Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   EL084_RS00890 Genome accession   NZ_LR134292
Coordinates   167019..167780 (+) Length   253 a.a.
NCBI ID   WP_126439920.1    Uniprot ID   -
Organism   Streptococcus equinus strain NCTC10389     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 162019..172780
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL084_RS00875 (NCTC10389_00184) - 162425..163996 (-) 1572 WP_126439917.1 ABC transporter permease subunit -
  EL084_RS00880 (NCTC10389_00185) - 164133..166025 (+) 1893 WP_126439918.1 DUF2207 domain-containing protein -
  EL084_RS00885 (NCTC10389_00186) - 166077..166916 (+) 840 WP_126439919.1 undecaprenyl-diphosphate phosphatase -
  EL084_RS00890 (NCTC10389_00187) mecA 167019..167780 (+) 762 WP_126439920.1 adaptor protein MecA Regulator
  EL084_RS00895 (NCTC10389_00188) - 167782..168945 (+) 1164 WP_126439921.1 glycosyltransferase family 4 protein -
  EL084_RS00900 (NCTC10389_00189) sufC 169067..169837 (+) 771 WP_003067585.1 Fe-S cluster assembly ATPase SufC -
  EL084_RS00905 (NCTC10389_00190) sufD 169915..171177 (+) 1263 WP_003067583.1 Fe-S cluster assembly protein SufD -
  EL084_RS00910 (NCTC10389_00191) - 171179..172411 (+) 1233 WP_003067581.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29141.95 Da        Isoelectric Point: 4.0260

>NTDB_id=1120421 EL084_RS00890 WP_126439920.1 167019..167780(+) (mecA) [Streptococcus equinus strain NCTC10389]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEI
NKDINFEDLAAFDDVSNMSPEEFFKTLEQTMMAKDDTEAHEKLGKIEEMMEGAVEEVLTEHAKQADTEPEEDVNPSDYVH
YVLDFPSLEATVAFSKAIDFPVEASELYKMDGVYYMTILLDLQNQPSYYANLMYARMLEYAGAGTKTRAYLQEHAVELLT
DDAVAKLKMIELV

Nucleotide


Download         Length: 762 bp        

>NTDB_id=1120421 EL084_RS00890 WP_126439920.1 167019..167780(+) (mecA) [Streptococcus equinus strain NCTC10389]
ATGGAAATGAAACAGATTAGCGAGACAACGCTAAAAATAACGATTAGTATGGAAGATTTAGAAGAACGAGGAATGGAGTT
AAAAGACTTTTTGATTCCGCAAGAAAAAACAGAAGAGTTCTTCTATTCAGTAATGGATGAGTTAGATTTACCAGATAATT
TTAAAGATAGCGGCATGCTTAGTTTTCGTGTGACACCACGTAAAGACCGTCTTGATGTATTTGTCACAAAATCAGAAATT
AACAAAGATATCAATTTTGAAGATTTAGCTGCATTTGATGATGTGTCTAACATGTCACCAGAAGAATTCTTTAAAACGTT
AGAACAAACAATGATGGCTAAAGATGACACTGAAGCTCATGAAAAATTAGGTAAAATCGAAGAAATGATGGAAGGTGCTG
TTGAAGAAGTCTTGACAGAGCACGCTAAGCAAGCAGATACAGAACCTGAAGAAGATGTAAATCCATCTGATTATGTTCAT
TACGTCTTAGATTTTCCAAGTTTAGAAGCAACGGTTGCTTTTTCTAAAGCGATTGATTTTCCTGTAGAAGCTTCTGAACT
TTACAAGATGGACGGCGTTTATTACATGACAATTTTGCTTGATTTGCAGAACCAACCTTCTTATTATGCAAATTTGATGT
ATGCCCGTATGTTAGAATACGCTGGCGCTGGTACAAAAACTCGTGCTTACTTGCAAGAGCACGCAGTTGAACTATTGACG
GATGATGCCGTTGCAAAATTAAAAATGATTGAGTTAGTATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

65.6

98.814

0.648
  mecA Streptococcus thermophilus LMD-9

60.643

98.419

0.597
  mecA Streptococcus thermophilus LMG 18311

59.839

98.419

0.589
  mecA Streptococcus pneumoniae Rx1

49.412

100

0.498
  mecA Streptococcus pneumoniae D39

49.412

100

0.498
  mecA Streptococcus pneumoniae R6

49.412

100

0.498
  mecA Streptococcus pneumoniae TIGR4

49.412

100

0.498

Multiple sequence alignment