Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   EL087_RS01845 Genome accession   NZ_LR134288
Coordinates   365594..367468 (+) Length   624 a.a.
NCBI ID   WP_126406508.1    Uniprot ID   -
Organism   Streptococcus milleri strain NCTC11169     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 360594..372468
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL087_RS01830 (NCTC11169_00366) fmt 362600..363535 (+) 936 WP_126406499.1 methionyl-tRNA formyltransferase -
  EL087_RS01835 (NCTC11169_00367) rsmB 363525..364838 (+) 1314 WP_126406502.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  EL087_RS01840 (NCTC11169_00368) - 364857..365597 (+) 741 WP_126406505.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  EL087_RS01845 (NCTC11169_00369) stkP 365594..367468 (+) 1875 WP_126406508.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  EL087_RS01850 (NCTC11169_00370) liaF 367729..368427 (+) 699 WP_003025810.1 cell wall-active antibiotics response protein LiaF -
  EL087_RS01855 (NCTC11169_00371) - 368424..369419 (+) 996 WP_059221090.1 sensor histidine kinase -
  EL087_RS01860 (NCTC11169_00372) - 369421..370053 (+) 633 WP_003028406.1 response regulator transcription factor -
  EL087_RS01865 (NCTC11169_00373) - 370093..371493 (+) 1401 WP_126406510.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  EL087_RS01870 (NCTC11169_00374) - 371495..371866 (+) 372 WP_126406513.1 S1 RNA-binding domain-containing protein -
  EL087_RS01875 (NCTC11169_00375) - 371995..372312 (-) 318 WP_049516901.1 DUF960 domain-containing protein -

Sequence

Protein


Download         Length: 624 a.a.        Molecular weight: 67547.58 Da        Isoelectric Point: 9.3344

>NTDB_id=1120245 EL087_RS01845 WP_126406508.1 365594..367468(+) (stkP) [Streptococcus milleri strain NCTC11169]
MIQVGKIFAGRYKIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKEHAPLSNEEAVRIMGQILLAMRLAHTHGIVHRDLKPQNVLLTPDGDAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPNVP
QALENVVIKATAKKLTDRYQSVAEMYVDLSSCLSADRRNEKKLVFDDTAKADTKTLPKVSQNTLTSATKSTPAPTKEVVS
STPTPTPKAKKKRRLRTRYKVLLSAVVLVIVALVALVYLSPSNVKIPDVTGKTIAQARSAIETAGLKVGKEKDEYSDSVK
KDSVIRTNPEAGTQRREGSTVDLIVSKGTKTFIMEDYKGQKRADAINNLVQKYKVSKGLIKTEEVESSEYAAGTVVDQTP
AAGSTYDLTSKTRITLKVAKSVSSVTMPSYIGSTYEFAYNNLTEVIGIQGANIEKRTVTTAPAGTQANTIIRQTPEAGQS
LNLKSDRIVLYVYEPKTEDSSTSGSSSQSDSSSDKTSPSSSSSSASGNDGSSSKTPDTSASASN

