Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   EL115_RS02245 Genome accession   NZ_LR134307
Coordinates   432023..432697 (-) Length   224 a.a.
NCBI ID   WP_003070165.1    Uniprot ID   A0AAD2Y4E3
Organism   Streptococcus milleri strain NCTC10708     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 427023..437697
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL115_RS02215 (NCTC10708_00447) rsmD 427486..428034 (+) 549 WP_172594027.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  EL115_RS02220 (NCTC10708_00448) coaD 428024..428521 (+) 498 WP_003070176.1 pantetheine-phosphate adenylyltransferase -
  EL115_RS02225 (NCTC10708_00449) sepM 428502..429557 (+) 1056 WP_126441212.1 SepM family pheromone-processing serine protease Regulator
  EL115_RS02230 (NCTC10708_00450) - 429844..430401 (+) 558 WP_003070172.1 YutD family protein -
  EL115_RS02235 (NCTC10708_00451) rlmN 430435..431517 (+) 1083 WP_049476508.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  EL115_RS02240 (NCTC10708_00452) - 431510..432028 (+) 519 WP_126441213.1 VanZ family protein -
  EL115_RS02245 (NCTC10708_00453) cclA/cilC 432023..432697 (-) 675 WP_003070165.1 prepilin peptidase Machinery gene
  EL115_RS02250 (NCTC10708_00454) - 432848..433375 (+) 528 WP_003070162.1 Dps family protein -
  EL115_RS02255 (NCTC10708_00455) - 433640..433864 (+) 225 WP_003070161.1 YqgQ family protein -
  EL115_RS02260 (NCTC10708_00456) - 433858..434238 (+) 381 WP_126441214.1 rhodanese-like domain-containing protein -
  EL115_RS02265 (NCTC10708_00457) - 434259..434984 (-) 726 WP_126441215.1 16S rRNA pseudouridine(516) synthase -
  EL115_RS02270 (NCTC10708_00458) typA 435161..437002 (+) 1842 WP_006269878.1 translational GTPase TypA -
  EL115_RS02275 (NCTC10708_00459) - 437067..437345 (+) 279 WP_003070154.1 DUF3165 family protein -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25213.52 Da        Isoelectric Point: 8.3081

>NTDB_id=1120876 EL115_RS02245 WP_003070165.1 432023..432697(-) (cclA/cilC) [Streptococcus milleri strain NCTC10708]
MIHFYFFLVGSIVASFLGLVVDRFPEQSIITPASHCNVCGQKLAPRDLIPVLSQLINRLRCRFCNSKIPIRYILLELTGG
CLFLATSLGYLNINRLVLLAMGMTLSLYDQREQEYPLLIWLIFHIFLLFLTSFNLLMVAFLALGILAHFVDLRIGAGDFL
FLASCSTIFHLTEVLLIIQIASIIGLLLFGLKSKKDRLAFVPCLFCGSSILIMIQFIVLHQNAL

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1120876 EL115_RS02245 WP_003070165.1 432023..432697(-) (cclA/cilC) [Streptococcus milleri strain NCTC10708]
ATGATTCATTTTTATTTTTTCTTGGTTGGAAGTATTGTAGCTTCCTTTTTAGGACTGGTCGTTGATCGCTTTCCTGAGCA
GTCTATTATCACACCTGCTAGTCATTGCAACGTTTGTGGACAGAAATTAGCACCTCGTGATTTAATTCCTGTTCTTTCAC
AGCTTATCAATCGGCTGCGTTGCCGTTTTTGCAACTCAAAAATTCCCATCCGTTACATCCTTCTAGAACTAACTGGTGGC
TGTCTCTTTCTTGCAACATCTTTAGGTTATCTAAACATCAACCGGCTCGTTTTGCTTGCAATGGGAATGACCTTATCCCT
TTATGATCAAAGAGAACAAGAATATCCTCTCCTCATCTGGTTAATCTTTCATATTTTTCTCCTTTTTTTGACAAGCTTCA
ATCTTTTAATGGTTGCTTTTTTAGCACTTGGGATTTTGGCTCACTTCGTTGATTTACGTATCGGTGCAGGAGACTTTCTT
TTTCTGGCATCTTGCTCAACTATTTTTCATCTGACTGAAGTTCTTCTCATTATTCAAATTGCTAGTATCATTGGTCTGCT
CCTTTTTGGTTTAAAATCAAAAAAAGACAGGTTAGCCTTTGTTCCCTGTCTTTTCTGTGGTAGCAGCATCCTGATAATGA
TACAATTTATCGTTCTTCACCAAAATGCCTTATGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-87)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

58.491

94.643

0.554
  cclA/cilC Streptococcus mitis NCTC 12261

58.019

94.643

0.549
  cclA/cilC Streptococcus pneumoniae TIGR4

57.547

94.643

0.545
  cclA/cilC Streptococcus pneumoniae Rx1

57.075

94.643

0.54
  cclA/cilC Streptococcus pneumoniae D39

57.075

94.643

0.54
  cclA/cilC Streptococcus pneumoniae R6

57.075

94.643

0.54

Multiple sequence alignment