Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   EL084_RS03960 Genome accession   NZ_LR134292
Coordinates   800114..801439 (-) Length   441 a.a.
NCBI ID   WP_126440224.1    Uniprot ID   -
Organism   Streptococcus equinus strain NCTC10389     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 795114..806439
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL084_RS03935 (NCTC10389_00830) deoC 795571..796236 (-) 666 WP_004231760.1 deoxyribose-phosphate aldolase -
  EL084_RS03940 (NCTC10389_00831) - 796738..797328 (-) 591 WP_126440222.1 class I SAM-dependent methyltransferase -
  EL084_RS03945 (NCTC10389_00832) coaA 797442..798362 (+) 921 WP_004231766.1 type I pantothenate kinase -
  EL084_RS03950 (NCTC10389_00833) rpsT 798438..798689 (+) 252 WP_004231769.1 30S ribosomal protein S20 -
  EL084_RS03955 (NCTC10389_00834) - 798898..800076 (+) 1179 WP_126440223.1 ISL3 family transposase -
  EL084_RS03960 (NCTC10389_00835) ciaH 800114..801439 (-) 1326 WP_126440224.1 sensor histidine kinase Regulator
  EL084_RS03965 (NCTC10389_00836) ciaR 801429..802103 (-) 675 WP_004231785.1 response regulator transcription factor Regulator
  EL084_RS03970 (NCTC10389_00837) - 802256..804799 (-) 2544 WP_126440225.1 M1 family metallopeptidase -
  EL084_RS03975 (NCTC10389_00838) phoU 805008..805661 (-) 654 WP_126440226.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 50128.22 Da        Isoelectric Point: 8.9457

>NTDB_id=1120438 EL084_RS03960 WP_126440224.1 800114..801439(-) (ciaH) [Streptococcus equinus strain NCTC10389]
MLNNIKKKLSTGTFSHFFLFFAVFTGIFIIMTIIILQIIRYGLYSSVDTTLQNAANNASDYVTRTMERSDSIQSDNTINQ
SGKNKQSSNGGLSNVSVLLYDCNGKIVNALDAFIQFGSLTTSVNDDKIGEISEEKMTTIFGQTEKYHVLTVRVYSSDYPT
IQYATFLISVRQLDEANERYVTITITVMVIFWIISILASIYLANWTRKPILESYEKQKRFVENASHELRTPLAVLQNRLE
SLFRRPDATILDNSESIAASLDEVRNMRILTTNLLNLARRDDGLKVELEEIHPSTFNEIFENYQMIAHENNKKFTAHNLA
NRPIKSDKTLLKQLMTILFDNAIKYTGDDGVIEFTIKTTERQTILTIADNGPGVSDADKQKIFDRFYRVDKARTRQQGGF
GLGLSLAKQIVDALKGDIQVKDNKPKGIIFEVRFNRHNFGK

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=1120438 EL084_RS03960 WP_126440224.1 800114..801439(-) (ciaH) [Streptococcus equinus strain NCTC10389]
ATGCTGAATAATATAAAGAAAAAATTATCTACGGGGACTTTCTCACACTTTTTCCTTTTTTTTGCTGTGTTTACAGGGAT
TTTCATTATTATGACAATTATTATCCTGCAAATCATCCGATATGGTTTATATTCTTCTGTCGACACGACATTACAAAACG
CTGCTAATAATGCTAGTGATTATGTTACGAGAACGATGGAGAGAAGTGACTCGATTCAATCCGATAATACGATTAATCAA
TCTGGGAAAAATAAACAGAGTTCAAATGGTGGATTGAGTAATGTTAGTGTCCTTTTGTATGATTGCAACGGTAAAATAGT
TAATGCTTTGGATGCCTTTATTCAATTTGGCTCACTAACGACGAGCGTTAATGATGATAAAATCGGTGAAATAAGCGAAG
AGAAGATGACTACGATTTTCGGTCAAACTGAAAAGTATCACGTCTTGACTGTCAGAGTTTATAGCAGTGATTATCCAACA
ATTCAATACGCAACCTTTCTAATTAGTGTTCGTCAGCTTGACGAGGCAAATGAAAGATATGTGACAATTACTATTACAGT
TATGGTTATCTTTTGGATTATTTCAATTTTAGCGAGTATTTATCTTGCAAACTGGACTCGTAAACCGATTCTTGAAAGTT
ATGAAAAACAGAAACGCTTTGTTGAGAATGCCAGTCATGAGTTGAGAACGCCGCTTGCTGTTTTGCAAAATCGTCTTGAA
AGTTTGTTTAGACGTCCAGATGCAACAATTTTAGATAATAGCGAAAGTATTGCTGCAAGTCTTGATGAAGTGCGAAATAT
GCGTATTCTGACAACAAATCTTTTAAATCTTGCTAGACGTGATGATGGTTTGAAAGTTGAATTGGAAGAGATTCATCCAT
CAACCTTTAATGAGATTTTTGAAAATTATCAGATGATTGCTCACGAAAATAATAAAAAGTTCACTGCACACAATTTAGCT
AATCGTCCGATAAAATCAGATAAGACTCTTTTGAAACAACTAATGACTATTTTATTTGATAATGCCATTAAGTACACTGG
TGATGATGGCGTTATTGAATTTACCATTAAAACAACAGAACGCCAAACTATTTTAACTATTGCTGATAACGGACCTGGTG
TTAGTGATGCCGATAAACAGAAGATTTTTGATCGCTTTTACCGTGTCGACAAGGCAAGGACGCGCCAACAAGGGGGATTT
GGTTTGGGTTTGTCTCTAGCGAAGCAAATTGTTGATGCTTTGAAGGGTGATATTCAGGTTAAAGATAACAAACCAAAAGG
AATTATTTTTGAAGTTCGTTTCAACAGACATAATTTTGGTAAATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(327-434)

His Kinase A (phospho-acceptor) domain (HisKA)

(217-283)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

59.08

98.639

0.583
  ciaH Streptococcus pneumoniae Rx1

51.606

98.866

0.51
  ciaH Streptococcus pneumoniae D39

51.606

98.866

0.51
  ciaH Streptococcus pneumoniae R6

51.606

98.866

0.51
  ciaH Streptococcus pneumoniae TIGR4

51.606

98.866

0.51

Multiple sequence alignment