Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   EL130_RS01760 Genome accession   NZ_LR134320
Coordinates   348633..349214 (-) Length   193 a.a.
NCBI ID   WP_002264115.1    Uniprot ID   -
Organism   Streptococcus mutans strain NCTC10832     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 333691..367693 348633..349214 within 0


Gene organization within MGE regions


Location: 333691..367693
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL130_RS01690 (NCTC10832_00318) - 333691..335070 (-) 1380 WP_002283797.1 Eco57I restriction-modification methylase domain-containing protein -
  EL130_RS01695 (NCTC10832_00319) - 335146..336021 (-) 876 WP_002277371.1 Abi family protein -
  EL130_RS01710 (NCTC10832_00320) - 336511..337020 (-) 510 WP_002277793.1 HXXEE domain-containing protein -
  EL130_RS01715 (NCTC10832_00321) - 337188..337730 (+) 543 WP_002277792.1 TetR/AcrR family transcriptional regulator -
  EL130_RS01720 (NCTC10832_00322) purH 337913..339463 (-) 1551 WP_002283934.1 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase -
  EL130_RS01725 (NCTC10832_00323) - 339805..340308 (-) 504 WP_002268986.1 hypothetical protein -
  EL130_RS01730 (NCTC10832_00324) purN 340326..340880 (-) 555 WP_002283935.1 phosphoribosylglycinamide formyltransferase -
  EL130_RS01735 (NCTC10832_00325) purM 340880..341902 (-) 1023 WP_002268988.1 phosphoribosylformylglycinamidine cyclo-ligase -
  EL130_RS01740 (NCTC10832_00326) purF 341961..343400 (-) 1440 WP_002263130.1 amidophosphoribosyltransferase -
  EL130_RS01745 (NCTC10832_00327) - 343426..344046 (-) 621 WP_002276188.1 DNA alkylation repair protein -
  EL130_RS01750 (NCTC10832_00328) - 344069..347794 (-) 3726 WP_126475435.1 phosphoribosylformylglycinamidine synthase -
  EL130_RS01755 (NCTC10832_00329) purC 347804..348511 (-) 708 WP_002283937.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  EL130_RS01760 (NCTC10832_00330) comA 348633..349214 (-) 582 WP_002264115.1 ATP-binding cassette domain-containing protein Regulator
  EL130_RS01765 (NCTC10832_00331) - 349442..349690 (-) 249 WP_002263135.1 acyl carrier protein -
  EL130_RS01770 (NCTC10832_00332) plsX 349692..350690 (-) 999 WP_002283938.1 phosphate acyltransferase PlsX -
  EL130_RS01775 (NCTC10832_00333) recO 350898..351653 (-) 756 WP_002269787.1 DNA repair protein RecO -
  EL130_RS01780 (NCTC10832_00334) - 351643..352818 (-) 1176 WP_002277785.1 pyridoxal phosphate-dependent aminotransferase -
  EL130_RS01785 (NCTC10832_00335) - 352907..353875 (-) 969 WP_002277784.1 ribose-phosphate diphosphokinase -
  EL130_RS01790 (NCTC10832_00336) gbpB 354000..355295 (-) 1296 WP_002264119.1 glucan-binding protein GbpB -
  EL130_RS01795 (NCTC10832_00337) mreD 355405..355911 (-) 507 WP_002263141.1 rod shape-determining protein MreD -
  EL130_RS01800 (NCTC10832_00338) mreC 355913..356731 (-) 819 WP_002263142.1 rod shape-determining protein MreC -
  EL130_RS01915 (NCTC10832_00360) - 363820..365235 (-) 1416 WP_019312459.1 amino acid permease -
  EL130_RS01920 (NCTC10832_00361) ftsH 365723..367693 (-) 1971 WP_002266494.1 ATP-dependent zinc metalloprotease FtsH -

Sequence

Protein


Download         Length: 193 a.a.        Molecular weight: 21345.29 Da        Isoelectric Point: 4.7600

>NTDB_id=1121403 EL130_RS01760 WP_002264115.1 348633..349214(-) (comA) [Streptococcus mutans strain NCTC10832]
MGKSGSGKTTLAKILAGYYTVSSGDSFLDGEKINYSQLRQLVTYVPQQSYVFTGTILDNLLLGAEEEVTDDRLMEVCSIA
EILDDIKAMPLGFQTQISEDGGLSGGQKQRLAIARALLTRQPVLIFDEATSGLDRDTEEKVIANLSKLDRTIIFIAHRGS
VSYYADRIVEIDSGEKIKDRINHRPFSFLMTTL

Nucleotide


Download         Length: 582 bp        

>NTDB_id=1121403 EL130_RS01760 WP_002264115.1 348633..349214(-) (comA) [Streptococcus mutans strain NCTC10832]
ATGGGGAAAAGTGGTTCTGGAAAGACAACTTTGGCAAAAATTCTTGCAGGCTATTATACTGTTAGTAGCGGTGACTCTTT
CTTAGATGGAGAAAAGATAAATTATTCCCAGCTGCGCCAATTAGTAACTTATGTGCCACAGCAGTCTTATGTTTTTACAG
GAACAATCTTAGATAATCTGCTTCTTGGTGCTGAAGAGGAAGTAACGGATGATCGCTTAATGGAAGTTTGTTCAATTGCT
GAAATTTTAGACGATATCAAGGCAATGCCTTTAGGTTTTCAAACACAGATTTCAGAAGACGGCGGTTTATCTGGTGGTCA
AAAACAGCGTTTAGCTATTGCACGTGCTCTCTTAACCAGACAGCCTGTGTTGATTTTTGATGAGGCAACTAGTGGTTTAG
ATCGTGATACCGAAGAAAAAGTTATTGCCAATTTATCTAAATTGGATCGCACGATTATTTTTATTGCTCACCGAGGCAGT
GTTTCTTATTATGCTGATCGAATTGTTGAGATTGACTCTGGAGAGAAAATTAAGGATAGAATAAATCATCGTCCTTTCTC
ATTTTTGATGACGACTCTTTGA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(1-131)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

51.872

96.891

0.503
  comA Streptococcus gordonii str. Challis substr. CH1

52.198

94.301

0.492
  comA/nlmT Streptococcus mutans UA159

49.468

97.409

0.482
  comA Streptococcus pneumoniae D39

50.273

94.819

0.477
  comA Streptococcus pneumoniae Rx1

50.273

94.819

0.477
  comA Streptococcus pneumoniae R6

50.273

94.819

0.477
  comA Streptococcus mitis SK321

49.18

94.819

0.466
  comA Streptococcus pneumoniae TIGR4

49.18

94.819

0.466

Multiple sequence alignment