Nucleotide


Download         Length: 1875 bp        

>NTDB_id=1120245 EL087_RS01845 WP_126406508.1 365594..367468(+) (stkP) [Streptococcus milleri strain NCTC11169]
ATGATTCAAGTCGGCAAGATATTTGCCGGACGATATAAAATCATCAAACAAATTGGTCGAGGTGGCATGGCAGATGTCTA
CTTGGCGAAAGACTTGATTTTAGACGGGGAAGAAGTCGCAGTTAAGGTTCTAAGAACCAATTACCAGACAGATCCGATTG
CTGTGGCGCGTTTTCAAAGAGAGGCGCGAGCTATGGCAGACTTGGATCATCCTCATATTGTTCGGATTACCGACATTGGA
GAAGAAGAAGGTCAGCAATATCTAGCAATGGAATATGTGGCTGGACTCGACTTAAAGCGCTATATCAAAGAGCATGCTCC
TTTGTCCAATGAAGAAGCGGTTCGAATCATGGGACAAATCCTTTTGGCGATGCGTTTGGCACACACGCACGGGATTGTTC
ACCGTGATTTGAAACCTCAAAATGTCCTTTTAACTCCAGATGGCGATGCAAAAGTCACTGACTTTGGAATTGCGGTAGCT
TTTGCAGAAACGAGCTTAACGCAAACCAACTCTATGCTGGGGTCTGTACATTATTTGTCACCAGAACAGGCGCGTGGTTC
AAAAGCGACCGTTCAGAGCGATATTTATGCCATGGGGATTATTTTCTATGAAATGCTGACAGGACATATCCCTTATGATG
GAGATAGTGCTGTTACGATTGCCCTACAGCATTTCCAAAAGCCTCTTCCTTCTGTGATTGCTGAAAATCCAAACGTTCCA
CAAGCATTGGAAAATGTAGTCATCAAGGCAACGGCAAAAAAATTGACGGATCGTTATCAGTCAGTTGCAGAAATGTATGT
GGATTTATCAAGCTGCTTATCTGCTGACCGTCGAAATGAGAAAAAACTAGTTTTTGATGACACTGCTAAAGCAGACACAA
AGACACTGCCGAAAGTATCACAAAATACCTTGACTTCTGCGACGAAGTCAACACCTGCTCCTACAAAAGAAGTAGTCAGT
AGTACGCCTACGCCTACGCCAAAAGCAAAAAAGAAGCGCCGTTTAAGAACGCGCTATAAAGTTTTGTTATCAGCGGTGGT
TTTAGTCATCGTAGCTCTGGTGGCTTTAGTCTATTTGAGTCCGTCAAATGTAAAAATCCCAGATGTTACTGGAAAAACTA
TTGCCCAAGCACGTTCTGCAATCGAAACTGCAGGTTTGAAAGTTGGCAAGGAAAAAGACGAATACAGTGATTCTGTTAAA
AAAGATTCAGTTATTCGCACCAATCCAGAAGCGGGAACGCAACGTCGTGAGGGCAGTACGGTGGATCTGATTGTCTCAAA
AGGGACTAAAACTTTTATTATGGAAGATTATAAAGGTCAGAAAAGAGCAGATGCTATCAACAATCTGGTACAAAAATACA
AGGTTTCAAAAGGCTTAATTAAAACAGAAGAAGTTGAAAGTAGTGAGTATGCGGCAGGAACAGTTGTTGATCAAACACCA
GCAGCAGGCAGCACTTATGATTTGACTTCAAAGACACGTATTACGTTAAAAGTAGCGAAGTCCGTTTCAAGTGTCACGAT
GCCAAGCTATATCGGCTCAACTTATGAATTTGCTTATAATAATTTGACAGAAGTGATTGGTATTCAAGGTGCGAATATTG
AAAAACGTACGGTTACAACAGCTCCAGCGGGTACACAGGCAAATACGATTATCAGACAAACCCCAGAAGCTGGTCAGTCT
TTGAATTTGAAGAGTGATCGCATTGTCTTATATGTATATGAGCCAAAAACCGAAGATTCTTCAACATCTGGAAGTAGTTC
ACAATCTGATAGCAGCTCAGATAAAACTAGCCCATCCTCTAGCAGTTCGTCAGCTAGTGGTAATGATGGAAGCAGCTCAA
AAACACCAGACACAAGTGCTAGTGCAAGTAATTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(505-573)

PASTA domain (PASTA)

(364-427)

PASTA domain (PASTA)

(433-500)

Protein kinase domain (Pkinase)

(12-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

65.983

93.75

0.619
  stkP Streptococcus pneumoniae D39

65.641

93.75

0.615
  stkP Streptococcus pneumoniae R6

65.641

93.75

0.615
  stkP Streptococcus pneumoniae Rx1

65.47

93.75

0.614
  pknB Streptococcus mutans UA159

58.632

93.75

0.55
  stkP/pknB Streptococcus salivarius strain HSISS4

55.333

96.154

0.532

Multiple sequence alignment