Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   EL079_RS05430 Genome accession   NZ_LR134283
Coordinates   1115107..1116981 (-) Length   624 a.a.
NCBI ID   WP_018543640.1    Uniprot ID   -
Organism   Streptococcus anginosus strain NCTC10713     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1110107..1121981
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL079_RS05400 (NCTC10713_01127) - 1110263..1110580 (+) 318 WP_003031462.1 DUF960 domain-containing protein -
  EL079_RS05405 (NCTC10713_01128) - 1110706..1111080 (-) 375 WP_018543641.1 S1 RNA-binding domain-containing protein -
  EL079_RS05410 (NCTC10713_01129) - 1111082..1112482 (-) 1401 WP_003031456.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  EL079_RS05415 (NCTC10713_01130) - 1112522..1113154 (-) 633 WP_003031463.1 response regulator transcription factor -
  EL079_RS05420 (NCTC10713_01131) - 1113156..1114151 (-) 996 WP_003031470.1 sensor histidine kinase -
  EL079_RS05425 (NCTC10713_01132) liaF 1114148..1114846 (-) 699 WP_003025810.1 cell wall-active antibiotics response protein LiaF -
  EL079_RS05430 (NCTC10713_01133) stkP 1115107..1116981 (-) 1875 WP_018543640.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  EL079_RS05435 (NCTC10713_01134) - 1116978..1117718 (-) 741 WP_003031460.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  EL079_RS05440 (NCTC10713_01135) rsmB 1117737..1119050 (-) 1314 WP_003031466.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  EL079_RS05445 (NCTC10713_01136) fmt 1119040..1119975 (-) 936 WP_003031468.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 624 a.a.        Molecular weight: 67647.70 Da        Isoelectric Point: 9.4135

>NTDB_id=1120034 EL079_RS05430 WP_018543640.1 1115107..1116981(-) (stkP) [Streptococcus anginosus strain NCTC10713]
MIQVGKIFAGRYKIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKEHAPLSNEEAVRIMGQILLAMRLAHTHGIVHRDLKPQNVLLTPDGDAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPNVP
QALENVVIKATAKKLTDRYQSVAEMYVDLSSCLSADRRNEKKLVFDDTAKADTKTLPKVSQNTLTSATKSTPTPTKEAVS
SKPTPKPKAKKKRRLRTRYKVLLSAVVLVIAALVALVYLSPSNVKIPDVTGKTIAQARSAIETAGLKVGKEKDEYSDSVK
KDSVIRTNPEAGTQRREGSTVDLIVSKGTKTFIMEDYKGQKRADAINNLVQKYKVSKGLIKTEEVESSEYAAGTVVDQTP
AAGSTYDLTSKTRITLKVAKSVSSVTMPSYIGSTYEFAYNNLTEVIGIQGANIEKRTVTTAPAGTQANTIIRQTPEAGQS
LNLKSDRIVLYVYEPKTEDSSTSESSSQSDSSSDKTSPSSSSSSASGNDGSSSKTPDTSASASN

