Detailed information NTG1120879

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: EL115_RS02740
• Genome accession: NZ_LR134307
• Coordinates: 530725..532875 (+)
• Length: 716 a.a.
• NCBI ID: WP_126441253.1
• Uniprot ID: -
• Organism: Streptococcus milleri strain NCTC10708
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 525725..537875

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL115_RS02705 (NCTC10708_00550)	pyrH	525748..526488 (+)	741	WP_003069937.1	UMP kinase	-
EL115_RS02710 (NCTC10708_00551)	frr	526492..527049 (+)	558	WP_003069936.1	ribosome recycling factor	-
EL115_RS02715 (NCTC10708_00552)	cvfB	527162..528016 (+)	855	WP_126441251.1	RNA-binding virulence regulatory protein CvfB	-
EL115_RS02720 (NCTC10708_00553)	holA	528097..529134 (+)	1038	WP_126441252.1	DNA polymerase III subunit delta	-
EL115_RS02725 (NCTC10708_00554)	-	529204..529809 (+)	606	WP_006267096.1	superoxide dismutase	-
EL115_RS02730 (NCTC10708_00555)	-	529865..530239 (-)	375	WP_003069929.1	hypothetical protein	-
EL115_RS02740 (NCTC10708_00556)	comA/nlmT	530725..532875 (+)	2151	WP_126441253.1	peptide cleavage/export ABC transporter	Regulator
EL115_RS02745 (NCTC10708_00557)	-	532886..534247 (+)	1362	WP_126441254.1	bacteriocin secretion accessory protein	-
EL115_RS02750 (NCTC10708_00558)	-	534341..534490 (+)	150	WP_003025431.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
EL115_RS02755 (NCTC10708_00559)	-	534535..535461 (-)	927	WP_126441255.1	GHKL domain-containing protein	-
EL115_RS02760 (NCTC10708_00560)	-	535693..535920 (+)	228	WP_004233901.1	bacteriocin	-
EL115_RS02765 (NCTC10708_00561)	-	535956..536276 (+)	321	WP_126441256.1	hypothetical protein	-
EL115_RS02770 (NCTC10708_00562)	-	536477..537535 (+)	1059	WP_039676806.1	thioredoxin family protein	-

Sequence

Protein

• Length: 716 a.a.
• Molecular weight: 80455.93 Da
• Isoelectric Point: 9.0896

>NTDB_id=1120879 EL115_RS02740 WP_126441253.1 530725..532875(+) (comA/nlmT) [Streptococcus milleri strain NCTC10708]
MNVKKTFVPQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTSKEGTTALGIVQAAQEIGFETRPIQGDMSLFDMEAIP
YPFIVHVQKKAKLPHYYVIYKNTKKGLLVGDPDPSVKITKISKETFATEWTGVAIFLAPEPSYKSHKDKKNGLTSFLPLI
FKQRSLIFYIVLASLLVTLINIVSSYYLQGILDEYIPNQMKSTLGIVSIGLIITYILQQMMSFSRDYLLIILSQRLTIDV
ILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDLFILIMVGGVLLLQNTNLFFLTLLAIPIYTVI
IFAFIKPFEKMNHDVMQSNSMVNSAIIEDINGIETIKSLTSEESCYQKIDSEFVDYLNKTFKLSKYSIMQTALKQGAQFI
LNVVILWVGASLAMSQKISIGQLITFNALLSYFTSPLESIINLQTKLQSAKVANNRLNEVYLVESEFKTKQVITEKNFLT
GDITFHNVSYKYGFGRDTLSDINLTIKIGDKVSLVGISGSGKTTLAKMMVHFYEPYKGQIRLNGNDLKMIDKKTLRQYIN
YLPQQAYIFSGSILENLTLGTNQIFSQEEIIRACEIAEIRSDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKSPI
LILDEATSGLDVLTEKKVIDNLMGLKDKTIIFVAHRLSISKRTNQVIVLDKGQIIETGSHAELMERQGFYHHLFNK

