Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   EL147_RS08165 Genome accession   NZ_LR134341
Coordinates   1669240..1671168 (+) Length   642 a.a.
NCBI ID   WP_007892968.1    Uniprot ID   -
Organism   Streptococcus pseudoporcinus strain NCTC13786     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 1664240..1676168
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL147_RS08150 (NCTC13786_01638) fmt 1666217..1667149 (+) 933 WP_007892970.1 methionyl-tRNA formyltransferase -
  EL147_RS08155 (NCTC13786_01639) rsmB 1667142..1668464 (+) 1323 WP_007892980.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  EL147_RS08160 (NCTC13786_01640) - 1668503..1669243 (+) 741 WP_007892963.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  EL147_RS08165 (NCTC13786_01641) pknB 1669240..1671168 (+) 1929 WP_007892968.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  EL147_RS08170 (NCTC13786_01642) liaF 1671282..1671977 (+) 696 WP_007892966.1 cell wall-active antibiotics response protein LiaF -
  EL147_RS08175 (NCTC13786_01643) - 1671974..1672978 (+) 1005 WP_007896177.1 sensor histidine kinase -
  EL147_RS08180 (NCTC13786_01644) - 1672971..1673612 (+) 642 WP_007892962.1 response regulator transcription factor -
  EL147_RS08185 (NCTC13786_01645) - 1673646..1675046 (+) 1401 WP_007892964.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  EL147_RS08190 (NCTC13786_01646) - 1675046..1675399 (+) 354 WP_007892969.1 S1 RNA-binding domain-containing protein -
  EL147_RS08195 (NCTC13786_01647) tnpA 1675587..1676042 (+) 456 WP_007896184.1 IS200/IS605 family transposase -

Sequence

Protein


Download         Length: 642 a.a.        Molecular weight: 70063.48 Da        Isoelectric Point: 8.9691

>NTDB_id=1122024 EL147_RS08165 WP_007892968.1 1669240..1671168(+) (pknB) [Streptococcus pseudoporcinus strain NCTC13786]
MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVLRTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIG
EEDGQQFLVMEYVDGADLKKFIQDNAPLTNNQVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKEGVVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLYEMLTGHIPYDGDSAVTIALQHFQKPLPSIVDENPSVP
QALENVVIKATAKKLSDRYATTFEMSRDLMTALSYNRSREKKLIFDDGENTRPLPKVTPTPNTNPKTSSKEPIASTKAPQ
ASEQLKKPKKEKKRGRFLGTLFKILFALFVVGVAIFTFLILTKPSNVKVPNLSGRDLQTAKADLQALGLKVGNVEQAPSE
DVPEGKVIETNPIAGTTKREGSKVDILVSKGSSGFKVKDYVGDDYQKAMEDLMTTYGLKRKQISIKRVIKDDYNKQDIVL
SQTPNKGYFNPNGKTKFTLTVATTEIIGMPQLIGMTYKDAKLLLEEKGIDLNRVKVYQMNPDGTTTPVEPNSDTLIAYQN
PLLNGQVSLTDTGEISLYINSDSKHVPSSSSSSSSSTETSSESSTSSSSSSSNSSSESSSGSSSTSTSTSTSTSTTSSNT
VQ

