Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   EL115_RS02075 Genome accession   NZ_LR134307
Coordinates   398227..400110 (+) Length   627 a.a.
NCBI ID   WP_003070235.1    Uniprot ID   -
Organism   Streptococcus milleri strain NCTC10708     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 393227..405110
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL115_RS02060 (NCTC10708_00415) fmt 395233..396168 (+) 936 WP_003070241.1 methionyl-tRNA formyltransferase -
  EL115_RS02065 (NCTC10708_00416) rsmB 396158..397471 (+) 1314 WP_003070239.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  EL115_RS02070 (NCTC10708_00417) - 397490..398230 (+) 741 WP_003028411.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  EL115_RS02075 (NCTC10708_00418) stkP 398227..400110 (+) 1884 WP_003070235.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  EL115_RS02080 (NCTC10708_00419) liaF 400367..401065 (+) 699 WP_003070232.1 cell wall-active antibiotics response protein LiaF -
  EL115_RS02085 (NCTC10708_00420) - 401062..402057 (+) 996 WP_126441200.1 sensor histidine kinase -
  EL115_RS02090 (NCTC10708_00421) - 402059..402691 (+) 633 WP_003070225.1 response regulator transcription factor -
  EL115_RS02095 (NCTC10708_00422) - 402738..404138 (+) 1401 WP_126441201.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  EL115_RS02100 (NCTC10708_00423) - 404140..404532 (+) 393 WP_014829583.1 S1 RNA-binding domain-containing protein -
  EL115_RS02105 (NCTC10708_00424) - 404652..404969 (-) 318 WP_102567839.1 DUF960 domain-containing protein -

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 68065.30 Da        Isoelectric Point: 9.5690

>NTDB_id=1120872 EL115_RS02075 WP_003070235.1 398227..400110(+) (stkP) [Streptococcus milleri strain NCTC10708]
MIQVGKIFAGRYRIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKEHAPLSNEEAVRIMGQILLAMRLAHTHGIVHRDLKPQNVLLTPDGDAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPNVP
QPLENVVIKATAKKLTDRYQSVAEMYVDLSSCLSADRRNEKKLVFDDTAKADTKTLPKVSQNTLISASKPTTPTPIKETV
SSNSKPTTKPKTKKKRRLRTRYKVLLSAVVLVIAALVALVYLSPSNVKIPDVTGKTVAQARSAIETAGLKVGKEKDEYSD
SVKKDSVIRTNPEAGTQRRDGSTVDLIVSKGTKTFIMEDYKGQKRADAINNLVQKYKVSKGLIKTEEVESSEHAAGTVVG
QTPAAGSTYDLTSKARITLKVAKSVSSVVMPSYIGSTYEFAYNNLTQVLGIQGANIEKRTVPTAPAGTQANTIIKQTPEA
NQSLDLKSDRIVLYVYEPKTESSSTSESSLQSESSSEKNSPSSSNSSTSGNDGSSSKTPDTSASASN

