Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   EL136_RS10760 Genome accession   NZ_LR134317
Coordinates   2251783..2252547 (+) Length   254 a.a.
NCBI ID   WP_154804364.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC6180     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 2246783..2257547
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL136_RS10740 (NCTC6180_02200) - 2247768..2247884 (-) 117 WP_012677375.1 putative metal homeostasis protein -
  EL136_RS10745 (NCTC6180_02201) - 2248207..2248947 (-) 741 WP_012680102.1 amino acid ABC transporter ATP-binding protein -
  EL136_RS10750 (NCTC6180_02202) - 2248940..2250508 (-) 1569 WP_154804362.1 ABC transporter substrate-binding protein/permease -
  EL136_RS10755 (NCTC6180_02203) - 2250824..2251663 (+) 840 WP_154804363.1 undecaprenyl-diphosphate phosphatase -
  EL136_RS10760 (NCTC6180_02204) mecA 2251783..2252547 (+) 765 WP_154804364.1 adaptor protein MecA Regulator
  EL136_RS10765 (NCTC6180_02205) - 2252554..2253711 (+) 1158 WP_012680099.1 glycosyltransferase family 4 protein -
  EL136_RS10770 (NCTC6180_02206) sufC 2253832..2254602 (+) 771 WP_042357214.1 Fe-S cluster assembly ATPase SufC -
  EL136_RS10775 (NCTC6180_02207) sufD 2254693..2255955 (+) 1263 WP_154804365.1 Fe-S cluster assembly protein SufD -
  EL136_RS10780 (NCTC6180_02208) - 2255982..2257208 (+) 1227 WP_154804366.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 254 a.a.        Molecular weight: 29318.15 Da        Isoelectric Point: 4.2602

>NTDB_id=1121304 EL136_RS10760 WP_154804364.1 2251783..2252547(+) (mecA) [Streptococcus equi subsp. zooepidemicus strain NCTC6180]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYAVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSDL
NKDLNFEDLADLGDISQMTPEDFFRSLEQSMREKGDVNAHEKVEKIEEIMEDVVDATLAEQADNKEAAELEEPTEPLDYV
HYVLDFASVRDAVCFAKAIDFPIEASELYKGPRHYHMTILLDVQNKPAYFANVMYARLIEHARPGTKTRAYLQEHGCQLI
FDGAVEELQKIRLG

Nucleotide


Download         Length: 765 bp        

>NTDB_id=1121304 EL136_RS10760 WP_154804364.1 2251783..2252547(+) (mecA) [Streptococcus equi subsp. zooepidemicus strain NCTC6180]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGACGATTTAGAAGAAAGGGGTATGGAACT
CAAGGACTTCTTGATCCCTCAAGAAAAGACAGAGGAGTTCTTTTATGCTGTCATGGACGAGTTGGACCTTCCGGACAATT
TTAAGGACAGTGGTATGCTTAGCTTTCGAGTGACCCCAAGAAAGGATCGCTTAGATGTTTTTGTGACCAAGTCAGACCTC
AATAAGGACCTTAATTTTGAGGATTTGGCAGACCTAGGTGATATTTCTCAAATGACTCCAGAGGATTTTTTCAGGAGCTT
GGAGCAGTCTATGCGTGAAAAGGGTGATGTTAATGCCCATGAAAAGGTCGAAAAAATTGAGGAGATCATGGAGGACGTGG
TTGATGCTACCTTGGCTGAGCAAGCAGATAATAAGGAAGCTGCTGAGCTTGAAGAGCCGACAGAGCCACTTGATTACGTT
CACTATGTTCTTGATTTTGCTTCTGTGCGAGACGCTGTTTGCTTTGCTAAGGCGATTGATTTTCCGATCGAGGCCTCTGA
ATTGTATAAGGGTCCTCGTCATTATCACATGACAATCTTACTTGATGTGCAAAACAAGCCTGCCTATTTTGCCAATGTGA
TGTATGCAAGATTGATTGAGCATGCTAGACCTGGTACAAAAACAAGAGCTTATTTGCAGGAGCATGGTTGTCAGCTCATT
TTTGATGGTGCTGTTGAGGAGCTGCAAAAAATCAGGTTGGGGTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

63.347

98.819

0.626
  mecA Streptococcus thermophilus LMD-9

56.078

100

0.563
  mecA Streptococcus thermophilus LMG 18311

55.294

100

0.555
  mecA Streptococcus pneumoniae TIGR4

48.031

100

0.48
  mecA Streptococcus pneumoniae Rx1

47.638

100

0.476
  mecA Streptococcus pneumoniae D39

47.638

100

0.476
  mecA Streptococcus pneumoniae R6

47.638

100

0.476

Multiple sequence alignment