Nucleotide


Download         Length: 1875 bp        

>NTDB_id=1120034 EL079_RS05430 WP_018543640.1 1115107..1116981(-) (stkP) [Streptococcus anginosus strain NCTC10713]
ATGATTCAAGTCGGCAAGATATTTGCCGGACGATATAAAATCATCAAACAAATTGGTCGAGGTGGCATGGCAGATGTTTA
CTTGGCCAAAGATTTGATTTTAGACGGGGAAGAAGTCGCGGTTAAAGTTCTAAGAACGAATTATCAGACGGATCCGATTG
CTGTGGCGCGTTTTCAAAGAGAGGCGCGAGCTATGGCAGACTTGGATCATCCTCATATTGTTCGGATTACCGACATTGGA
GAAGAAGAAGGTCAGCAATATCTAGCAATGGAATATGTGGCTGGACTCGACTTAAAGCGCTATATCAAAGAGCATGCTCC
TTTGTCCAATGAAGAAGCGGTTCGAATCATGGGACAAATCCTTTTGGCGATGCGTTTGGCACACACGCACGGGATTGTTC
ACCGTGATTTGAAACCTCAAAATGTCCTTTTAACTCCAGATGGCGATGCAAAAGTCACTGACTTTGGAATTGCGGTAGCT
TTTGCAGAAACGAGCTTAACGCAAACCAACTCTATGCTGGGGTCTGTACATTATTTGTCACCAGAACAGGCGCGTGGTTC
AAAAGCGACCGTTCAGAGCGATATTTATGCCATGGGGATTATTTTCTATGAAATGCTGACAGGACATATCCCTTATGATG
GAGATAGTGCTGTTACGATTGCCCTACAGCATTTCCAAAAGCCTCTTCCTTCTGTGATTGCTGAAAATCCAAACGTTCCA
CAAGCATTGGAAAATGTAGTCATCAAGGCAACGGCAAAAAAATTGACGGATCGTTATCAGTCAGTTGCAGAAATGTATGT
GGATTTATCAAGCTGCTTATCTGCTGACCGTCGAAATGAGAAAAAACTAGTTTTTGATGACACTGCTAAAGCAGACACAA
AGACACTGCCGAAAGTATCACAAAATACCTTGACTTCTGCGACGAAGTCAACACCTACTCCTACAAAAGAAGCAGTCAGT
AGTAAGCCTACGCCTAAGCCAAAAGCAAAAAAGAAGCGCCGTTTAAGAACGCGATATAAAGTTTTGTTATCAGCAGTGGT
TTTAGTCATCGCAGCTCTGGTGGCTTTAGTCTATTTGAGCCCGTCAAATGTAAAAATCCCAGATGTTACTGGAAAAACTA
TTGCCCAAGCACGTTCTGCAATCGAAACTGCAGGTTTGAAAGTTGGCAAGGAAAAAGACGAATACAGTGATTCTGTTAAA
AAAGATTCAGTTATTCGCACCAATCCAGAAGCGGGAACGCAACGTCGTGAGGGCAGTACGGTGGATCTGATTGTCTCAAA
AGGGACTAAAACTTTTATTATGGAAGATTATAAAGGTCAGAAAAGAGCAGATGCTATCAACAATCTGGTACAAAAATACA
AGGTTTCAAAAGGCTTAATTAAAACAGAAGAAGTTGAAAGTAGTGAGTATGCGGCAGGAACAGTTGTTGATCAAACACCA
GCAGCAGGCAGCACTTATGATTTGACTTCAAAGACACGTATTACGTTAAAAGTAGCGAAGTCCGTTTCAAGTGTCACGAT
GCCAAGCTATATCGGCTCAACCTATGAATTTGCTTATAATAATTTGACGGAAGTGATTGGTATTCAAGGTGCGAATATTG
AAAAACGTACGGTTACAACAGCTCCAGCGGGTACACAGGCAAATACGATTATCAGACAAACCCCAGAAGCTGGTCAGTCT
TTGAATTTGAAGAGTGATCGCATTGTCTTATATGTATATGAGCCAAAAACCGAAGATTCTTCAACATCTGAAAGTAGTTC
ACAATCTGATAGCAGCTCAGATAAAACTAGCCCATCCTCTAGCAGTTCGTCAGCTAGTGGTAATGATGGAAGCAGCTCAA
AAACACCAGACACAAGTGCTAGTGCAAGTAATTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(364-427)

PASTA domain (PASTA)

(505-573)

PASTA domain (PASTA)

(433-500)

Protein kinase domain (Pkinase)

(12-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

66.325

93.75

0.622
  stkP Streptococcus pneumoniae D39

65.983

93.75

0.619
  stkP Streptococcus pneumoniae R6

65.983

93.75

0.619
  stkP Streptococcus pneumoniae Rx1

65.812

93.75

0.617
  pknB Streptococcus mutans UA159

59.145

93.75

0.554
  stkP/pknB Streptococcus salivarius strain HSISS4

55.333

96.154

0.532

Multiple sequence alignment