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=1120872 EL115_RS02075 WP_003070235.1 398227..400110(+) (stkP) [Streptococcus milleri strain NCTC10708]
ATGATTCAAGTCGGCAAAATATTTGCCGGGCGATATAGAATCATCAAACAAATTGGGCGAGGTGGCATGGCAGATGTTTA
CTTGGCCAAAGATTTGATTTTAGACGGGGAAGAAGTCGCGGTGAAAGTTCTAAGAACGAATTACCAGACGGATCCGATTG
CTGTGGCACGCTTTCAAAGAGAGGCGCGAGCGATGGCAGACTTGGATCATCCTCATATTGTCCGGATTACCGATATTGGA
GAAGAAGAAGGTCAGCAATATCTAGCAATGGAGTATGTGGCTGGGCTTGACTTAAAACGCTATATTAAAGAGCATGCTCC
TTTATCTAATGAAGAAGCGGTTCGGATTATGGGACAAATTCTTTTGGCAATGCGTTTGGCGCATACGCATGGAATTGTTC
ATCGTGATTTGAAGCCACAAAATGTCCTTTTAACTCCAGATGGCGATGCAAAAGTAACGGACTTTGGAATTGCAGTAGCT
TTTGCAGAAACGAGTTTAACCCAGACAAATTCAATGCTGGGATCTGTGCATTATCTATCACCAGAACAAGCGCGTGGTTC
AAAAGCGACCGTTCAAAGCGATATTTACGCTATGGGGATCATTTTCTATGAAATGTTGACAGGACATATCCCTTATGATG
GGGATAGTGCTGTCACAATTGCTTTGCAACATTTCCAAAAGCCTCTTCCTTCTGTGATTGCTGAAAATCCAAATGTGCCA
CAGCCTCTAGAAAATGTAGTCATCAAGGCAACGGCTAAAAAATTAACAGATCGTTATCAATCTGTTGCAGAAATGTATGT
GGATTTATCAAGCTGCTTATCCGCAGATCGCCGAAATGAGAAAAAGTTGGTTTTTGATGATACTGCCAAAGCAGACACCA
AAACGCTTCCTAAAGTGTCACAAAATACCTTAATTTCTGCAAGCAAACCAACTACTCCTACGCCTATAAAAGAAACAGTC
AGTAGTAATTCTAAACCCACAACCAAGCCAAAAACAAAGAAAAAGCGTCGTTTAAGAACGCGTTATAAGGTTCTGTTGTC
GGCAGTAGTTTTAGTGATTGCTGCTCTGGTGGCATTAGTCTATTTGAGTCCGTCAAATGTAAAAATTCCAGACGTTACTG
GAAAAACTGTTGCACAAGCTCGTTCTGCAATTGAAACAGCAGGTTTGAAAGTTGGTAAGGAAAAAGATGAATATAGCGAC
TCTGTCAAAAAGGATTCTGTTATTCGCACCAATCCAGAAGCGGGAACACAGCGTCGCGACGGAAGCACGGTGGATCTGAT
TGTTTCCAAAGGTACAAAAACCTTTATTATGGAAGATTATAAAGGTCAGAAAAGAGCGGATGCTATCAACAATCTAGTCC
AAAAATACAAGGTTTCAAAAGGTTTAATTAAAACAGAAGAAGTTGAAAGTAGTGAGCATGCGGCTGGAACAGTCGTTGGT
CAAACGCCAGCAGCAGGTAGTACATATGATTTGACTTCAAAAGCTCGTATTACTTTGAAAGTAGCCAAGTCCGTTTCAAG
TGTTGTCATGCCAAGTTATATCGGTTCAACCTATGAATTTGCCTATAACAATTTAACGCAAGTGCTTGGCATTCAAGGTG
CTAATATTGAAAAACGAACGGTTCCAACAGCTCCGGCTGGAACACAAGCAAATACGATTATTAAACAAACACCAGAAGCA
AATCAGTCCTTGGATTTGAAGAGCGACCGCATTGTCCTATATGTATATGAGCCGAAAACCGAAAGTTCATCTACATCTGA
AAGTAGTTTGCAATCTGAAAGTAGTTCAGAAAAAAATAGTCCATCGTCTAGTAACTCATCAACTAGTGGTAATGATGGTT
CAAGTTCAAAAACGCCAGACACAAGTGCTAGTGCAAGCAATTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(436-503)

PASTA domain (PASTA)

(367-430)

PASTA domain (PASTA)

(508-576)

Protein kinase domain (Pkinase)

(12-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

65.588

93.62

0.614
  stkP Streptococcus pneumoniae D39

65.247

93.62

0.611
  stkP Streptococcus pneumoniae R6

65.247

93.62

0.611
  stkP Streptococcus pneumoniae Rx1

65.077

93.62

0.609
  pknB Streptococcus mutans UA159

58.974

93.301

0.55
  stkP/pknB Streptococcus salivarius strain HSISS4

55.184

95.375

0.526

Multiple sequence alignment