Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   EL133_RS05890 Genome accession   NZ_LR134323
Coordinates   1147437..1148738 (-) Length   433 a.a.
NCBI ID   WP_269208134.1    Uniprot ID   -
Organism   Streptococcus urinalis strain NCTC13766     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1142437..1153738
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL133_RS05865 (NCTC13766_01217) - 1143607..1144656 (-) 1050 WP_006739707.1 BMP family protein -
  EL133_RS05870 (NCTC13766_01218) - 1144757..1145146 (-) 390 WP_006739964.1 cytidine deaminase -
  EL133_RS05875 (NCTC13766_01219) - 1145267..1145854 (-) 588 WP_006738483.1 class I SAM-dependent methyltransferase -
  EL133_RS05880 (NCTC13766_01220) coaA 1146136..1147056 (+) 921 WP_006740427.1 type I pantothenate kinase -
  EL133_RS05885 (NCTC13766_01221) rpsT 1147110..1147361 (+) 252 WP_081479441.1 30S ribosomal protein S20 -
  EL133_RS05890 (NCTC13766_01222) ciaH 1147437..1148738 (-) 1302 WP_269208134.1 cell wall metabolism sensor histidine kinase WalK Regulator
  EL133_RS05895 (NCTC13766_01223) ciaR 1148731..1149405 (-) 675 WP_006738882.1 response regulator transcription factor Regulator
  EL133_RS05900 (NCTC13766_01224) - 1149509..1152046 (-) 2538 WP_006738772.1 M1 family metallopeptidase -
  EL133_RS05905 (NCTC13766_01225) phoU 1152056..1152709 (-) 654 WP_006739252.1 phosphate signaling complex protein PhoU -
  EL133_RS05910 (NCTC13766_01226) pstB 1152747..1153505 (-) 759 WP_006738781.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49361.64 Da        Isoelectric Point: 7.2499

>NTDB_id=1121535 EL133_RS05890 WP_269208134.1 1147437..1148738(-) (ciaH) [Streptococcus urinalis strain NCTC13766]
MTKVSKNLKSGTFSHFFHFFTVFTGIFLVMTILILQIMKFGVYSSADSSLKSVSNNATDYAEKTMERMISLYGSSDKPNT
SSNEKAKPLNDLTANMDIVLFSKDGTVLNPFDTFSAFHSFSLHRRVLNEIVTTSSTNLYGHEETYHTITLKIKSPNYPEI
AYMMVVVNVEQLEEANTRYEKIIIIIMVIFWLISIGASIYLANWSRKPILESYEKQKEFVENASHELRTPLAVLQNRLES
LFRKPETTIIDNSESIASSLEEVRNMRILTTNLLNLARRDDGLKPELAQINPTFFDDIFKNYELIAEDNGKHLTVTNLLS
KSIKSDKTLLKQLMTILFDNAMKYTEEDGHISITIDASDKLFYFTIKDDGPGINEADKKKIFDRFYRVDKARTRQKGGFG
LGLSLAYQIVESLKGTIEVKDNKPKGTVFEVRI

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=1121535 EL133_RS05890 WP_269208134.1 1147437..1148738(-) (ciaH) [Streptococcus urinalis strain NCTC13766]
CTGACTAAAGTTTCAAAAAATCTAAAATCAGGTACATTTAGTCATTTTTTTCATTTTTTTACTGTCTTCACAGGTATCTT
TTTAGTAATGACGATTCTCATTTTACAAATAATGAAGTTTGGTGTTTATTCAAGTGCAGATTCTAGTTTGAAATCAGTAT
CAAATAATGCCACAGATTATGCTGAAAAAACAATGGAAAGAATGATATCACTTTACGGTAGTTCTGATAAGCCAAATACC
TCAAGTAATGAAAAAGCAAAACCTTTAAATGATTTGACTGCTAATATGGATATTGTTCTTTTTTCTAAAGACGGTACCGT
TTTAAATCCATTTGATACCTTCAGTGCCTTTCATTCATTTAGTTTGCATAGACGTGTTTTAAATGAAATTGTCACGACAA
GCTCGACTAATTTATATGGGCATGAGGAAACATACCATACCATAACCCTAAAAATTAAGAGCCCAAACTATCCTGAAATT
GCTTACATGATGGTTGTTGTAAACGTAGAACAACTAGAAGAGGCAAATACAAGATATGAAAAAATTATTATCATTATCAT
GGTGATTTTCTGGCTAATTTCAATTGGTGCTAGTATATATTTAGCAAACTGGAGTCGAAAACCAATATTAGAAAGTTATG
AAAAACAAAAAGAATTTGTTGAAAATGCTAGTCATGAGTTAAGGACACCATTAGCTGTCTTGCAAAACCGCCTAGAGTCT
CTTTTTAGAAAACCCGAGACGACTATTATTGATAATAGTGAAAGCATTGCTTCAAGTTTAGAAGAAGTAAGAAATATGCG
GATTTTAACAACTAATTTATTAAACTTAGCGCGAAGAGACGATGGTTTAAAACCTGAATTAGCACAAATTAATCCTACTT
TCTTTGATGATATTTTTAAAAATTATGAGTTAATAGCTGAAGATAATGGCAAACATTTAACAGTTACAAATTTGTTATCC
AAATCAATCAAATCTGATAAAACACTATTAAAACAATTAATGACTATTTTGTTTGATAACGCAATGAAATACACGGAAGA
AGATGGCCATATTAGTATTACAATAGATGCAAGTGACAAGTTGTTCTATTTTACTATTAAAGATGATGGACCAGGCATTA
ATGAAGCAGATAAGAAAAAGATATTTGATCGTTTTTATAGGGTTGATAAAGCTAGAACACGTCAAAAAGGTGGTTTTGGA
CTAGGCCTTTCTTTAGCATATCAAATTGTAGAATCGCTTAAAGGAACAATTGAAGTCAAAGATAATAAACCCAAAGGAAC
TGTTTTTGAAGTGAGAATTTAA

Domains

Predicted by InterProScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(216-282)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

57.737

100

0.577
  ciaH Streptococcus pneumoniae Rx1

52.074

100

0.522
  ciaH Streptococcus pneumoniae D39

52.074

100

0.522
  ciaH Streptococcus pneumoniae R6

52.074

100

0.522
  ciaH Streptococcus pneumoniae TIGR4

52.074

100

0.522

Multiple sequence alignment