Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   EL087_RS01680 Genome accession   NZ_LR134288
Coordinates   329419..330174 (+) Length   251 a.a.
NCBI ID   WP_003028444.1    Uniprot ID   A0AAI9J7E8
Organism   Streptococcus milleri strain NCTC11169     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 324419..335174
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL087_RS01665 (NCTC11169_00333) - 324804..326369 (-) 1566 WP_126406438.1 ABC transporter substrate-binding protein/permease -
  EL087_RS01670 (NCTC11169_00334) - 326497..328386 (+) 1890 WP_126406441.1 DUF2207 domain-containing protein -
  EL087_RS01675 (NCTC11169_00335) - 328453..329295 (+) 843 WP_126406444.1 undecaprenyl-diphosphate phosphatase -
  EL087_RS01680 (NCTC11169_00336) mecA 329419..330174 (+) 756 WP_003028444.1 adaptor protein MecA Regulator
  EL087_RS01685 (NCTC11169_00337) - 330165..331331 (+) 1167 WP_003028442.1 glycosyltransferase family 4 protein -
  EL087_RS01690 (NCTC11169_00338) sufC 331423..332193 (+) 771 WP_003025885.1 Fe-S cluster assembly ATPase SufC -
  EL087_RS01695 (NCTC11169_00339) sufD 332233..333495 (+) 1263 WP_003025884.1 Fe-S cluster assembly protein SufD -
  EL087_RS01700 (NCTC11169_00340) - 333511..334743 (+) 1233 WP_126406446.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 29061.88 Da        Isoelectric Point: 4.1324

>NTDB_id=1120243 EL087_RS01680 WP_003028444.1 329419..330174(+) (mecA) [Streptococcus milleri strain NCTC11169]
MEMKQISDTTIKITIKLEDLEERGMEMADFLVPQEKTEEFFYAILDELEMPESFLDSGMLSFRVTPKPDRLDVFVTKSKI
DKNLNFDDLADLPDVEELSQMSPDEFLKTLEKNIFEKSKDDMEAVRSLETAEADDNTSTSDMEEQEENSDELTQKYIYYI
LKFSSLKEAIVFSKTVDYAVNTSELYKMDGYYYLTILVDIEGHPKRYPAWLLASMREHAEDTDVTRAVLQEHGYLLLVNE
AVASLKKVKCL

Nucleotide


Download         Length: 756 bp        

>NTDB_id=1120243 EL087_RS01680 WP_003028444.1 329419..330174(+) (mecA) [Streptococcus milleri strain NCTC11169]
ATGGAAATGAAGCAAATTAGTGATACAACGATTAAGATCACAATAAAATTAGAAGATTTAGAAGAACGTGGAATGGAGAT
GGCAGATTTTCTTGTTCCGCAAGAAAAGACAGAAGAGTTTTTCTATGCAATTTTAGATGAGTTGGAAATGCCAGAGAGTT
TTTTGGATAGCGGTATGCTCAGTTTTCGTGTAACTCCTAAACCAGACCGACTGGATGTGTTTGTCACCAAGTCTAAGATT
GATAAGAATCTGAATTTTGATGATTTGGCAGATTTACCAGATGTAGAAGAGCTGTCTCAAATGTCTCCTGATGAATTTCT
AAAGACATTAGAAAAAAATATTTTTGAGAAAAGTAAAGACGATATGGAGGCTGTTCGTTCTTTGGAAACGGCGGAAGCAG
ACGATAACACAAGCACTTCTGATATGGAAGAACAAGAGGAAAATAGTGACGAGCTAACGCAAAAATATATCTATTACATT
TTGAAATTTTCCAGCCTGAAAGAAGCGATTGTCTTTTCTAAAACAGTAGACTATGCTGTTAACACTTCGGAGTTGTACAA
AATGGATGGTTACTATTATTTAACAATCTTGGTTGATATTGAAGGACATCCTAAGCGTTATCCAGCTTGGCTTCTGGCTT
CTATGCGTGAACATGCAGAAGACACAGATGTGACAAGAGCTGTTTTACAAGAGCATGGTTATTTATTGCTTGTCAACGAG
GCAGTTGCCAGTCTTAAAAAGGTTAAATGCTTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

66.129

98.805

0.653
  mecA Streptococcus pneumoniae D39

66.129

98.805

0.653
  mecA Streptococcus pneumoniae R6

66.129

98.805

0.653
  mecA Streptococcus pneumoniae TIGR4

65.726

98.805

0.649
  mecA Streptococcus mutans UA159

49.597

98.805

0.49
  mecA Streptococcus thermophilus LMD-9

45.882

100

0.466
  mecA Streptococcus thermophilus LMG 18311

45.49

100

0.462

Multiple sequence alignment