Detailed information NTG1126145

Bioinformatically predicted

Overview

• Name: comGE/cglE
• Type: Machinery gene
• Locus tag: E0F32_RS09955
• Genome accession: NZ_LR216050
• Coordinates: 1835369..1835671 (-)
• Length: 100 a.a.
• NCBI ID: WP_000413382.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1830369..1840671

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E0F32_RS09925 (SAMEA3431333_01864)	rnpA	1831056..1831427 (-)	372	WP_000739247.1	ribonuclease P protein component	-
E0F32_RS12190	-	1831444..1831575 (-)	132	WP_000768904.1	hypothetical protein	-
E0F32_RS09930 (SAMEA3431333_01865)	-	1831576..1832766 (-)	1191	WP_000167765.1	acetate kinase	-
E0F32_RS09935 (SAMEA3431333_01866)	comYH	1832817..1833770 (-)	954	WP_000345122.1	class I SAM-dependent methyltransferase	Machinery gene
E0F32_RS09940 (SAMEA3431333_01867)	-	1833831..1834418 (-)	588	WP_000679779.1	class I SAM-dependent methyltransferase	-
E0F32_RS09945 (SAMEA3431333_01868)	comGG/cglG	1834521..1834967 (-)	447	WP_001811371.1	competence type IV pilus minor pilin ComGG	Machinery gene
E0F32_RS09950 (SAMEA3431333_01869)	comGF/cglF	1834945..1835406 (-)	462	WP_000250539.1	competence type IV pilus minor pilin ComGF	Machinery gene
E0F32_RS09955 (SAMEA3431333_01870)	comGE/cglE	1835369..1835671 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
E0F32_RS09960 (SAMEA3431333_01871)	comGD/cglD	1835634..1836038 (-)	405	WP_000588030.1	competence type IV pilus minor pilin ComGD	Machinery gene
E0F32_RS09965 (SAMEA3431333_01872)	comGC/cglC	1836031..1836357 (-)	327	WP_000738625.1	competence type IV pilus major pilin ComGC	Machinery gene
E0F32_RS09970 (SAMEA3431333_01873)	comGB/cglB	1836359..1837375 (-)	1017	WP_074017570.1	competence type IV pilus assembly protein ComGB	Machinery gene
E0F32_RS09975 (SAMEA3431333_01874)	comGA/cglA/cilD	1837323..1838264 (-)	942	WP_000249555.1	competence type IV pilus ATPase ComGA	Machinery gene
E0F32_RS09980 (SAMEA3431333_01875)	-	1838339..1838704 (-)	366	WP_000286415.1	DUF1033 family protein	-
E0F32_RS09985 (SAMEA3431333_01876)	-	1838855..1839913 (-)	1059	WP_000649471.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 100 a.a.
• Molecular weight: 11108.08 Da
• Isoelectric Point: 9.7273

>NTDB_id=1126145 E0F32_RS09955 WP_000413382.1 1835369..1835671(-) (comGE/cglE) [Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide

• Length: 303 bp

>NTDB_id=1126145 E0F32_RS09955 WP_000413382.1 1835369..1835671(-) (comGE/cglE) [Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

• Type II secretory pathway pseudopilin (ComGE) (16-97)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE/cglE	Streptococcus pneumoniae Rx1	100	100	1
comGE/cglE	Streptococcus pneumoniae D39	100	100	1
comGE/cglE	Streptococcus pneumoniae R6	100	100	1
comGE/cglE	Streptococcus pneumoniae TIGR4	100	100	1
comGE/cglE	Streptococcus mitis NCTC 12261	98	100	0.98
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	44.444	90	0.4
comYE	Streptococcus mutans UA159	44.444	90	0.4