Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   EL100_RS01710 Genome accession   NZ_LR134285
Coordinates   337045..337791 (-) Length   248 a.a.
NCBI ID   WP_126403794.1    Uniprot ID   -
Organism   Streptococcus australis strain NCTC3168     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 332045..342791
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL100_RS01685 (NCTC3168_00347) sufU 332080..332514 (-) 435 WP_126403799.1 Fe-S cluster assembly sulfur transfer protein SufU -
  EL100_RS01690 (NCTC3168_00348) - 332501..333727 (-) 1227 WP_126403798.1 cysteine desulfurase -
  EL100_RS01695 (NCTC3168_00349) sufD 333730..334992 (-) 1263 WP_126403797.1 Fe-S cluster assembly protein SufD -
  EL100_RS01700 (NCTC3168_00350) sufC 335034..335804 (-) 771 WP_126403796.1 Fe-S cluster assembly ATPase SufC -
  EL100_RS01705 (NCTC3168_00351) - 335891..337048 (-) 1158 WP_126403795.1 glycosyltransferase family 4 protein -
  EL100_RS01710 (NCTC3168_00352) mecA 337045..337791 (-) 747 WP_126403794.1 adaptor protein MecA Regulator
  EL100_RS01715 (NCTC3168_00353) - 337959..338795 (-) 837 WP_126403793.1 undecaprenyl-diphosphate phosphatase -
  EL100_RS01720 (NCTC3168_00354) - 338955..340862 (-) 1908 WP_126403792.1 DUF2207 domain-containing protein -
  EL100_RS01725 (NCTC3168_00355) - 340982..342544 (+) 1563 WP_126403791.1 ABC transporter substrate-binding protein/permease -

Sequence

Protein


Download         Length: 248 a.a.        Molecular weight: 28836.50 Da        Isoelectric Point: 4.0837

>NTDB_id=1120152 EL100_RS01710 WP_126403794.1 337045..337791(-) (mecA) [Streptococcus australis strain NCTC3168]
MKMKQISDSTIKITIQLEDLEERGMEMADFLVPQEKTEEFFYTILDELEMPESFLDSGMLSFRVTPKPDKLDVFVTKSKI
DQHLNFDDFSDLPDMEELSQMSPDEFIKTLEKTISEKSKGDGDAIRHLEAEELADENQLSEEDTPNHPLDTRYIYYILQF
SQLEEVIRFTKTVHYAVETSELYKMDGIYYLTILIDLEGCPQDYPGWLLATMREYAEDTDTTRAVLQEHGHLLLVSDAIH
ELQKVNLV

Nucleotide


Download         Length: 747 bp        

>NTDB_id=1120152 EL100_RS01710 WP_126403794.1 337045..337791(-) (mecA) [Streptococcus australis strain NCTC3168]
ATGAAGATGAAGCAAATCAGTGATTCAACCATTAAAATCACGATTCAATTAGAGGATTTAGAAGAACGGGGCATGGAAAT
GGCCGATTTTTTGGTGCCTCAAGAAAAAACAGAAGAATTTTTCTATACCATCTTAGATGAATTGGAAATGCCAGAAAGCT
TCTTAGACAGTGGCATGTTGAGTTTCCGAGTGACTCCTAAGCCAGATAAGCTCGATGTTTTTGTGACCAAATCAAAAATT
GATCAACATCTAAATTTTGACGATTTTTCCGACTTGCCTGATATGGAAGAATTGTCGCAAATGTCTCCGGACGAATTTAT
CAAGACCTTGGAAAAAACCATTTCTGAAAAAAGTAAGGGAGACGGTGATGCTATCCGTCATTTAGAAGCTGAGGAATTGG
CTGATGAAAATCAGCTTTCAGAAGAAGATACACCGAATCATCCACTAGATACACGGTATATTTATTATATCCTCCAGTTT
TCTCAGTTAGAAGAAGTGATTCGGTTTACAAAAACAGTTCATTATGCTGTCGAGACTTCGGAACTTTATAAAATGGACGG
GATTTACTATTTAACCATCCTGATCGATTTGGAAGGGTGTCCGCAAGATTATCCAGGTTGGCTCTTGGCGACCATGCGTG
AATATGCGGAAGATACAGATACTACTAGAGCTGTCCTCCAGGAACATGGTCATCTCTTGCTCGTCTCAGATGCTATTCAC
GAACTTCAAAAGGTTAATTTGGTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

65.854

99.194

0.653
  mecA Streptococcus pneumoniae D39

65.854

99.194

0.653
  mecA Streptococcus pneumoniae R6

65.854

99.194

0.653
  mecA Streptococcus pneumoniae TIGR4

65.854

99.194

0.653
  mecA Streptococcus mutans UA159

50.4

100

0.508
  mecA Streptococcus thermophilus LMD-9

46.185

100

0.464
  mecA Streptococcus thermophilus LMG 18311

45.783

100

0.46

Multiple sequence alignment