Detailed information NTG1126110

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: E0F32_RS04620
• Genome accession: NZ_LR216050
• Coordinates: 848537..849490 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495911.1
• Uniprot ID: Q8DQ27
• Organism: Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 843537..854490

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E0F32_RS04595	rpmG	844280..844429 (+)	150	WP_001810029.1	50S ribosomal protein L33	-
E0F32_RS04600 (SAMEA3431333_00860)	secG	844469..844702 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
E0F32_RS04605 (SAMEA3431333_00861)	rnr	844804..847158 (+)	2355	WP_000654886.1	ribonuclease R	-
E0F32_RS04610 (SAMEA3431333_00862)	smpB	847121..847588 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
E0F32_RS04615 (SAMEA3431333_00863)	tehB	847604..848464 (+)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
E0F32_RS04620 (SAMEA3431333_00864)	coiA	848537..849490 (+)	954	WP_000495911.1	competence protein CoiA	Machinery gene
E0F32_RS04625 (SAMEA3431333_00865)	pepF	849509..851311 (+)	1803	WP_024477773.1	oligoendopeptidase F	Regulator
E0F32_RS04630 (SAMEA3431333_00866)	-	851313..852026 (+)	714	WP_000230399.1	O-methyltransferase	-
E0F32_RS04635 (SAMEA3431333_00867)	prsA	852093..853034 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
E0F32_RS04640 (SAMEA3431333_00868)	-	853151..853492 (-)	342	Protein_876	transposase	-
E0F32_RS04650	-	853905..854000 (+)	96	Protein_877	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38143.79 Da
• Isoelectric Point: 9.1135

>NTDB_id=1126110 E0F32_RS04620 WP_000495911.1 848537..849490(+) (coiA) [Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKGKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKKQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=1126110 E0F32_RS04620 WP_000495911.1 848537..849490(+) (coiA) [Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCTTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGGAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGCCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAAACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: Q8DQ27

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae Rx1	100	100	1
coiA	Streptococcus pneumoniae D39	100	100	1
coiA	Streptococcus pneumoniae R6	100	100	1
coiA	Streptococcus pneumoniae TIGR4	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435