Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   EL100_RS06480 Genome accession   NZ_LR134285
Coordinates   1341588..1342289 (+) Length   233 a.a.
NCBI ID   WP_048717457.1    Uniprot ID   A0A3R9MQW7
Organism   Streptococcus australis strain NCTC3168     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1336588..1347289
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL100_RS06470 (NCTC3168_01328) thrS 1337655..1339598 (+) 1944 WP_126404597.1 threonine--tRNA ligase -
  EL100_RS06475 (NCTC3168_01329) - 1339959..1341008 (-) 1050 WP_126404595.1 DUF389 domain-containing protein -
  EL100_RS06480 (NCTC3168_01330) micA 1341588..1342289 (+) 702 WP_048717457.1 response regulator YycF Regulator
  EL100_RS06485 (NCTC3168_01331) micB 1342282..1343628 (+) 1347 WP_126404593.1 cell wall metabolism sensor histidine kinase VicK Regulator
  EL100_RS06490 (NCTC3168_01332) vicX 1343637..1344446 (+) 810 WP_125374345.1 MBL fold metallo-hydrolase Regulator
  EL100_RS06495 (NCTC3168_01333) - 1344659..1345048 (+) 390 WP_414386485.1 YbaN family protein -
  EL100_RS06500 (NCTC3168_01334) rnc 1345207..1345908 (+) 702 WP_126405060.1 ribonuclease III -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26615.54 Da        Isoelectric Point: 4.7260

>NTDB_id=1120182 EL100_RS06480 WP_048717457.1 1341588..1342289(+) (micA) [Streptococcus australis strain NCTC3168]
MKKILVVDDEKPISDIIKFNMAKEGYEVLTAFDGKEALAVFEAESPDILILDLMLPEIDGLEVARTIRKTSNVPIIVLSA
KDTEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRTELTVESQTESTSDSDIVIGDLKIIPDAFLAQKKGKELELTH
REFELLYHLATHVGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDIPGRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=1120182 EL100_RS06480 WP_048717457.1 1341588..1342289(+) (micA) [Streptococcus australis strain NCTC3168]
ATGAAGAAAATTCTTGTTGTAGATGATGAAAAGCCGATTTCGGATATTATAAAATTCAATATGGCCAAAGAAGGCTATGA
AGTCTTGACTGCCTTCGATGGAAAAGAAGCACTGGCTGTTTTTGAAGCTGAGAGCCCAGATATTTTGATCTTGGACCTCA
TGCTTCCTGAAATTGATGGTTTGGAAGTAGCACGTACCATTCGAAAGACCAGTAATGTGCCGATTATTGTCTTATCTGCA
AAAGATACAGAATTTGATAAGGTCATCGGTCTTGAAATTGGTGCGGATGACTATGTGACTAAGCCATTCTCAAATCGTGA
GCTTCAAGCTCGCGTAAAAGCTTTATTGCGTCGGACAGAACTAACGGTAGAATCACAGACAGAGTCTACATCAGATTCAG
ATATTGTGATTGGTGATTTGAAAATCATTCCGGATGCCTTCCTTGCTCAGAAAAAAGGCAAAGAGCTCGAGTTGACCCAT
CGCGAATTTGAGCTGCTCTATCACTTGGCAACCCATGTAGGCCAAGTCATGACCCGTGAGCATTTGCTGGAAACAGTCTG
GGGCTACGATTATTTTGGAGATGTTCGGACAGTGGACGTAACGATTCGACGTTTGCGTGAAAAAATCGAAGATATTCCAG
GCCGTCCGGAGTATATTTTAACGCGCCGCGGTGTCGGTTACTATATGAGAAACAATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3R9MQW7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

80.687

100

0.807
  vicR Streptococcus mutans UA159

77.542

100

0.785
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.022

99.142

0.446
  covR Streptococcus salivarius strain HSISS4

41.048

98.283

0.403

Multiple sequence alignment