Detailed information NTG1126184

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: E0F39_RS05015
• Genome accession: NZ_LR216060
• Coordinates: 925618..926571 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain GPSC47 substr. ST315
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 920618..931571

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E0F39_RS04990	rpmG	921361..921510 (+)	150	WP_001864638.1	50S ribosomal protein L33	-
E0F39_RS04995 (SAMEA3713867_00936)	secG	921550..921783 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
E0F39_RS05000 (SAMEA3713867_00937)	rnr	921885..924239 (+)	2355	WP_001864639.1	ribonuclease R	-
E0F39_RS05005 (SAMEA3713867_00938)	smpB	924202..924669 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
E0F39_RS05010 (SAMEA3713867_00939)	tehB	924685..925545 (+)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
E0F39_RS05015 (SAMEA3713867_00940)	coiA	925618..926571 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
E0F39_RS05020 (SAMEA3713867_00941)	pepF	926590..928410 (+)	1821	WP_050199035.1	oligoendopeptidase F	Regulator
E0F39_RS05025 (SAMEA3713867_00942)	-	928412..929125 (+)	714	WP_000230399.1	O-methyltransferase	-
E0F39_RS05030 (SAMEA3713867_00943)	prsA	929192..930133 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
E0F39_RS05035 (SAMEA3713867_00944)	-	930250..930591 (-)	342	Protein_958	transposase	-
E0F39_RS05045	-	931004..931099 (+)	96	Protein_959	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=1126184 E0F39_RS05015 WP_000495909.1 925618..926571(+) (coiA) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=1126184 E0F39_RS05015 WP_000495909.1 925618..926571(+) (coiA) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTAAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGATATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435