Detailed information NTG1124112

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: EL309_RS04210
• Genome accession: NZ_LR134533
• Coordinates: 859555..860415 (-)
• Length: 286 a.a.
• NCBI ID: WP_004285616.1
• Uniprot ID: A0A448VLV4
• Organism: Neisseria weaveri strain NCTC12742
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 854555..865415

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL309_RS04180 (NCTC12742_00821)	-	854775..855431 (-)	657	WP_231987914.1	phosphatase PAP2 family protein	-
EL309_RS04185 (NCTC12742_00823)	yjgA	855930..856445 (-)	516	WP_004282581.1	ribosome biogenesis factor YjgA	-
EL309_RS04190 (NCTC12742_00824)	pmbA	856579..857907 (+)	1329	WP_004282580.1	metalloprotease PmbA	-
EL309_RS04195 (NCTC12742_00825)	yacG	857972..858154 (-)	183	WP_081463174.1	DNA gyrase inhibitor YacG	-
EL309_RS04200 (NCTC12742_00826)	zapD	858160..858933 (-)	774	WP_004282578.1	cell division protein ZapD	-
EL309_RS04205 (NCTC12742_00827)	coaE	858930..859553 (-)	624	WP_004282577.1	dephospho-CoA kinase	-
EL309_RS04210 (NCTC12742_00828)	pilD	859555..860415 (-)	861	WP_004285616.1	A24 family peptidase	Machinery gene
EL309_RS04215 (NCTC12742_00829)	pilG	860418..861659 (-)	1242	WP_004282575.1	type II secretion system F family protein	Machinery gene
EL309_RS04220 (NCTC12742_00830)	pilF	861683..863362 (-)	1680	WP_004282574.1	type IV-A pilus assembly ATPase PilB	Machinery gene
EL309_RS04225 (NCTC12742_00831)	comE	863589..863894 (-)	306	WP_064130790.1	helix-hairpin-helix domain-containing protein	Machinery gene

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31613.70 Da
• Isoelectric Point: 7.6384

>NTDB_id=1124112 EL309_RS04210 WP_004285616.1 859555..860415(-) (pilD) [Neisseria weaveri strain NCTC12742]
MHQLDLPIYWLLGVAAVFGLLVGSFLNVVIYRLPVMMERSWTVFSKEHLELPLSKEEKQRFDLIKPDSRCPTCHTPVRFW
QNIPVISYCILKGKCAECATPISKRYPLVELLTSVLFVIVVWQYGVSWFALGGLVLTAFLIALTFIDADTQYLPDSLTLP
LIWLGLLFNWDNGLISLQSAVLGAVLGYSALWLLCYVYRLLTGKIGMGGGDLKLLAALGAWLGVGALPVIVFLSALVGIV
VGLLMKVAKNEHFAFGPSLAIVGWLVFVANTHVSQAIDWWLNASGF

Nucleotide

• Length: 861 bp

>NTDB_id=1124112 EL309_RS04210 WP_004285616.1 859555..860415(-) (pilD) [Neisseria weaveri strain NCTC12742]
ATGCATCAACTCGACTTGCCAATCTATTGGTTATTGGGGGTGGCAGCAGTTTTCGGTTTGTTAGTCGGCAGTTTTTTAAA
TGTTGTCATTTATCGTTTGCCGGTGATGATGGAACGGAGTTGGACTGTATTTTCTAAGGAGCACTTAGAGCTTCCCTTAT
CTAAAGAAGAAAAACAGCGTTTTGATTTGATTAAACCTGATTCACGTTGCCCTACTTGCCATACACCTGTCAGATTTTGG
CAGAATATTCCGGTAATCAGCTATTGTATTCTGAAAGGAAAATGTGCCGAATGCGCCACGCCGATCAGTAAGCGGTATCC
GTTGGTTGAATTGTTGACATCGGTTTTATTTGTCATTGTCGTTTGGCAGTATGGAGTGAGTTGGTTCGCTCTAGGTGGTT
TGGTGCTTACAGCTTTTTTGATTGCTTTGACGTTTATTGATGCCGATACTCAATATTTGCCCGATTCGCTGACATTACCT
CTCATATGGCTGGGTTTATTATTTAATTGGGACAATGGTTTGATATCCTTGCAGTCTGCTGTTTTGGGTGCGGTGTTGGG
ATATTCCGCTCTGTGGTTATTGTGTTACGTTTACCGATTATTAACAGGTAAGATAGGCATGGGTGGCGGTGATTTGAAAT
TATTGGCCGCTTTAGGTGCATGGTTGGGTGTGGGAGCTTTGCCTGTTATAGTGTTTTTGTCTGCTTTGGTCGGTATAGTG
GTCGGTCTGCTGATGAAGGTAGCAAAAAACGAGCATTTTGCTTTTGGACCGAGTCTTGCGATAGTGGGATGGTTGGTTTT
TGTTGCAAATACCCATGTATCACAAGCTATAGATTGGTGGTTGAACGCTTCGGGATTCTAA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (134-243)

3D structure

• AlphaFold DB: A0A448VLV4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	69.145	94.056	0.65
pilD	Vibrio cholerae strain A1552	46.786	97.902	0.458
pilD	Acinetobacter baumannii D1279779	49.807	90.559	0.451
pilD	Acinetobacter nosocomialis M2	49.421	90.559	0.448
pilD	Vibrio campbellii strain DS40M4	45.714	97.902	0.448