Detailed information NTG1120252

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: EL087_RS02660
• Genome accession: NZ_LR134288
• Coordinates: 531610..532635 (+)
• Length: 341 a.a.
• NCBI ID: WP_126406705.1
• Uniprot ID: A0A4U9YJ01
• Organism: Streptococcus milleri strain NCTC11169
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 526610..537635

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL087_RS02635 (NCTC11169_00530)	-	526912..527226 (+)	315	WP_003040185.1	PTS cellobiose transporter subunit IIB	-
EL087_RS02640 (NCTC11169_00531)	-	527287..529278 (+)	1992	WP_126406697.1	BglG family transcription antiterminator	-
EL087_RS02645 (NCTC11169_00532)	-	529291..529608 (+)	318	WP_126406699.1	PTS cellobiose transporter subunit IIA	-
EL087_RS02650 (NCTC11169_00533)	-	529632..530138 (+)	507	WP_070671153.1	hypothetical protein	-
EL087_RS02655 (NCTC11169_00534)	celB	530178..531521 (+)	1344	WP_126406703.1	PTS cellobiose transporter subunit IIC	-
EL087_RS02660 (NCTC11169_00535)	coiA	531610..532635 (+)	1026	WP_126406705.1	competence protein CoiA	Machinery gene
EL087_RS02665 (NCTC11169_00536)	pepF	532587..534389 (+)	1803	WP_003040270.1	oligoendopeptidase F	Regulator
EL087_RS02670 (NCTC11169_00537)	-	534391..535074 (+)	684	WP_003040265.1	O-methyltransferase	-
EL087_RS02675 (NCTC11169_00538)	prsA	535181..536119 (+)	939	WP_059220537.1	peptidylprolyl isomerase PrsA	-
EL087_RS02680	-	536258..536827 (+)	570	WP_164558124.1	LURP-one-related/scramblase family protein	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 40518.77 Da
• Isoelectric Point: 9.4472

>NTDB_id=1120252 EL087_RS02660 WP_126406705.1 531610..532635(+) (coiA) [Streptococcus milleri strain NCTC11169]
MLMACQENGKMLNAVEDRVNPLDRFFCPACQEAVRFKNGKVMRPHFAHISLKNCHFSTENESAEHLNLKAALFTWARKSS
HAIQVEAYLPELQQIADLLVEKQIALEVQCSSLSPKRLKERTDSYRQYGYRVLWLLGKKLWLKNALTNLQKDFLYFSQNM
GFHLWELDEQKQLLRLKYLIHEDLHGKAQYKEKIFTFGKGNLLDIFRQPFCKQEMTSFLAKEDKNICRYVRQQLYYQQPK
WMKWQAELYQAGDNLLTKTANDFYPQVQPVRSSSFCQIFQDLTPYYQQFSAYYEKNKNLQILYPPAFYAKIFGNIYDRIG
RTEEILWQNKEMKLKKNTLGT

Nucleotide

• Length: 1026 bp

>NTDB_id=1120252 EL087_RS02660 WP_126406705.1 531610..532635(+) (coiA) [Streptococcus milleri strain NCTC11169]
ATGTTAATGGCTTGTCAGGAAAACGGAAAAATGCTAAATGCTGTGGAAGATAGGGTAAATCCGCTGGATAGATTTTTCTG
TCCGGCTTGTCAGGAAGCAGTGCGATTTAAGAATGGCAAGGTGATGCGACCGCATTTTGCTCATATTTCCTTGAAAAACT
GCCATTTTTCTACGGAAAATGAAAGTGCAGAACACCTAAATCTGAAAGCTGCTTTGTTTACTTGGGCTAGAAAGTCTAGT
CATGCGATTCAAGTAGAAGCTTATTTACCAGAATTGCAGCAAATTGCAGATTTGTTAGTTGAAAAACAAATTGCACTTGA
AGTTCAATGCAGTTCGCTTAGTCCAAAGCGCTTAAAAGAGCGTACAGACAGTTATCGTCAGTATGGCTATCGCGTTCTTT
GGCTCTTGGGAAAGAAACTTTGGCTGAAAAATGCCTTGACCAATTTGCAAAAGGATTTTCTCTATTTTAGTCAAAATATG
GGCTTTCATCTGTGGGAATTGGACGAACAAAAACAGCTTTTGAGGCTTAAATACTTGATTCATGAAGATTTGCATGGCAA
GGCGCAGTATAAGGAAAAAATTTTTACTTTTGGCAAAGGAAATCTTTTAGACATCTTTCGTCAGCCATTCTGCAAGCAGG
AGATGACGAGTTTTCTGGCAAAAGAAGATAAAAATATTTGCCGTTATGTGCGTCAGCAGCTCTACTATCAGCAGCCCAAA
TGGATGAAATGGCAAGCAGAATTGTACCAAGCGGGTGATAATTTATTAACCAAAACAGCTAATGACTTTTATCCGCAGGT
TCAACCTGTTCGTTCCAGCTCTTTCTGCCAGATTTTTCAAGATCTCACACCTTATTACCAGCAATTTTCAGCTTATTATG
AAAAAAATAAAAATCTCCAAATTCTCTATCCCCCAGCTTTTTATGCAAAGATTTTTGGCAATATTTATGATAGAATAGGA
AGGACGGAGGAAATTTTATGGCAAAACAAAGAAATGAAATTGAAGAAAAATACACTTGGGACCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (1-249)

3D structure

• AlphaFold DB: A0A4U9YJ01

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus mitis NCTC 12261	54.14	92.082	0.499
coiA	Streptococcus pneumoniae Rx1	53.503	92.082	0.493
coiA	Streptococcus pneumoniae D39	53.503	92.082	0.493
coiA	Streptococcus pneumoniae R6	53.503	92.082	0.493
coiA	Streptococcus pneumoniae TIGR4	53.185	92.082	0.49
coiA	Lactococcus lactis subsp. cremoris KW2	44.72	94.428	0.422