Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   EL147_RS04080 Genome accession   NZ_LR134341
Coordinates   860051..860806 (-) Length   251 a.a.
NCBI ID   WP_007893572.1    Uniprot ID   G5K941
Organism   Streptococcus pseudoporcinus strain NCTC13786     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 855051..865806
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL147_RS04060 (NCTC13786_00812) - 855392..856618 (-) 1227 WP_007893655.1 cysteine desulfurase -
  EL147_RS04065 (NCTC13786_00813) sufD 856634..857899 (-) 1266 WP_007893628.1 Fe-S cluster assembly protein SufD -
  EL147_RS04070 (NCTC13786_00814) sufC 857994..858764 (-) 771 WP_007893650.1 Fe-S cluster assembly ATPase SufC -
  EL147_RS04075 (NCTC13786_00815) - 858890..860044 (-) 1155 WP_007893653.1 glycosyltransferase family 4 protein -
  EL147_RS04080 (NCTC13786_00816) mecA 860051..860806 (-) 756 WP_007893572.1 adaptor protein MecA Regulator
  EL147_RS04085 (NCTC13786_00817) - 860920..861759 (-) 840 WP_007893599.1 undecaprenyl-diphosphate phosphatase -
  EL147_RS04090 (NCTC13786_00818) - 861884..863788 (-) 1905 WP_007893696.1 DUF2207 domain-containing protein -
  EL147_RS04095 (NCTC13786_00819) - 863978..865549 (+) 1572 WP_007893662.1 ABC transporter substrate-binding protein/permease -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 29334.22 Da        Isoelectric Point: 4.1347

>NTDB_id=1122001 EL147_RS04080 WP_007893572.1 860051..860806(-) (mecA) [Streptococcus pseudoporcinus strain NCTC13786]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYTVMDELDLPENFKDSGMLSFRVTPRKDRLDVFVTKSEL
SKEIDFEDLTDLGDVSQMTPEDFFKTIEKNMIEKGDVNAHEKLEKIEEMLEEAVEANQTQTTVSDETTQTVEPMDYVHYV
FDFLTIEEVISFSKIVNFPIEASELYKETNRYHLTILLDIQNQPAYFANIMYARLIEHALPGSRTRAYLQEHATLLIEDQ
AVEQLKKIELV

Nucleotide


Download         Length: 756 bp        

>NTDB_id=1122001 EL147_RS04080 WP_007893572.1 860051..860806(-) (mecA) [Streptococcus pseudoporcinus strain NCTC13786]
ATGGAAATGAAACAAATTAGTGAAACGACACTAAAGATAACAATCAGTATGGATGATTTGGAAGAAAGAGGCATGGAATT
AAAGGATTTTTTAATTCCTCAGGAAAAAACAGAAGAATTTTTCTATACTGTTATGGATGAACTGGATTTACCTGAAAACT
TTAAAGATAGTGGGATGTTAAGTTTTAGGGTTACCCCACGTAAAGATCGTTTAGATGTTTTTGTTACGAAGTCAGAGTTA
TCTAAAGAGATTGATTTTGAGGACTTGACTGATCTAGGAGATGTTTCTCAGATGACGCCCGAAGATTTTTTTAAAACAAT
TGAAAAAAATATGATCGAAAAAGGCGATGTCAACGCTCATGAAAAATTAGAAAAAATTGAAGAAATGTTAGAAGAGGCAG
TTGAGGCAAATCAAACTCAAACGACAGTGAGTGATGAAACTACCCAGACTGTTGAACCGATGGACTACGTCCATTATGTT
TTTGATTTTTTAACTATAGAAGAAGTCATTAGCTTTTCTAAAATAGTCAACTTTCCAATTGAAGCTTCAGAGCTTTACAA
GGAAACGAATCGTTATCACCTGACAATCTTACTTGATATTCAAAATCAGCCAGCCTACTTTGCTAATATTATGTACGCCC
GTCTAATTGAACATGCATTACCTGGTTCAAGGACACGTGCATATTTGCAGGAGCATGCAACCTTACTGATCGAAGATCAA
GCAGTAGAACAGCTGAAAAAGATTGAATTGGTGTGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G5K941

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

61.694

98.805

0.61
  mecA Streptococcus thermophilus LMD-9

57.085

98.406

0.562
  mecA Streptococcus thermophilus LMG 18311

56.68

98.406

0.558
  mecA Streptococcus pneumoniae TIGR4

45.817

100

0.458
  mecA Streptococcus pneumoniae Rx1

45.418

100

0.454
  mecA Streptococcus pneumoniae D39

45.418

100

0.454
  mecA Streptococcus pneumoniae R6

45.418

100

0.454

Multiple sequence alignment