Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   EL084_RS03965 Genome accession   NZ_LR134292
Coordinates   801429..802103 (-) Length   224 a.a.
NCBI ID   WP_004231785.1    Uniprot ID   E8JND8
Organism   Streptococcus equinus strain NCTC10389     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 796429..807103
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL084_RS03940 (NCTC10389_00831) - 796738..797328 (-) 591 WP_126440222.1 class I SAM-dependent methyltransferase -
  EL084_RS03945 (NCTC10389_00832) coaA 797442..798362 (+) 921 WP_004231766.1 type I pantothenate kinase -
  EL084_RS03950 (NCTC10389_00833) rpsT 798438..798689 (+) 252 WP_004231769.1 30S ribosomal protein S20 -
  EL084_RS03955 (NCTC10389_00834) - 798898..800076 (+) 1179 WP_126440223.1 ISL3 family transposase -
  EL084_RS03960 (NCTC10389_00835) ciaH 800114..801439 (-) 1326 WP_126440224.1 sensor histidine kinase Regulator
  EL084_RS03965 (NCTC10389_00836) ciaR 801429..802103 (-) 675 WP_004231785.1 response regulator transcription factor Regulator
  EL084_RS03970 (NCTC10389_00837) - 802256..804799 (-) 2544 WP_126440225.1 M1 family metallopeptidase -
  EL084_RS03975 (NCTC10389_00838) phoU 805008..805661 (-) 654 WP_126440226.1 phosphate signaling complex protein PhoU -
  EL084_RS03980 (NCTC10389_00839) pstB 805693..806451 (-) 759 WP_004231792.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25393.04 Da        Isoelectric Point: 4.3369

>NTDB_id=1120439 EL084_RS03965 WP_004231785.1 801429..802103(-) (ciaR) [Streptococcus equinus strain NCTC10389]
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGAEGLYEAESGVYDLILLDLMLPEKDGFQILKELREKCVSTPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFNNNTLSYHELTADTSTNTTTVNGEKVELLGKEFDLLVY
FLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTSFADSLQTLRSVGYILKDAE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1120439 EL084_RS03965 WP_004231785.1 801429..802103(-) (ciaR) [Streptococcus equinus strain NCTC10389]
ATGATTAAAATTTTATTAGTAGAAGATGATTTGAGCTTGTCGAATTCAATTTTTGATTTTTTGGATGATTTTGCGGATGT
CATGCAGGTTTTTGACGGCGCAGAAGGCTTGTACGAAGCAGAAAGTGGTGTTTATGACCTTATTTTGCTTGATTTGATGT
TGCCAGAAAAAGATGGTTTCCAGATTCTTAAAGAATTACGTGAAAAATGCGTTTCAACACCTGTTTTGATTATGACAGCT
AAAGAAAGTCTTGATGATAAAGGGCACGGATTCGAATTAGGTGCTGATGATTACCTAACAAAACCATTTTATCTTGAAGA
GCTTAAGATGCGTATTCAAGCTCTTTTAAAACGTTCAGGTAAATTTAATAACAATACTTTGTCATATCATGAATTAACTG
CGGATACTTCAACAAATACAACAACTGTTAATGGTGAAAAAGTTGAATTACTAGGTAAAGAGTTTGATTTGTTAGTATAC
TTTTTGCAAAACCAAAATGTCATTTTGCCAAAATCACAAATTTTTGACCGTATTTGGGGCTTTGATAGCGATACTACAAT
TTCAGTTGTTGAAGTATACGTTTCAAAAATTCGTAAAAAACTCAAAGGCACTAGTTTTGCCGATAGTCTTCAAACACTAC
GTAGTGTAGGTTACATATTGAAAGATGCTGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB E8JND8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

90.135

99.554

0.897
  ciaR Streptococcus pneumoniae Rx1

85.714

100

0.857
  ciaR Streptococcus pneumoniae D39

85.714

100

0.857
  ciaR Streptococcus pneumoniae R6

85.714

100

0.857
  ciaR Streptococcus pneumoniae TIGR4

85.714

100

0.857
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.326

100

0.388

Multiple sequence alignment