Detailed information NTG1120494

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: EL097_RS02695
• Genome accession: NZ_LR134293
• Coordinates: 521111..522022 (-)
• Length: 303 a.a.
• NCBI ID: WP_003046007.1
• Uniprot ID: A0AAE4Q9F2
• Organism: Streptococcus canis strain NCTC12191
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 516111..527022

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL097_RS02675 (NCTC12191_00524)	-	517118..518893 (-)	1776	WP_003046018.1	acyltransferase family protein	-
EL097_RS02680 (NCTC12191_00525)	-	518890..519291 (-)	402	WP_003046016.1	MORN repeat-containing protein	-
EL097_RS02685 (NCTC12191_00526)	-	519308..519751 (-)	444	WP_129544930.1	low molecular weight protein-tyrosine-phosphatase	-
EL097_RS02690 (NCTC12191_00527)	ruvB	519892..520890 (-)	999	WP_003046011.1	Holliday junction branch migration DNA helicase RuvB	-
EL097_RS10825 (NCTC12191_00528)	comS	520923..521024 (-)	102	WP_201281440.1	quorum-sensing system DWW-type pheromone	Regulator
EL097_RS02695 (NCTC12191_00529)	comR	521111..522022 (-)	912	WP_003046007.1	helix-turn-helix domain-containing protein	Regulator
EL097_RS02700 (NCTC12191_00530)	purB	522159..523451 (-)	1293	WP_003046005.1	adenylosuccinate lyase	-
EL097_RS02705 (NCTC12191_00531)	purK	523969..525039 (-)	1071	WP_003046003.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
EL097_RS02710 (NCTC12191_00532)	purE	525026..525517 (-)	492	WP_003046002.1	5-(carboxyamino)imidazole ribonucleotide mutase	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 36092.66 Da
• Isoelectric Point: 5.0503

>NTDB_id=1120494 EL097_RS02695 WP_003046007.1 521111..522022(-) (comR) [Streptococcus canis strain NCTC12191]
MLEHFGEKVKGLRQEKKISREDLCGDESELSVRQLARIELSQSIPSLAKVIFIAKALDVSVGYLTDGANLELPKRYKELK
YLILRTPTYMDDGKLQVREEQFDEIFEDYYDQLPEEEQVAIDIIQAKFEVYQTGNINFGSSILKEFLPQLKRKVIYNLNE
LLLIDLYLVTLVVSHFADDLFDRELYNKITERILKQNHHLMLEDLFLLNNILLSCADTSIRLEMFGRLKETLQLSHFIMS
TIQDFQRMPIYCMYEWKLSIFYLKDVERARNYYEQSILFTQMTSDYYLVERLHKEWHKDIQHI

Nucleotide

• Length: 912 bp

>NTDB_id=1120494 EL097_RS02695 WP_003046007.1 521111..522022(-) (comR) [Streptococcus canis strain NCTC12191]
ATGTTAGAGCATTTTGGTGAAAAAGTGAAAGGGCTAAGACAAGAGAAAAAGATTAGCAGAGAAGACTTATGTGGGGATGA
GTCTGAATTATCTGTTCGTCAACTAGCGAGGATTGAGTTGAGCCAGTCTATACCAAGTTTAGCCAAGGTTATTTTTATTG
CAAAAGCCTTAGATGTTAGCGTAGGTTATTTGACTGATGGGGCCAACCTTGAGTTACCCAAACGTTACAAAGAGTTAAAA
TATTTAATTCTGCGGACGCCAACTTATATGGATGATGGCAAATTACAAGTTCGAGAAGAACAGTTTGATGAGATATTTGA
GGATTACTATGACCAGCTGCCTGAGGAGGAGCAGGTGGCTATTGATATTATTCAAGCAAAATTTGAAGTTTACCAAACTG
GGAATATTAATTTTGGATCTAGTATTTTAAAAGAATTTTTACCACAACTTAAAAGGAAAGTTATTTATAATTTAAATGAG
TTGCTTTTGATAGATTTGTATTTAGTTACTTTGGTGGTTTCCCATTTTGCAGATGATTTATTTGACAGAGAGCTTTATAA
TAAGATTACAGAAAGAATTTTAAAACAAAACCATCATTTAATGTTGGAAGATTTATTTCTGCTGAATAATATTTTATTGT
CTTGTGCAGATACCTCTATTCGTTTAGAAATGTTTGGGAGGCTAAAAGAGACGTTACAACTCAGTCATTTCATTATGTCA
ACTATTCAAGATTTTCAAAGAATGCCAATTTATTGTATGTATGAGTGGAAGTTATCTATCTTTTATTTAAAAGATGTTGA
ACGTGCTCGAAATTATTATGAACAATCTATTTTATTTACTCAAATGACTAGTGATTATTACCTGGTTGAGAGACTTCACA
AAGAATGGCATAAAGATATTCAACATATATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (12-64)

• ComR tetratricopeptide (ComR_TPR) (73-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS315	84.818	100	0.848
comR	Streptococcus pyogenes MGAS8232	55.629	99.67	0.554
comR	Streptococcus mutans UA159	48.344	99.67	0.482
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	44.746	97.36	0.436