Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   EL140_RS05960 Genome accession   NZ_LR134336
Coordinates   1175943..1176683 (-) Length   246 a.a.
NCBI ID   WP_000782697.1    Uniprot ID   -
Organism   Streptococcus oralis ATCC 35037 strain NCTC 11427     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1170943..1181683
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL140_RS05940 (NCTC11427_01173) msrB 1172442..1173380 (-) 939 WP_000818175.1 peptide-methionine (R)-S-oxide reductase MsrB -
  EL140_RS05950 (NCTC11427_01174) thrB 1173639..1174508 (-) 870 WP_000692412.1 homoserine kinase -
  EL140_RS05955 (NCTC11427_01175) - 1174510..1175796 (-) 1287 WP_000216360.1 homoserine dehydrogenase -
  EL140_RS05960 (NCTC11427_01176) mecA 1175943..1176683 (-) 741 WP_000782697.1 adaptor protein MecA Regulator
  EL140_RS05965 (NCTC11427_01177) - 1176806..1178284 (+) 1479 WP_000789703.1 oligosaccharide flippase family protein -
  EL140_RS05970 (NCTC11427_01178) - 1178330..1180843 (-) 2514 WP_000730139.1 MBL fold metallo-hydrolase -

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28540.36 Da        Isoelectric Point: 4.1437

>NTDB_id=1121853 EL140_RS05960 WP_000782697.1 1175943..1176683(-) (mecA) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
MKMKQISDTTLKITMTLDDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDNFLDSGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLADLPDMEELAQMSPDEFLKTLEKSIADKTKDDIEAIQSLEQVEAKEEEKEQADKETESKKEPYIYYILRFA
SLADLVAFAKTVNYQMETSELYKMNGHYYLTILVDVENHPSPYPAWLLARMREFADDSDISRSVLQEYGQILVNHDAVLN
LQKIRS

Nucleotide


Download         Length: 741 bp        

>NTDB_id=1121853 EL140_RS05960 WP_000782697.1 1175943..1176683(-) (mecA) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
ATGAAGATGAAACAAATCAGTGATACAACACTAAAAATCACGATGACTTTAGATGATTTGATGGACCGAGGAATGGAGAT
TGCAGACTTTCTCGTTCCTCAGGAAAAAACCGAAGAGTTTTTCTATGCTATTTTAGATGAGTTAGAGATGCCAGACAATT
TCTTGGATAGTGGCATGCTGAGTTTCCGCGTGACGCCAAAACCTGATAAGGTGGACGTCTTTGTGACCAAGTCCAAGATT
GACCAGAATTTGGATTTTGAAGATTTGGCGGATCTACCAGACATGGAAGAATTAGCCCAAATGTCGCCTGATGAATTTCT
CAAAACCTTGGAAAAGAGTATTGCAGATAAAACCAAGGACGATATTGAGGCCATCCAATCTCTAGAGCAGGTCGAAGCAA
AGGAAGAAGAGAAAGAGCAGGCAGACAAGGAGACTGAGAGTAAGAAAGAACCTTATATCTACTATATCCTGCGCTTTGCA
AGCCTTGCTGACTTAGTTGCTTTTGCAAAGACGGTTAACTACCAGATGGAAACCTCTGAACTCTATAAGATGAATGGACA
CTACTATTTGACAATCTTAGTCGATGTGGAAAATCATCCAAGTCCATATCCAGCCTGGCTCTTGGCTCGTATGCGTGAGT
TTGCAGATGACAGTGACATCAGTCGTTCCGTTTTGCAAGAGTATGGGCAAATCTTGGTCAATCACGATGCAGTTCTTAAT
CTGCAAAAGATTCGTTCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

90.984

99.187

0.902
  mecA Streptococcus pneumoniae D39

90.984

99.187

0.902
  mecA Streptococcus pneumoniae R6

90.984

99.187

0.902
  mecA Streptococcus pneumoniae TIGR4

90.574

99.187

0.898
  mecA Streptococcus thermophilus LMD-9

47.222

100

0.484
  mecA Streptococcus mutans UA159

48.361

99.187

0.48
  mecA Streptococcus thermophilus LMG 18311

46.825

100

0.48

Multiple sequence alignment