Nucleotide


Download         Length: 1929 bp        

>NTDB_id=1122024 EL147_RS08165 WP_007892968.1 1669240..1671168(+) (pknB) [Streptococcus pseudoporcinus strain NCTC13786]
ATGATACAGATTGGCAAATTATTTGCTGGTCGATATCGCATATTAAAATCTATTGGCCGTGGAGGCATGGCAGATGTTTA
TTTAGCTAATGACTTAATTCTAGATAATGAAGACGTGGCAATAAAGGTATTGCGTACTAATTATCAAACGGATCAAGTTG
CTGTCGCACGTTTCCAAAGGGAAGCAAGAGCGATGGCTGAGCTGAATCATCCTAATATCGTAGCTATTAGAGATATAGGC
GAAGAAGACGGGCAGCAATTTTTAGTAATGGAATATGTTGATGGTGCTGATCTTAAGAAGTTCATTCAAGACAATGCACC
TTTGACTAATAATCAAGTCGTTCGGATTATGGAAGAGGTCTTGTCAGCAATGACTTTAGCCCATCAAAAAGGAATTGTCC
ATAGGGATTTAAAGCCGCAGAACATTCTTTTAACTAAAGAAGGTGTTGTCAAAGTCACAGACTTTGGTATTGCTGTTGCT
TTTGCCGAAACCAGCTTAACACAGACTAATTCCATGTTAGGAAGTGTTCATTATTTATCGCCTGAGCAGGCACGTGGCTC
AAAAGCAACCATCCAAAGTGATATCTATGCAATGGGAATCATGCTATATGAAATGTTAACTGGTCACATTCCCTACGATG
GGGATAGTGCGGTAACGATTGCTTTACAACATTTCCAAAAGCCACTCCCTTCCATTGTGGATGAGAATCCCAGTGTGCCA
CAAGCTTTAGAAAATGTTGTTATTAAAGCTACTGCTAAAAAATTGAGTGACCGTTATGCAACGACTTTTGAGATGAGCAG
AGATTTAATGACAGCCTTGAGTTATAACCGTAGTCGTGAAAAGAAGTTGATTTTTGATGACGGTGAGAACACAAGACCTT
TACCCAAAGTGACGCCTACGCCTAATACCAACCCTAAAACAAGCTCTAAGGAACCAATAGCTTCTACTAAAGCACCGCAA
GCTTCAGAACAGCTTAAAAAGCCGAAAAAAGAGAAAAAACGAGGACGTTTCTTAGGAACTCTTTTCAAAATTTTATTTGC
TTTATTTGTGGTTGGTGTAGCTATCTTTACTTTCTTAATTTTAACCAAACCTTCTAATGTTAAAGTTCCTAACCTAAGTG
GTAGAGATTTACAGACTGCTAAAGCAGATTTACAAGCCCTAGGTTTAAAAGTTGGCAATGTTGAGCAGGCACCAAGCGAG
GACGTTCCAGAAGGGAAAGTTATTGAAACGAATCCGATCGCAGGAACAACAAAGCGTGAAGGGTCTAAAGTAGATATTTT
AGTTTCCAAAGGAAGCAGCGGCTTTAAAGTCAAGGATTATGTAGGTGATGATTACCAAAAAGCTATGGAAGATTTAATGA
CTACCTACGGTTTAAAACGTAAACAAATAAGTATCAAACGCGTCATAAAAGATGACTATAATAAGCAAGACATTGTCTTG
AGCCAGACTCCAAATAAGGGCTACTTTAACCCAAATGGGAAAACAAAGTTCACTTTAACGGTTGCAACTACAGAAATAAT
TGGGATGCCGCAACTTATTGGGATGACTTACAAAGATGCTAAACTCTTGCTTGAAGAGAAAGGGATTGATTTAAATCGTG
TTAAAGTTTACCAGATGAATCCGGATGGTACTACGACCCCGGTTGAACCAAACTCTGATACCTTAATAGCTTATCAAAAT
CCTCTCCTTAATGGGCAGGTTTCACTGACGGATACAGGAGAAATTAGTCTCTATATTAATAGTGACAGCAAACATGTTCC
TTCGTCAAGTAGTTCAAGTTCATCAAGTACAGAGACTAGCTCTGAGTCTAGCACTAGTTCAAGTTCTTCTAGTTCAAACT
CCTCTTCGGAGTCAAGTTCTGGATCTAGCTCAACTAGTACTTCAACGAGTACCTCGACATCCACAACGAGTTCAAATACA
GTTCAGTAG

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-233)

PASTA domain (PASTA)

(509-580)

PASTA domain (PASTA)

(367-430)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

62.181

91.433

0.569
  stkP/pknB Streptococcus salivarius strain HSISS4

61.525

91.9

0.565
  stkP Streptococcus pneumoniae TIGR4

61.556

70.093

0.431
  stkP Streptococcus pneumoniae D39

61.111

70.093

0.428
  stkP Streptococcus pneumoniae R6

61.111

70.093

0.428
  stkP Streptococcus pneumoniae Rx1

60.889

70.093

0.427

Multiple sequence alignment