Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   EL136_RS06590 Genome accession   NZ_LR134317
Coordinates   1380206..1381573 (-) Length   455 a.a.
NCBI ID   WP_043029447.1    Uniprot ID   A0A2X3T9T4
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC6180     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1375206..1386573
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL136_RS06570 (NCTC6180_01349) nrdE 1375358..1377532 (-) 2175 WP_154804072.1 class 1b ribonucleoside-diphosphate reductase subunit alpha -
  EL136_RS06575 (NCTC6180_01350) nrdI 1377578..1377988 (-) 411 WP_043052823.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  EL136_RS06580 (NCTC6180_01351) nrdF 1377990..1379003 (-) 1014 WP_012678369.1 class 1b ribonucleoside-diphosphate reductase subunit beta -
  EL136_RS06585 (NCTC6180_01352) - 1379461..1379697 (-) 237 WP_024273149.1 hypothetical protein -
  EL136_RS06590 (NCTC6180_01353) comB 1380206..1381573 (-) 1368 WP_043029447.1 bacteriocin secretion accessory protein Regulator
  EL136_RS06595 (NCTC6180_01354) comA 1381588..1383741 (-) 2154 WP_012515169.1 peptide cleavage/export ABC transporter ComA Regulator
  EL136_RS06600 (NCTC6180_01355) - 1383968..1384135 (-) 168 WP_012515168.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  EL136_RS06605 (NCTC6180_01356) - 1384158..1384304 (-) 147 WP_021320464.1 hypothetical protein -
  EL136_RS06610 (NCTC6180_01357) - 1384318..1384476 (-) 159 WP_021320463.1 hypothetical protein -
  EL136_RS06615 (NCTC6180_01358) - 1384589..1384729 (-) 141 WP_012515166.1 hypothetical protein -
  EL136_RS06620 (NCTC6180_01359) - 1385069..1385962 (-) 894 WP_024273139.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 455 a.a.        Molecular weight: 50826.94 Da        Isoelectric Point: 5.1918

>NTDB_id=1121279 EL136_RS06590 WP_043029447.1 1380206..1381573(-) (comB) [Streptococcus equi subsp. zooepidemicus strain NCTC6180]
MNNNILESAEFYNRRYHNFSSRIILPTLLLFLFGVFFLAFAKKEISIISTATVEPNIILSNIQSTSNNTILTNNLKDNKY
VKFGDLLIKYDSRKEGIQQETYQTQLNNLQIQKEQLELLKASIEAGNSQFPEKDNYGYYQTFIDYLNQINTLSANVNQQN
ENVSSQNTAASNQQVEIENAIKGLTSQISDYQSVRSAIQNGTVVDLDNRAYSIYRSYLTQTSSLVDNTDKTAVINQFVAQ
IDSQINQLESSVAGYRIQHAGSGVQQSYSSTLESQLASLKAQSITKVEQELSALSNQITELEGTNKLQKNTSSKTSIVAN
EDGVLHLNQEFIGANIVPEGTIFAQVYPEMKKGTVVKITGYLPSTEISSISIGDTARFSTKDDNGETLDLIVKLSSIDNA
ATKTKNGNYFKVESKLQLKEKEAQLLKYGLEGKFILITGTKSYLNYYIDKFIGEK

Nucleotide


Download         Length: 1368 bp        

>NTDB_id=1121279 EL136_RS06590 WP_043029447.1 1380206..1381573(-) (comB) [Streptococcus equi subsp. zooepidemicus strain NCTC6180]
ATGAATAACAATATATTAGAAAGTGCGGAATTTTATAACCGTCGTTACCACAACTTTTCTAGTCGTATCATTCTACCTAC
TTTGCTGCTTTTCTTGTTTGGTGTTTTCTTCCTAGCATTTGCAAAGAAAGAAATTTCTATTATTTCAACTGCAACAGTTG
AACCAAATATAATTCTTTCCAATATTCAATCTACAAGTAATAATACAATATTAACCAATAATCTAAAAGATAATAAATAT
GTCAAATTTGGAGACTTATTGATAAAATATGATTCAAGAAAAGAAGGTATTCAACAAGAGACCTATCAAACTCAATTAAA
TAATTTACAAATCCAAAAAGAACAGTTAGAGCTATTAAAAGCAAGTATTGAAGCTGGAAACAGTCAATTTCCAGAAAAAG
ATAATTATGGATATTATCAAACATTTATTGACTACTTAAATCAGATAAACACCTTATCAGCCAATGTAAATCAGCAAAAT
GAAAATGTCTCTTCACAAAATACTGCAGCTAGCAATCAGCAAGTAGAAATTGAGAATGCCATCAAAGGTCTCACAAGTCA
AATTTCAGATTATCAATCTGTTCGCTCGGCGATTCAAAATGGAACAGTGGTAGATCTTGATAATCGGGCTTATTCTATCT
ATAGGAGTTATCTAACTCAAACATCGAGTTTGGTAGATAATACTGATAAAACCGCTGTTATTAATCAATTTGTTGCTCAA
ATTGATAGTCAGATCAATCAACTAGAGAGTAGTGTAGCTGGTTATCGGATTCAGCATGCTGGTTCAGGAGTGCAACAATC
TTACTCTTCAACTCTAGAGAGTCAACTGGCTTCCTTAAAAGCGCAAAGCATAACCAAAGTTGAGCAAGAGTTGTCTGCTT
TGTCGAATCAAATTACAGAATTAGAGGGAACAAATAAACTTCAGAAGAACACATCATCTAAGACCTCTATAGTTGCCAAT
GAAGATGGTGTGTTGCATCTTAATCAGGAATTTATTGGTGCAAATATTGTTCCTGAAGGAACAATATTTGCTCAAGTTTA
TCCAGAAATGAAAAAAGGAACTGTTGTAAAAATCACAGGTTATTTACCTTCGACGGAAATATCAAGTATTTCTATTGGAG
ATACAGCACGATTTTCCACGAAAGATGATAATGGCGAAACTCTTGATTTAATAGTTAAATTATCTAGTATTGACAATGCT
GCAACTAAAACAAAAAATGGGAATTATTTTAAAGTTGAATCTAAGTTACAGCTTAAAGAAAAAGAAGCTCAATTATTGAA
ATATGGGCTTGAGGGTAAATTTATTTTAATTACGGGAACAAAAAGTTACTTGAATTACTATATTGATAAATTTATCGGTG
AGAAGTAA

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(317-429)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2X3T9T4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae Rx1

50

99.341

0.497
  comB Streptococcus pneumoniae D39

50

99.341

0.497
  comB Streptococcus pneumoniae R6

50

99.341

0.497
  comB Streptococcus pneumoniae TIGR4

49.115

99.341

0.488
  comB Streptococcus mitis NCTC 12261

48.894

99.341

0.486
  comB Streptococcus mitis SK321

48.673

99.341

0.484
  comB Streptococcus gordonii str. Challis substr. CH1

47.894

99.121

0.475

Multiple sequence alignment