Nucleotide

• Length: 2151 bp

>NTDB_id=1120879 EL115_RS02740 WP_126441253.1 530725..532875(+) (comA/nlmT) [Streptococcus milleri strain NCTC10708]
GTGAATGTTAAGAAAACATTTGTTCCTCAAATAGATGCAAGAGATTGCGGTGTCGCTGCGCTGGCTTCCATTGCAAAATA
CTATGGTTCAGACTACTCTCTTGCACATCTGAGAGAACTTGCTAAGACAAGTAAAGAAGGGACAACGGCTCTTGGAATTG
TTCAAGCAGCACAAGAAATAGGCTTTGAGACACGACCGATTCAAGGGGATATGTCCTTGTTTGATATGGAAGCTATTCCC
TATCCTTTTATCGTTCATGTTCAGAAAAAAGCTAAACTCCCACATTATTATGTTATCTATAAAAATACGAAAAAAGGTCT
GCTAGTTGGAGATCCTGACCCAAGTGTAAAAATAACTAAGATATCAAAAGAAACATTTGCAACAGAATGGACTGGTGTTG
CTATTTTTTTAGCACCAGAACCTAGCTATAAATCACATAAGGATAAGAAGAATGGGCTTACTAGCTTTTTACCACTCATC
TTTAAACAGCGTTCTTTGATTTTTTATATTGTCTTAGCTAGTTTGCTTGTGACCCTCATCAACATTGTTAGTTCTTATTA
TCTGCAAGGGATTTTGGATGAATACATTCCAAATCAGATGAAATCAACTCTTGGAATCGTTTCAATTGGGCTTATCATTA
CTTACATCTTGCAGCAAATGATGAGTTTTTCCAGAGATTACTTATTGATTATACTTAGTCAGCGACTGACCATCGATGTA
ATTTTATCATATATTCGACACATTTTTGAATTACCGATGTCTTTTTTTGCTACGAGACGCACTGGAGAGATTATTTCTCG
TTTTACAGATGCTAATTCCATTATTGATGCTCTCGCTTCTACAATACTTTCACTCTTTCTTGACCTTTTTATTTTGATAA
TGGTAGGAGGGGTACTATTATTACAGAATACTAACCTTTTCTTCCTCACTCTGCTTGCTATTCCTATCTATACAGTGATT
ATTTTTGCTTTTATAAAGCCTTTTGAAAAAATGAATCATGACGTCATGCAAAGTAATTCCATGGTAAATTCTGCTATTAT
CGAAGATATTAATGGCATTGAAACGATTAAATCTTTAACCAGCGAAGAAAGTTGTTACCAAAAGATTGATAGTGAGTTTG
TCGATTATCTGAATAAGACTTTCAAGCTAAGTAAATATTCCATTATGCAGACAGCTCTCAAACAAGGAGCACAATTTATT
TTGAATGTTGTTATTCTATGGGTTGGAGCCTCTCTGGCTATGTCTCAAAAAATTTCGATTGGACAGCTGATTACTTTTAA
TGCACTCCTTTCGTATTTTACAAGTCCACTTGAAAGTATCATCAATCTGCAAACCAAGCTGCAATCGGCTAAGGTTGCCA
ACAATCGGTTGAATGAAGTCTATCTGGTAGAATCCGAATTCAAAACCAAACAAGTCATTACAGAGAAAAATTTCTTGACT
GGTGATATTACGTTCCATAATGTCTCCTATAAATACGGCTTCGGACGAGATACGTTATCGGATATTAACTTAACAATAAA
AATAGGAGATAAGGTGAGCTTAGTCGGTATCAGTGGTTCGGGAAAGACAACGCTTGCCAAAATGATGGTTCATTTTTATG
AGCCTTATAAAGGGCAAATCCGTCTCAATGGAAATGATCTTAAAATGATTGATAAGAAGACGCTTCGTCAATATATCAAT
TATTTACCACAACAAGCCTATATTTTTAGTGGTTCTATCTTAGAAAACCTTACATTAGGGACGAATCAAATATTTTCTCA
AGAAGAGATTATTCGCGCTTGTGAAATTGCAGAAATTCGTTCGGATATTGAACAAATGCCTATGGGATATCAAACAGAAT
TGTCCGATGGAGCTGGTCTATCAGGTGGACAAAAGCAAAGAATTGCTCTAGCACGAGCCCTCTTAACAAAGTCACCAATT
CTTATTCTTGATGAGGCAACGAGCGGATTGGATGTTCTAACTGAGAAAAAGGTCATTGACAATCTGATGGGCTTAAAAGA
CAAAACGATTATTTTTGTTGCTCATCGTCTCAGCATTTCAAAGCGGACAAATCAAGTGATTGTTCTTGATAAAGGGCAGA
TTATTGAAACTGGATCCCACGCTGAATTGATGGAAAGACAAGGCTTTTATCATCATTTATTTAATAAATAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (499-648)

• Peptidase C39 family (Peptidase_C39) (6-141)

• ABC transporter transmembrane region (ABC_membrane) (167-437)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	71.932	99.022	0.712
comA	Streptococcus mitis NCTC 12261	66.199	99.581	0.659
comA	Streptococcus mitis SK321	66.059	99.581	0.658
comA	Streptococcus pneumoniae D39	65.498	99.581	0.652
comA	Streptococcus pneumoniae Rx1	65.498	99.581	0.652
comA	Streptococcus pneumoniae R6	65.498	99.581	0.652
comA	Streptococcus gordonii str. Challis substr. CH1	65.358	99.581	0.651
comA	Streptococcus pneumoniae TIGR4	65.077	99.581	0.648