCAGAAAATCTTGG
AGGCAGAGTCAGGTAAGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAATTACGGCGAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTAGCATGGTTGCAGAAGGTGCCCTACTAGCCCAACTTTATCCATCTTTGGAAAGAGA
AGGGAAAGCCAAACTCACAGCCTATCTAAGTTCAAAAGATGTAGCAAGAATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCGGGAATCAACTTTTCCTAGATTCTACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAGAAA
GGGAATTTCTTTAAAATCGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTAGGTACGGGGTGGAAGGCCG
CTTGCAGATGATTACGGGCAAGAAAAGTTACCTACGTTATTATTTGGATCAATTTTTGAACAAAGAGTAA
Domains
No domain identified.
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comB | Streptococcus pneumoniae TIGR4 |
98.441 |
100 |
0.984 |
| comB | Streptococcus pneumoniae D39 |
98.218 |
100 |
0.982 |
| comB | Streptococcus pneumoniae R6 |
98.218 |
100 |
0.982 |
| comB | Streptococcus pneumoniae Rx1 |
98.218 |
100 |
0.982 |
| comB | Streptococcus mitis SK321 |
95.546 |
100 |
0.955 |
| comB | Streptococcus mitis NCTC 12261 |
94.655 |
100 |
0.947 |
| comB | Streptococcus gordonii str. Challis substr. CH1 |
55.778 |
100 |
0.559 |