Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   EL136_RS04070 Genome accession   NZ_LR134317
Coordinates   850410..851084 (-) Length   224 a.a.
NCBI ID   WP_021320708.1    Uniprot ID   A0AAW3GMV5
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC6180     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 845410..856084
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL136_RS04040 (NCTC6180_00830) - 845779..846063 (-) 285 WP_012677440.1 hypothetical protein -
  EL136_RS04045 (NCTC6180_00831) - 846079..846471 (-) 393 WP_154803866.1 hypothetical protein -
  EL136_RS04050 (NCTC6180_00832) - 846468..847661 (-) 1194 WP_154803867.1 hypothetical protein -
  EL136_RS04055 (NCTC6180_00833) - 847672..848055 (-) 384 WP_154803576.1 DUF1433 domain-containing protein -
  EL136_RS04060 (NCTC6180_00834) - 848282..848698 (-) 417 WP_154803868.1 hypothetical protein -
  EL136_RS04065 (NCTC6180_00835) ciaH 849107..850417 (-) 1311 WP_154803869.1 sensor histidine kinase Regulator
  EL136_RS04070 (NCTC6180_00836) ciaR 850410..851084 (-) 675 WP_021320708.1 response regulator transcription factor Regulator
  EL136_RS04075 (NCTC6180_00837) - 851511..854048 (-) 2538 WP_154803870.1 M1 family metallopeptidase -
  EL136_RS04080 (NCTC6180_00838) phoU 854282..854935 (-) 654 WP_012678018.1 phosphate signaling complex protein PhoU -
  EL136_RS04085 (NCTC6180_00839) pstB 855006..855764 (-) 759 WP_012678019.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25569.58 Da        Isoelectric Point: 4.5644

>NTDB_id=1121270 EL136_RS04070 WP_021320708.1 850410..851084(-) (ciaR) [Streptococcus equi subsp. zooepidemicus strain NCTC6180]
MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGIYDLILLDLMLPEKDGFQVLKALREKDIKIPVLIMTA
KESIDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRVGKFNDKSLKFGNLTVDTTRKEVQVNGQVIELLGKELDLLIY
ILQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVNHLQTLRSVGYILKANE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1121270 EL136_RS04070 WP_021320708.1 850410..851084(-) (ciaR) [Streptococcus equi subsp. zooepidemicus strain NCTC6180]
ATGATAAAACTATTATTAGTAGAAGACGATTTAAGCTTGTCAAATTCCATCTTTGATTTTTTAGATGACTTTGCTGATGT
GACCCAGGTTTTTGATGGCGACGAAGGACTCTATGAGGCAGAAAGCGGCATTTATGATTTGATTCTGTTAGATTTGATGC
TGCCTGAAAAGGATGGCTTTCAAGTGCTAAAGGCCTTACGTGAAAAAGACATCAAAATTCCCGTCTTGATCATGACTGCC
AAAGAAAGCATTGATGACAAGGGACATGGCTTTGAGCTTGGTGCTGATGACTATTTAACCAAGCCCTTTTACCTAGAGGA
ATTAAAAATGCGGATTCAGGCCTTGCTTAAGCGCGTAGGAAAGTTTAATGATAAGAGCCTTAAATTTGGCAACCTGACTG
TAGATACTACCCGTAAAGAGGTACAGGTCAATGGGCAGGTCATAGAGCTATTAGGCAAGGAGCTTGATTTACTAATCTAT
ATCCTTCAAAATCAAAATGTTATTTTGCCAAAGTCACAAATTTTTGATCGTATCTGGGGCTTTGATAGTGATACCACTAT
CTCTGTTGTAGAGGTCTATGTCTCTAAAATCCGTAAGAAGCTTAAGGGGACAGACTTTGTTAATCATCTTCAAACCTTGA
GAAGTGTAGGATATATCTTAAAAGCTAATGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae Rx1

80.543

98.661

0.795
  ciaR Streptococcus pneumoniae D39

80.543

98.661

0.795
  ciaR Streptococcus pneumoniae R6

80.543

98.661

0.795
  ciaR Streptococcus pneumoniae TIGR4

80.543

98.661

0.795
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.865

100

0.397

Multiple sequence alignment