Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   EL084_RS01475 Genome accession   NZ_LR134292
Coordinates   288195..290093 (+) Length   632 a.a.
NCBI ID   WP_126439968.1    Uniprot ID   -
Organism   Streptococcus equinus strain NCTC10389     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 283195..295093
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL084_RS01460 (NCTC10389_00304) fmt 285173..286108 (+) 936 WP_115254920.1 methionyl-tRNA formyltransferase -
  EL084_RS01465 (NCTC10389_00305) rsmB 286098..287420 (+) 1323 WP_126439967.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  EL084_RS01470 (NCTC10389_00306) - 287458..288195 (+) 738 WP_044023444.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  EL084_RS01475 (NCTC10389_00307) pknB 288195..290093 (+) 1899 WP_126439968.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  EL084_RS01480 (NCTC10389_00308) liaF 290243..290938 (+) 696 WP_126439969.1 cell wall-active antibiotics response protein LiaF -
  EL084_RS01485 (NCTC10389_00309) - 290935..291960 (+) 1026 WP_003067329.1 sensor histidine kinase -
  EL084_RS01490 (NCTC10389_00310) - 291944..292588 (+) 645 WP_003067327.1 response regulator transcription factor -
  EL084_RS01495 (NCTC10389_00311) - 292712..294112 (+) 1401 WP_126439970.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  EL084_RS01500 (NCTC10389_00312) - 294112..294468 (+) 357 WP_003067323.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 632 a.a.        Molecular weight: 68786.68 Da        Isoelectric Point: 5.7168

>NTDB_id=1120427 EL084_RS01475 WP_126439968.1 288195..290093(+) (pknB) [Streptococcus equinus strain NCTC10389]
MIQIGKLFAGRYRILKSIGRGGMADVYLAKDLILDNEEVAIKVLRTNYQTDQIAVARFQREARAMAELNHPNIVSIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNNEVVRIMEEVLSAMTLAHQQGIVHRDLKPQNILLTKDGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIAENKNVP
QALENVVIKATAKRLSDRYASTFEMSRDLMTALSYNRSRERKLVFEDTENTKTLPKVTTSTPVPSTTEQLLKKQKAAKEN
KEVANQKAPKAKAKKKKSHRIFGTLMKIFFAVVVVAIAIFTYLTLSTPASVNVPDVSGAALSDAKTSLLSSGLKIGDIHK
VSSDTVAEGYVVKTDPTAGSSKKEGAKVDIYVSKGTSGFKIKDYTGQNYQDVIKELEKKHGISSKMIDIEWVTDTSYDSG
TIISQTPEEGTKVSNKDKITFEVAAITMPSLIGYTYQEAIAELNSMGVSSSHITIYMADATSSTGYSRVNSVSSSAVVVA
QDPYYGGAVEGEVNLYFSSETAAQPSEKTSQLAPELSETSETSETSESSESSSSSSGSSTEESSEAATEMQQ

