Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   EL133_RS01670 Genome accession   NZ_LR134323
Coordinates   325659..326396 (+) Length   245 a.a.
NCBI ID   WP_006738702.1    Uniprot ID   -
Organism   Streptococcus urinalis strain NCTC13766     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 320659..331396
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL133_RS01645 (NCTC13766_00329) - 321004..321894 (+) 891 WP_006739441.1 SPFH domain-containing protein -
  EL133_RS01650 (NCTC13766_00330) - 321960..322079 (-) 120 WP_006738837.1 putative metal homeostasis protein -
  EL133_RS01655 (NCTC13766_00331) - 322191..322931 (-) 741 WP_006740122.1 amino acid ABC transporter ATP-binding protein -
  EL133_RS01660 (NCTC13766_00332) - 322924..324501 (-) 1578 WP_006739675.1 ABC transporter substrate-binding protein/permease -
  EL133_RS01665 (NCTC13766_00333) - 324717..325556 (+) 840 WP_006739175.1 undecaprenyl-diphosphate phosphatase -
  EL133_RS01670 (NCTC13766_00334) mecA 325659..326396 (+) 738 WP_006738702.1 adaptor protein MecA Regulator
  EL133_RS01675 (NCTC13766_00335) - 326398..327567 (+) 1170 WP_006740478.1 glycosyltransferase family 4 protein -
  EL133_RS01680 (NCTC13766_00336) sufC 327674..328450 (+) 777 WP_006738978.1 Fe-S cluster assembly ATPase SufC -
  EL133_RS01685 (NCTC13766_00337) sufD 328495..329763 (+) 1269 WP_006740653.1 Fe-S cluster assembly protein SufD -
  EL133_RS01690 (NCTC13766_00338) - 329784..331013 (+) 1230 WP_006739900.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28680.44 Da        Isoelectric Point: 4.1758

>NTDB_id=1121512 EL133_RS01670 WP_006738702.1 325659..326396(+) (mecA) [Streptococcus urinalis strain NCTC13766]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYTVMDELDLPENFKDSGMLSFRVTPRKDRLDVFVTKSDL
NKDLNLDDLADMGDVSSMSPEEFFKTLEQSMREKGDTQANEKLEKVEEMMEDAVEATDSEESSTMNPLEYVHYVLDFETI
EDVIRFSKTVDYMTEASELYKENQRYYMTILLDLKDKPEYFANVMYARMLEHAKPGTKTRAYLQEHGILLVDDQAIDHLK
TVKLV

Nucleotide


Download         Length: 738 bp        

>NTDB_id=1121512 EL133_RS01670 WP_006738702.1 325659..326396(+) (mecA) [Streptococcus urinalis strain NCTC13766]
ATGGAAATGAAACAGATAAGTGAAACAACCTTAAAAATTACAATTAGTATGGATGATTTAGAAGAAAGAGGAATGGAATT
AAAAGATTTTTTGATTCCTCAAGAAAAAACTGAAGAATTTTTCTACACTGTAATGGATGAGCTAGATCTTCCTGAAAATT
TCAAAGACAGTGGGATGCTAAGCTTTAGAGTGACTCCTAGAAAAGATAGATTAGATGTTTTTGTGACAAAATCAGATTTA
AATAAAGACCTTAATTTAGATGATTTGGCCGATATGGGTGATGTTTCTTCAATGTCACCAGAGGAATTTTTCAAAACATT
AGAGCAATCTATGCGTGAAAAAGGTGATACACAAGCCAATGAAAAGCTTGAAAAAGTTGAAGAAATGATGGAGGATGCAG
TAGAAGCCACTGATAGTGAAGAATCTTCAACTATGAATCCATTAGAATATGTTCATTATGTTCTTGATTTTGAAACAATT
GAAGATGTTATTCGTTTTTCAAAAACTGTTGACTATATGACGGAAGCTTCAGAACTTTATAAAGAAAATCAACGTTATTA
CATGACCATTTTACTTGATTTAAAAGATAAACCTGAGTATTTCGCAAATGTCATGTATGCAAGAATGTTAGAACATGCTA
AGCCAGGAACAAAAACAAGAGCTTATTTACAAGAACATGGCATACTTTTGGTAGATGATCAAGCAATTGATCACTTAAAG
ACAGTAAAGTTGGTGTGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

68.182

98.776

0.673
  mecA Streptococcus thermophilus LMD-9

57.831

100

0.588
  mecA Streptococcus thermophilus LMG 18311

57.028

100

0.58
  mecA Streptococcus pneumoniae Rx1

48.583

100

0.49
  mecA Streptococcus pneumoniae D39

48.583

100

0.49
  mecA Streptococcus pneumoniae R6

48.583

100

0.49
  mecA Streptococcus pneumoniae TIGR4

48.583

100

0.49

Multiple sequence alignment