Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   EL139_RS01415 Genome accession   NZ_LR134316
Coordinates   251132..251893 (-) Length   253 a.a.
NCBI ID   WP_111715159.1    Uniprot ID   A0A9X8SXU1
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC6181     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 246132..256893
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL139_RS01395 (NCTC6181_00287) - 246448..247674 (-) 1227 WP_003062308.1 cysteine desulfurase -
  EL139_RS01400 (NCTC6181_00288) sufD 247705..248967 (-) 1263 WP_111715168.1 Fe-S cluster assembly protein SufD -
  EL139_RS01405 (NCTC6181_00289) sufC 249073..249843 (-) 771 WP_111715165.1 Fe-S cluster assembly ATPase SufC -
  EL139_RS01410 (NCTC6181_00290) - 249956..251125 (-) 1170 WP_111715162.1 MraY family glycosyltransferase -
  EL139_RS01415 (NCTC6181_00291) mecA 251132..251893 (-) 762 WP_111715159.1 adaptor protein MecA Regulator
  EL139_RS01420 (NCTC6181_00292) - 252037..252876 (-) 840 WP_111715157.1 undecaprenyl-diphosphate phosphatase -
  EL139_RS01425 (NCTC6181_00293) - 252944..254869 (-) 1926 WP_111715154.1 DUF2207 domain-containing protein -
  EL139_RS01430 (NCTC6181_00294) - 255068..256636 (+) 1569 WP_111715151.1 ABC transporter substrate-binding protein/permease -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29141.77 Da        Isoelectric Point: 4.0570

>NTDB_id=1121202 EL139_RS01415 WP_111715159.1 251132..251893(-) (mecA) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6181]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEL
NKDLNLEDLADLGDISQMTPEDFFKSLEQSMREKGDVNAHEKLEKIEEMMEDVVEATLASQTEETAEEVDQEPEPLDYVH
YVLDFATLSEAVAFSQTIDFPVEASELYKGDSRYHMTILLDVQQQPSYFVNVMYARLIEHASPGTKTRAYLQEHGVQLIL
DGAVEQLRKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=1121202 EL139_RS01415 WP_111715159.1 251132..251893(-) (mecA) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6181]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGATGATTTAGAAGAAAGAGGGATGGAATT
AAAAGATTTCCTCATTCCTCAAGAAAAAACGGAAGAGTTCTTTTACTCTGTTATGGATGAGTTGGATCTACCAGACAATT
TCAAAGATAGTGGCATGCTTAGCTTTCGTGTGACCCCTAGAAAAGACCGTTTGGATGTCTTTGTAACCAAGTCTGAACTC
AATAAGGACCTTAATCTGGAAGATTTAGCTGACTTGGGAGATATCTCTCAAATGACTCCTGAAGACTTTTTCAAGAGCTT
AGAACAATCTATGCGAGAAAAAGGGGATGTTAATGCCCATGAGAAACTGGAAAAAATTGAAGAAATGATGGAAGATGTTG
TCGAAGCCACTCTAGCTAGTCAAACGGAAGAGACCGCTGAGGAAGTGGATCAAGAACCAGAGCCGTTAGATTACGTGCAT
TATGTTTTGGACTTTGCAACACTTTCAGAGGCCGTCGCTTTTTCTCAGACAATTGATTTTCCTGTTGAAGCTTCAGAATT
GTACAAAGGTGACAGCCGTTATCATATGACGATTTTATTAGATGTTCAGCAGCAACCATCTTATTTTGTTAATGTGATGT
ATGCAAGACTGATTGAGCATGCTAGTCCTGGAACAAAAACAAGAGCTTACTTACAAGAGCATGGCGTACAATTGATTCTG
GATGGGGCTGTTGAGCAATTACGAAAGATTGAGTTGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

64

98.814

0.632
  mecA Streptococcus thermophilus LMD-9

57.028

98.419

0.561
  mecA Streptococcus thermophilus LMG 18311

56.225

98.419

0.553
  mecA Streptococcus pneumoniae Rx1

47.843

100

0.482
  mecA Streptococcus pneumoniae D39

47.843

100

0.482
  mecA Streptococcus pneumoniae R6

47.843

100

0.482
  mecA Streptococcus pneumoniae TIGR4

47.843

100

0.482

Multiple sequence alignment