Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   E0F39_RS05020 Genome accession   NZ_LR216060
Coordinates   926590..928410 (+) Length   606 a.a.
NCBI ID   WP_050199035.1    Uniprot ID   A0AA44MT55
Organism   Streptococcus pneumoniae strain GPSC47 substr. ST315     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 921590..933410
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0F39_RS05000 (SAMEA3713867_00937) rnr 921885..924239 (+) 2355 WP_001864639.1 ribonuclease R -
  E0F39_RS05005 (SAMEA3713867_00938) smpB 924202..924669 (+) 468 WP_001051750.1 SsrA-binding protein SmpB -
  E0F39_RS05010 (SAMEA3713867_00939) tehB 924685..925545 (+) 861 WP_000413762.1 SAM-dependent methyltransferase TehB -
  E0F39_RS05015 (SAMEA3713867_00940) coiA 925618..926571 (+) 954 WP_000495909.1 competence protein CoiA Machinery gene
  E0F39_RS05020 (SAMEA3713867_00941) pepF 926590..928410 (+) 1821 WP_050199035.1 oligoendopeptidase F Regulator
  E0F39_RS05025 (SAMEA3713867_00942) - 928412..929125 (+) 714 WP_000230399.1 O-methyltransferase -
  E0F39_RS05030 (SAMEA3713867_00943) prsA 929192..930133 (+) 942 WP_000727935.1 peptidylprolyl isomerase PrsA -
  E0F39_RS05035 (SAMEA3713867_00944) - 930250..930591 (-) 342 Protein_958 transposase -
  E0F39_RS05045 - 931004..931099 (+) 96 Protein_959 IS630 family transposase -
  E0F39_RS05050 (SAMEA3713867_00946) - 931352..931972 (-) 621 WP_000780813.1 histidine phosphatase family protein -
  E0F39_RS05055 (SAMEA3713867_00947) - 931972..932454 (-) 483 WP_001085888.1 aminoacyl-tRNA deacylase -
  E0F39_RS05060 (SAMEA3713867_00948) - 932454..933296 (-) 843 WP_000954122.1 DUF368 domain-containing protein -

Sequence

Protein


Download         Length: 606 a.a.        Molecular weight: 70623.60 Da        Isoelectric Point: 4.5576

>NTDB_id=1126185 E0F39_RS05020 WP_050199035.1 926590..928410(+) (pepF) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
MVLQRNERNEINEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYEGHLLDSADNLLEITEFSLEMERQMEKLYVY
AHMKNDQDTREAKYQEYYAKAMTLYSQLDQAFSFYDPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLKGKDHVLSQREE
ELLAGAGEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQALYATYEQFQHTYAKTLQ
TNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRKHLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFT
YQEALKKAEDALAVLGEDYLSRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSMHS
SYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFRGTVFRQTQFAEFEHAIHQADQNGE
VLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWARIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAG
KSDYPLNVMRKAGVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA

Nucleotide


Download         Length: 1821 bp        

>NTDB_id=1126185 E0F39_RS05020 WP_050199035.1 926590..928410(+) (pepF) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
ATGGTATTACAAAGAAATGAAAGAAATGAAATAAATGAAATAAATGAAAAAGATACATGGGATCTATCAACGATCTACCC
AACTGACCAGGCTTGGGAAGAAGCCTTAAAAGATTTAACAGAACAATTGGAGACAGTAGCCCAGTATGAAGGCCATCTCT
TGGATAGTGCGGATAACCTACTAGAAATCACTGAATTTTCTCTTGAAATGGAACGCCAGATGGAGAAGCTTTACGTTTAT
GCTCATATGAAGAATGACCAGGATACACGTGAAGCTAAGTATCAAGAGTACTATGCCAAGGCCATGACACTCTACAGCCA
GTTAGACCAAGCCTTTTCATTCTATGATCCTGAATTTATGGAGATTAGCGAAAAGCAGTATGCTGACTTTTTAGAAGCTC
AACCAAAGCTGCAGGTTTATCAACACTATTTTGACAAGCTCTTGAAAGGCAAGGATCACGTTCTTTCACAACGTGAAGAA
GAATTATTGGCTGGAGCTGGAGAAATCTTTGGTTCAGCAAGTGAAACCTTCGCTATCTTGGACAATGCGGATATTGTGTT
CCCTTATGTCCTAGACGATGATGGTAAAGAAGTTCAGCTATCTCATGGGACGTACACACGTTTGATGGAGTCTAAAAAAC
GTGAGGTTCGCCGTGGTGCCTATCAAGCTCTTTATGCGACTTACGAACAATTCCAACACACCTATGCCAAAACCTTGCAA
ACCAATGTTAAGGTGCAAAATTACCGTGCTAAAGTTCGTAACTACAAGAGTGCTCGTCATGCAGCCCTCGCAGCGAATTT
TGTTCCAGAAAGTGTTTATGACAATTTGGTAGCAGCAGTTCGCAAGCATTTGCCACTCTTACATCGCTATCTTGAGCTTC
GTTCAAAAATCTTGGGGATTTCAGATCTCAAGATGTACGATGTCTACACACCGCTTTCATCTGTTGAATACAGTTTTACC
TACCAAGAAGCCTTGAAAAAAGCAGAAGATGCTTTGGCAGTCTTGGGTGAGGATTACTTGAGCCGTGTTAAACGTGCCTT
CAGCGAGCGTTGGATTGATGTTTACGAAAATCAAGGCAAGCGTTCAGGTGCCTACTCTGGTGGTTCTTACGATACCAATG
CCTTTATGCTTCTCAACTGGCAGGACAATCTGGACAATCTCTTTACTCTTGTTCATGAAACAGGTCACAGTATGCATTCA
AGCTATACTCGTGAAACTCAGCCTTATGTTTACGGAGATTACTCTATCTTTTTGGCTGAGATTGCCTCAACTACCAATGA
AAATATCTTGACGGAGAAATTATTGGAAGAAGTGGAAGACGACGCAACACGCTTTGCTATTCTCAATAACTTCCTAGATG
GTTTCCGTGGAACAGTTTTCCGCCAAACTCAATTTGCTGAGTTTGAACACGCCATTCACCAAGCAGATCAAAATGGGGAG
GTCTTGACAAGCGATTTCCTAAATAAACTCTACGCAGACTTGAACCAAGAGTATTATGGTTTGAGTAAGGAAGACAATCC
TGAAATCCAATACGAGTGGGCTCGCATTCCACACTTCTACTATAACTACTATGTATATCAATATTCAACTGGCTTTGCGG
CCGCCTCAGCCTTGGCTGAAAAAATTGTCCATGGTAGTCAAGAAGACCGTGACCGCTATATCGACTACCTCAAGGCAGGT
AAGTCGGACTATCCACTTAATGTCATGAGAAAAGCTGGTGTTGATATGGAGAAGGAAGACTACCTCAACGATGCCTTTGC
AGTCTTTGAACGCCGTTTAAATGAGTTTGAAGCCCTTGTTGAAAAATTAGGATTGGCATAA

Domains

Predicted by InterproScan.

Oligopeptidase F (Peptidase_M3_N)

(118-187)

Peptidase family M3 (Peptidase_M3)

(208-587)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

67.742

97.195

0.658

Multiple sequence alignment