Detailed information NTG1121267

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: EL136_RS03825
• Genome accession: NZ_LR134317
• Coordinates: 798211..799056 (-)
• Length: 281 a.a.
• NCBI ID: WP_012677974.1
• Uniprot ID: A0A6M1KS91
• Organism: Streptococcus equi subsp. zooepidemicus strain NCTC6180
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 793211..804056

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL136_RS03810 (NCTC6180_00782)	-	794481..795194 (-)	714	WP_154803848.1	DUF3307 domain-containing protein	-
EL136_RS03815 (NCTC6180_00783)	-	795215..795862 (-)	648	WP_154803849.1	SatD family protein	-
EL136_RS03820 (NCTC6180_00784)	topA	795978..798110 (-)	2133	WP_154803850.1	type I DNA topoisomerase	-
EL136_RS03825 (NCTC6180_00785)	dprA	798211..799056 (-)	846	WP_012677974.1	DNA-processing protein DprA	Machinery gene
EL136_RS03830 (NCTC6180_00786)	-	799301..800074 (-)	774	WP_154803851.1	ribonuclease HII	-
EL136_RS03835 (NCTC6180_00787)	ylqF	800064..800918 (-)	855	WP_012677976.1	ribosome biogenesis GTPase YlqF	-
EL136_RS03840 (NCTC6180_00788)	-	801511..802143 (-)	633	WP_043025814.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 281 a.a.
• Molecular weight: 31330.23 Da
• Isoelectric Point: 8.8540

>NTDB_id=1121267 EL136_RS03825 WP_012677974.1 798211..799056(-) (dprA) [Streptococcus equi subsp. zooepidemicus strain NCTC6180]
MNNFELYKLKKAGLTNLNILNLIDYQQRNNKSLSLRDIAVVSCCKNPVLFIETYKQLNVALLKKEFNQFPSLSILDKQYP
LALREIYNPPVLLFYQGDLSLLEKPKLAVVGSRESSEIGTRSVYKIIKELKNHFVIVSGLARGIDTSAHLACLKAGGQTI
AVIGTGLDRYYPKENHQLQEFLSQRHLVLSEYGAGEAALSYHFPERNRIIAGLSRGVLVVEAKQRSGSLITCQLAMEEGR
DIFVVPDNILNGTSAGCLKLIKDGASCVTHGRDILSEYHYS

Nucleotide

• Length: 846 bp

>NTDB_id=1121267 EL136_RS03825 WP_012677974.1 798211..799056(-) (dprA) [Streptococcus equi subsp. zooepidemicus strain NCTC6180]
ATGAACAATTTTGAACTTTATAAATTAAAAAAGGCTGGGCTGACTAATTTAAATATTCTTAACCTGATTGACTACCAGCA
GCGTAATAACAAGTCTCTATCCCTTAGAGATATAGCAGTGGTTTCTTGCTGCAAAAATCCAGTTTTATTTATTGAGACCT
ACAAGCAATTAAATGTCGCCTTGTTAAAAAAGGAATTCAATCAGTTTCCGAGCTTATCTATCCTAGATAAGCAATACCCA
TTGGCTCTGAGGGAAATCTACAATCCTCCTGTTTTACTCTTTTATCAAGGTGATTTAAGCCTGTTAGAAAAACCTAAGCT
GGCAGTCGTTGGCTCTAGAGAATCCAGTGAAATTGGGACGCGGTCTGTTTATAAAATCATTAAAGAGCTTAAGAATCACT
TTGTCATTGTAAGTGGACTTGCTAGAGGTATTGATACCAGTGCTCATCTCGCTTGCTTGAAAGCAGGTGGGCAAACTATA
GCTGTTATCGGGACTGGCCTAGATCGCTACTATCCAAAGGAAAATCACCAGCTACAGGAGTTTTTATCTCAGCGTCATCT
CGTGCTCAGTGAATATGGGGCTGGAGAGGCCGCCTTGTCTTATCATTTCCCTGAAAGAAACCGTATTATCGCAGGTCTTA
GTCGAGGTGTCCTTGTTGTTGAGGCTAAGCAGCGCTCTGGCTCTTTGATTACCTGTCAGCTAGCTATGGAAGAGGGACGT
GATATTTTTGTCGTACCTGACAATATTCTTAATGGGACATCAGCGGGCTGTTTGAAGCTGATCAAAGATGGTGCCAGCTG
TGTCACTCATGGCAGAGACATTCTTTCAGAATACCACTATTCTTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-61)

• DNA recombination-mediator protein A (DNA_processg_A) (71-269)

3D structure

• AlphaFold DB: A0A6M1KS91

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	68.571	99.644	0.683
dprA/cilB/dalA	Streptococcus mitis SK321	59.643	99.644	0.594
dprA/cilB/dalA	Streptococcus pneumoniae D39	59.286	99.644	0.591
dprA/cilB/dalA	Streptococcus pneumoniae R6	59.286	99.644	0.591
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	59.286	99.644	0.591
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	59.286	99.644	0.591
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	58.929	99.644	0.587
dprA	Lactococcus lactis subsp. cremoris KW2	56.584	100	0.566
dprA	Bacillus subtilis subsp. subtilis str. 168	42.4	88.968	0.377