Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   EL097_RS01090 Genome accession   NZ_LR134293
Coordinates   216216..216977 (-) Length   253 a.a.
NCBI ID   WP_003046641.1    Uniprot ID   A0AAE4TTC6
Organism   Streptococcus canis strain NCTC12191     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 211216..221977
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL097_RS01070 (NCTC12191_00209) - 211528..212754 (-) 1227 WP_003046653.1 cysteine desulfurase -
  EL097_RS01075 (NCTC12191_00210) sufD 212785..214047 (-) 1263 WP_003046650.1 Fe-S cluster assembly protein SufD -
  EL097_RS01080 (NCTC12191_00211) sufC 214146..214916 (-) 771 WP_129544908.1 Fe-S cluster assembly ATPase SufC -
  EL097_RS01085 (NCTC12191_00212) - 215040..216209 (-) 1170 WP_039994771.1 glycosyltransferase family 4 protein -
  EL097_RS01090 (NCTC12191_00213) mecA 216216..216977 (-) 762 WP_003046641.1 adaptor protein MecA Regulator
  EL097_RS01095 (NCTC12191_00214) - 217121..217960 (-) 840 WP_003046638.1 undecaprenyl-diphosphate phosphatase -
  EL097_RS01100 (NCTC12191_00215) - 218338..219906 (+) 1569 WP_003046635.1 ABC transporter substrate-binding protein/permease -
  EL097_RS01105 (NCTC12191_00216) - 219899..220639 (+) 741 WP_003046632.1 amino acid ABC transporter ATP-binding protein -
  EL097_RS01110 (NCTC12191_00217) - 220780..220896 (+) 117 WP_003046630.1 putative metal homeostasis protein -
  EL097_RS01115 (NCTC12191_00218) - 221035..221925 (-) 891 WP_003046627.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29216.90 Da        Isoelectric Point: 4.0845

>NTDB_id=1120483 EL097_RS01090 WP_003046641.1 216216..216977(-) (mecA) [Streptococcus canis strain NCTC12191]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEL
NKELNFEDLADLGDISQMTPEDFFKSLEQSMREKGDVNAHEKLEKIEEIMEDVVEATLTGQAEATDETHEVDPEPLDYVH
YVLDFDTLPEAITFAKTIDFPIEASELYKGDSRYHMTILLDVQQQPSYFANVMYARLIEYATPGSKTRAYLQEHGLQLIL
DGAVEQLRKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=1120483 EL097_RS01090 WP_003046641.1 216216..216977(-) (mecA) [Streptococcus canis strain NCTC12191]
ATGGAAATGAAACAAATTAGCGAGACAACGCTGAAAATAACAATTAGTATGGATGATTTAGAAGAAAGAGGAATGGAGTT
AAAAGATTTTCTCATTCCCCAAGAAAAAACGGAAGAGTTCTTTTATTCTGTTATGGATGAACTAGATCTTCCAGATAATT
TTAAAGATAGTGGCATGCTTAGTTTTCGAGTAACACCAAGAAAAGACCGGCTAGATGTTTTTGTAACCAAATCTGAGCTT
AATAAGGAGCTTAACTTTGAAGATTTGGCAGATTTGGGTGATATTTCTCAAATGACACCTGAAGATTTTTTCAAAAGTTT
GGAGCAATCCATGCGTGAAAAAGGGGATGTCAATGCGCATGAGAAATTGGAAAAAATTGAAGAAATCATGGAAGACGTGG
TCGAAGCAACCTTAACTGGTCAGGCTGAGGCAACAGATGAAACGCATGAGGTCGATCCAGAACCATTGGATTATGTGCAC
TATGTTTTGGACTTTGATACCCTTCCAGAGGCGATAACCTTCGCCAAAACCATTGATTTCCCTATTGAAGCTTCAGAATT
ATACAAGGGTGACAGCCGTTACCACATGACCATTTTATTGGACGTTCAACAGCAGCCGTCATATTTTGCGAATGTTATGT
ATGCAAGGTTAATTGAGTATGCAACCCCTGGGTCAAAAACAAGAGCCTACTTGCAAGAGCATGGCTTACAATTGATTCTA
GATGGCGCTGTTGAGCAATTACGAAAGATTGAGTTGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

62.8

98.814

0.621
  mecA Streptococcus thermophilus LMD-9

56.225

98.419

0.553
  mecA Streptococcus thermophilus LMG 18311

55.823

98.419

0.549
  mecA Streptococcus pneumoniae TIGR4

48.221

100

0.482
  mecA Streptococcus pneumoniae Rx1

47.826

100

0.478
  mecA Streptococcus pneumoniae D39

47.826

100

0.478
  mecA Streptococcus pneumoniae R6

47.826

100

0.478

Multiple sequence alignment