Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   EL114_RS01795 Genome accession   NZ_LR134297
Coordinates   385109..386395 (-) Length   428 a.a.
NCBI ID   WP_126343035.1    Uniprot ID   -
Organism   Enterococcus hirae strain NCTC12368     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 380109..391395
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL114_RS01770 (NCTC12368_00363) - 381154..381507 (-) 354 WP_002317104.1 PepSY domain-containing protein -
  EL114_RS01775 (NCTC12368_00364) pepA 381706..382785 (+) 1080 WP_010720947.1 glutamyl aminopeptidase -
  EL114_RS01780 (NCTC12368_00365) - 383319..383639 (+) 321 WP_126343029.1 thioredoxin family protein -
  EL114_RS01785 (NCTC12368_00366) - 383669..384136 (+) 468 WP_126343032.1 universal stress protein -
  EL114_RS01790 (NCTC12368_00367) ytpR 384446..385051 (+) 606 WP_010737044.1 YtpR family tRNA-binding protein -
  EL114_RS01795 (NCTC12368_00368) htrA 385109..386395 (-) 1287 WP_126343035.1 S1C family serine protease Regulator
  EL114_RS01800 (NCTC12368_00369) rlmH 386848..387327 (+) 480 WP_126343038.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  EL114_RS01805 (NCTC12368_00370) - 387412..387921 (+) 510 WP_002296569.1 DUF1456 family protein -
  EL114_RS01810 (NCTC12368_00371) - 388021..388671 (+) 651 WP_002312640.1 hypothetical protein -
  EL114_RS01815 (NCTC12368_00372) - 389122..390060 (+) 939 WP_002291914.1 2-dehydropantoate 2-reductase -
  EL114_RS01820 (NCTC12368_00373) - 390073..391125 (+) 1053 WP_002291912.1 PTS sugar transporter subunit IIC -

Sequence

Protein


Download         Length: 428 a.a.        Molecular weight: 44595.70 Da        Isoelectric Point: 4.7976

>NTDB_id=1120654 EL114_RS01795 WP_126343035.1 385109..386395(-) (htrA) [Enterococcus hirae strain NCTC12368]
MERKDVTPKMKKNNGIWRKLGLGLVGGIIGGLVTAGIFYAVMGSGNAASNSGGHQNSAGETVVENVKVNVDSDITNAVDK
VQDAVVSVINLQSQNQGTNGFGQLFGQQQQESSDDSNLEASSEGSGVIYKKSGNSAYIVTNNHVVEGQQGLEVLLKDGTK
VKAELVGTDAYSDLAVLKISADKVNKVASFGDSNSLKVGEPAIAIGSPLGSEYANSVTSGIISSLNRQVTSTNESNQTVN
INAIQTDAAINPGNSGGPLVNIEGQVIGINSSKIASTSASSSGVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITM
VDLSAISTQQQEQILKIPESVTNGVIVTSVQPATPAEKAGLKQYDVITKIDDTDVSSGVELQSVLYQKKVGDSVKVTYYR
GKEKKTTTIQLTIDQSALKQSQSENSGN

Nucleotide


Download         Length: 1287 bp        

>NTDB_id=1120654 EL114_RS01795 WP_126343035.1 385109..386395(-) (htrA) [Enterococcus hirae strain NCTC12368]
ATGGAGAGAAAAGATGTGACACCAAAAATGAAAAAGAATAATGGAATCTGGCGTAAGCTGGGTCTAGGCTTAGTCGGTGG
AATTATTGGGGGCTTGGTAACGGCTGGTATTTTTTATGCTGTCATGGGTTCTGGAAACGCAGCGTCAAATTCGGGTGGTC
ATCAAAATTCAGCGGGCGAAACTGTCGTTGAAAATGTCAAAGTCAATGTCGATTCAGATATCACGAATGCGGTCGATAAA
GTCCAAGATGCGGTGGTATCTGTTATCAATCTTCAAAGCCAAAATCAAGGGACCAACGGCTTTGGGCAACTGTTTGGTCA
ACAACAACAAGAAAGTTCTGATGATAGCAATCTAGAGGCTTCTAGTGAAGGTAGTGGTGTCATCTACAAAAAAAGCGGTA
ATTCCGCTTATATCGTAACGAATAATCACGTAGTGGAAGGACAACAAGGATTAGAAGTTTTATTAAAAGATGGAACAAAA
GTCAAAGCTGAATTAGTCGGGACGGATGCTTATTCTGACTTAGCCGTTTTGAAAATCAGTGCAGATAAAGTGAACAAAGT
TGCTTCATTTGGTGACTCTAATTCATTGAAAGTAGGAGAACCGGCGATCGCAATTGGTTCTCCTCTAGGTTCTGAATATG
CCAACTCTGTGACTTCGGGGATTATCTCTTCATTGAATCGCCAAGTAACCAGCACGAACGAGTCAAATCAAACGGTCAAT
ATCAATGCGATCCAAACAGATGCTGCGATTAACCCTGGTAATTCTGGTGGTCCATTAGTTAATATTGAAGGTCAAGTGAT
CGGGATCAATTCAAGTAAAATTGCAAGTACTTCTGCTTCTTCATCAGGTGTAAGCGTGGAAGGAATGGGCTTTGCGATCC
CAAGTAACGATGTAGTAAATATTATCAACCAACTTGAAAAAGATGGAAAAGTAACCCGTCCTGCTCTAGGGATCACAATG
GTTGACCTTTCAGCCATTTCAACCCAACAACAAGAACAAATCTTGAAAATTCCTGAATCTGTGACAAATGGTGTGATTGT
TACCAGCGTTCAACCGGCGACACCTGCAGAAAAAGCTGGCTTGAAACAATATGATGTCATTACAAAAATCGATGATACTG
ATGTTTCTTCTGGTGTAGAATTACAATCTGTCTTGTATCAGAAAAAAGTCGGCGATTCAGTGAAGGTCACTTACTATCGC
GGAAAAGAAAAGAAAACAACAACAATTCAATTAACAATTGATCAATCCGCATTAAAACAAAGCCAATCAGAGAACTCTGG
TAACTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(314-411)

Trypsin-like peptidase domain (Trypsin_2)

(124-269)

Peptidase family M50 (Peptidase_M50)

(12-415)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

54.545

92.523

0.505
  htrA Streptococcus gordonii str. Challis substr. CH1

53.35

94.159

0.502
  htrA Streptococcus pneumoniae Rx1

58.16

78.738

0.458
  htrA Streptococcus pneumoniae D39

58.16

78.738

0.458
  htrA Streptococcus pneumoniae R6

58.16

78.738

0.458
  htrA Streptococcus pneumoniae TIGR4

58.16

78.738

0.458
  htrA Streptococcus mitis NCTC 12261

57.864

78.738

0.456

Multiple sequence alignment