Nucleotide


Download         Length: 1899 bp        

>NTDB_id=1120427 EL084_RS01475 WP_126439968.1 288195..290093(+) (pknB) [Streptococcus equinus strain NCTC10389]
ATGATTCAGATTGGCAAATTATTTGCTGGTCGTTATCGTATCCTTAAATCAATCGGACGGGGTGGAATGGCAGATGTTTA
TCTTGCCAAAGATCTGATTCTTGATAATGAAGAAGTAGCCATCAAAGTTCTTCGGACTAATTATCAAACAGATCAAATTG
CCGTAGCTCGTTTCCAACGTGAAGCGCGCGCCATGGCAGAGTTGAACCATCCCAATATTGTTTCGATTCGAGATATTGGA
GAAGAAGACGGACAGCAATTCTTAGTAATGGAATATGTTGATGGTTCTGACTTGAAAAAATACATTCAAGATCATGCGCC
TCTATCTAATAACGAAGTTGTTAGAATTATGGAAGAAGTCTTGTCAGCAATGACTCTTGCCCATCAACAAGGAATTGTTC
ACCGTGACTTAAAACCACAAAATATTTTGTTGACTAAAGACGGAACTGTAAAAGTTACTGACTTTGGTATTGCTGTAGCT
TTTGCAGAAACAAGTTTAACACAGACAAACTCAATGCTTGGTAGTGTGCATTATTTGTCACCTGAACAAGCGCGAGGTTC
AAAAGCCACTGTTCAAAGTGATATCTATGCTATGGGGATTATGTTGTTTGAAATGTTAACAGGTCACATTCCTTATGATG
GCGACTCAGCGGTGACAATTGCACTGCAACATTTTCAAAAACCTCTACCATCCATTATCGCTGAAAATAAGAATGTTCCA
CAGGCTTTAGAAAATGTAGTTATCAAAGCAACAGCAAAACGTTTAAGCGACCGTTATGCATCAACTTTTGAAATGAGTCG
TGATTTGATGACGGCACTTTCATACAACCGTAGTCGAGAACGTAAACTTGTTTTTGAGGATACAGAAAATACTAAGACAC
TTCCAAAAGTGACTACTTCAACACCTGTTCCATCAACGACAGAACAATTGTTGAAAAAACAAAAAGCTGCAAAAGAAAAT
AAAGAAGTAGCAAATCAAAAAGCACCTAAAGCAAAGGCTAAAAAGAAAAAATCTCATCGTATATTTGGTACTTTGATGAA
AATCTTCTTTGCAGTTGTTGTTGTTGCGATTGCTATCTTTACTTACTTAACTTTAAGTACACCAGCTTCAGTTAATGTTC
CAGACGTGTCTGGTGCGGCTTTATCTGATGCTAAGACAAGCTTGTTATCATCTGGTTTGAAGATTGGTGATATCCACAAA
GTTTCTAGTGATACAGTTGCTGAAGGTTACGTTGTTAAAACAGATCCGACTGCTGGTTCATCTAAGAAAGAAGGAGCTAA
AGTTGATATTTATGTATCAAAAGGAACTTCAGGCTTCAAGATAAAAGACTACACTGGTCAAAATTATCAAGATGTCATCA
AGGAGCTTGAAAAGAAACATGGTATTTCAAGTAAAATGATTGATATCGAGTGGGTAACTGATACTTCATATGATAGTGGT
ACTATTATCAGCCAAACTCCAGAAGAAGGAACAAAAGTTAGTAACAAAGATAAAATCACTTTTGAGGTAGCAGCAATCAC
AATGCCTAGTCTTATTGGTTATACTTACCAAGAAGCGATTGCTGAGTTAAATTCTATGGGTGTATCAAGCTCACATATTA
CAATTTATATGGCAGATGCAACTTCATCAACAGGATATTCTCGAGTAAACTCAGTATCAAGTTCTGCGGTCGTCGTTGCT
CAGGATCCTTATTATGGTGGGGCTGTTGAAGGAGAGGTTAACCTTTACTTCTCTTCAGAAACGGCTGCGCAACCATCTGA
AAAAACGTCACAATTAGCTCCAGAATTATCTGAAACAAGTGAGACAAGTGAGACAAGTGAATCAAGTGAATCAAGTTCAT
CAAGTAGTGGTAGTAGTACTGAAGAAAGTTCAGAAGCAGCTACTGAAATGCAACAATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(440-503)

PASTA domain (PASTA)

(506-578)

PASTA domain (PASTA)

(371-434)

Protein kinase domain (Pkinase)

(12-249)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

66.9

90.348

0.604
  stkP/pknB Streptococcus salivarius strain HSISS4

64.177

93.196

0.598
  stkP Streptococcus pneumoniae TIGR4

58.379

85.918

0.502
  stkP Streptococcus pneumoniae D39

58.195

85.918

0.5
  stkP Streptococcus pneumoniae R6

58.195

85.918

0.5
  stkP Streptococcus pneumoniae Rx1

58.011

85.918

0.498

Multiple sequence alignment