Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   EL096_RS05855 Genome accession   NZ_LR134294
Coordinates   1116465..1118444 (-) Length   659 a.a.
NCBI ID   WP_050221291.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NCTC12977     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1111465..1123444
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL096_RS05825 (NCTC12977_01141) - 1111561..1112835 (-) 1275 WP_114880763.1 hydroxymethylglutaryl-CoA reductase, degradative -
  EL096_RS05830 (NCTC12977_01142) - 1112835..1114007 (-) 1173 WP_000151960.1 hydroxymethylglutaryl-CoA synthase -
  EL096_RS05835 - 1114138..1114386 (-) 249 Protein_1113 hypothetical protein -
  EL096_RS05840 - 1114454..1115079 (-) 626 Protein_1114 transposase -
  EL096_RS05845 (NCTC12977_01144) - 1115141..1115590 (-) 450 WP_000176924.1 threonine/serine exporter family protein -
  EL096_RS05850 (NCTC12977_01145) - 1115592..1116350 (-) 759 WP_000392880.1 threonine/serine exporter family protein -
  EL096_RS05855 (NCTC12977_01146) stkP 1116465..1118444 (-) 1980 WP_050221291.1 serine/threonine-protein kinase StkP Regulator
  EL096_RS05860 (NCTC12977_01147) - 1118441..1119181 (-) 741 WP_000406247.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  EL096_RS05865 (NCTC12977_01148) rsmB 1119196..1120509 (-) 1314 WP_001812782.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  EL096_RS05870 (NCTC12977_01149) fmt 1120502..1121437 (-) 936 WP_050221290.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 659 a.a.        Molecular weight: 72230.77 Da        Isoelectric Point: 9.2260

>NTDB_id=1120549 EL096_RS05855 WP_050221291.1 1116465..1118444(-) (stkP) [Streptococcus pneumoniae strain NCTC12977]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPGGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYNRRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIK
NPSQAVTEETYQPQAPKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANFEIGEEKTE
ASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSDVIAELKEKKVPDNLIKIEEEESNESEAGTV
LKQSLPEGTTYDLSKATQIVLTVAKKATTIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAG
TTYDVSKPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAEGMVVEQSPRAGEKVDL
NKTRVKISIYKPKTTSATP

Nucleotide


Download         Length: 1980 bp        

>NTDB_id=1120549 EL096_RS05855 WP_050221291.1 1116465..1118444(-) (stkP) [Streptococcus pneumoniae strain NCTC12977]
ATGATCCAAATCGGCAAGATTTTTGCCGGACGCTATCGGATTGTCAAACAGATTGGTCGAGGAGGCATGGCGGATGTCTA
CCTAGCCAAAGACTTAATCTTAGATGGGGAAGAAGTGGCAGTGAAGGTTCTGAGGACCAACTACCAGACGGACCCGATAG
CTGTAGCTCGTTTTCAGCGTGAAGCGAGAGCTATGGCAGATCTAGACCATCCTCATATCGTTCGGATAACAGATATTGGT
GAGGAAGACGGTCAACAGTATCTTGCAATGGAGTATGTTGCTGGACTAGACCTCAAACGCTATATCAAGGAACATTATCC
TCTTTCTAATGAAGAAGCAGTCCGTATCATGGGACAAATTCTCTTGGCTATGCGCTTGGCCCATACTCGAGGAATTGTTC
ACAGGGACTTGAAACCTCAAAATATCCTTTTGACACCAGGTGGGACTGCCAAGGTCACAGACTTTGGGATTGCTGTAGCC
TTTGCAGAGACAAGTCTGACCCAGACTAACTCGATGTTGGGCTCAGTTCATTACTTGTCACCAGAGCAGGCGCGTGGTTC
GAAGGCGACTGTGCAGAGTGATATCTATGCCATGGGGATTATTTTCTATGAGATGTTGACAGGCCATATCCCTTATGACG
GGGATAGCGCGGTGACCATTGCCCTCCAGCATTTCCAGAAACCCCTGCCGTCCGTTATTGCAGAAAATCCATCTGTACCT
CAGGCTTTAGAAAATGTTATTATCAAGGCAACTGCTAAAAAGTTGACCAATCGCTACCGCTCGGTTTCAGAGATGTATGT
GGACTTGTCTAGTAGCTTGTCCTACAATCGTAGAAATGAAAGTAAGTTAATCTTTGATGAAACGAGCAAGGCAGATACCA
AGACCTTGCCGAAGGTTTCTCAGAGTACCTTGACATCTATTCCTAAGGTTCAAGCGCAGACAGAACACAAATCAATCAAA
AACCCAAGCCAGGCTGTGACAGAGGAAACTTACCAACCACAAGCACCGAAAAAACATAGATTTAAGATGCGTTACCTGAT
TTTGTTGGCCAGCCTTGTATTGGTGGCAGCTTCTCTTATTTGGATACTATCCAGAACTCCTGCAACCATTGCCATTCCAG
ATGTGGCAGGTCAGACAGTTGCAGAGGCCAAGGCAACGCTCAAAAAAGCCAATTTTGAGATTGGTGAGGAGAAGACAGAG
GCTAGTGAAAAGGTGGAAGAAGGGCGGATTATCCGTACAGATCCTGGCGCTGGAACTGGTCGAAAAGAAGGAACGAAAAT
CAATCTGGTTGTCTCATCAGGCAAACAATCCTTCCAAATTAGTAATTATGTCGGCCGGAAATCTTCTGATGTTATCGCGG
AATTAAAAGAGAAAAAAGTTCCAGATAATTTGATTAAAATTGAGGAAGAAGAGTCGAATGAGAGTGAGGCTGGAACGGTC
TTGAAGCAAAGTCTACCAGAAGGTACGACCTATGACTTGAGCAAGGCAACTCAAATTGTTTTGACAGTAGCTAAAAAAGC
TACGACGATTCAATTAGGGAACTATATTGGACGGAACTCTACAGAAGTAATCTCAGAACTTAAGCAGAAGAAGGTTCCTG
AGAATTTGATTAAGATAGAGGAAGAAGAGTCCAGCGAAAGCGAACCAGGAACGATTATGAAACAAAGTCCAGGTGCCGGA
ACGACTTATGATGTGAGTAAACCTACTCAAATTGTCTTGACAGTAGCTAAAAAAGTTACAAGTGTTGCCATGCCGAGTTA
CATTGGTTCCAGCTTGGAGTTTACTAAGAACAATTTGATTCAAATTGTTGGGATTAAGGAAGCTAATATAGAAGTTGTAG
AAGTGACGACAGCGCCTGCAGGTAGTGCAGAAGGCATGGTTGTTGAACAAAGTCCTAGAGCAGGTGAAAAGGTAGACCTC
AATAAGACTAGAGTCAAGATTTCAATCTACAAACCTAAAACAACTTCAGCTACTCCTTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-227)

PASTA domain (PASTA)

(440-505)

PASTA domain (PASTA)

(582-651)

PASTA domain (PASTA)

(513-577)

PASTA domain (PASTA)

(371-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

99.848

100

0.998
  stkP Streptococcus pneumoniae D39

99.393

100

0.994
  stkP Streptococcus pneumoniae R6

99.393

100

0.994
  stkP Streptococcus pneumoniae Rx1

99.241

100

0.992
  pknB Streptococcus mutans UA159

52.479

88.771

0.466
  stkP/pknB Streptococcus salivarius strain HSISS4

51.635

88.164

0.455

Multiple sequence alignment