Detailed information NTG1120025

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: EL079_RS04655
• Genome accession: NZ_LR134283
• Coordinates: 959518..960549 (-)
• Length: 343 a.a.
• NCBI ID: WP_018543438.1
• Uniprot ID: A0A3S4M1H1
• Organism: Streptococcus anginosus strain NCTC10713
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 954518..965549

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL079_RS04635	-	955327..955896 (-)	570	WP_080559883.1	LURP-one-related/scramblase family protein	-
EL079_RS04640 (NCTC10713_00971)	prsA	956034..956972 (-)	939	WP_003031860.1	peptidylprolyl isomerase PrsA	-
EL079_RS04645 (NCTC10713_00972)	-	957079..957762 (-)	684	WP_003031902.1	O-methyltransferase	-
EL079_RS04650 (NCTC10713_00973)	pepF	957764..959566 (-)	1803	WP_003031896.1	oligoendopeptidase F	Regulator
EL079_RS04655 (NCTC10713_00974)	coiA	959518..960549 (-)	1032	WP_018543438.1	competence protein CoiA	Machinery gene
EL079_RS04660 (NCTC10713_00975)	-	960846..962015 (-)	1170	WP_003031874.1	MFS transporter	-
EL079_RS04665 (NCTC10713_00976)	-	962093..963469 (-)	1377	WP_003031862.1	DUF1958 domain-containing protein	-
EL079_RS04670 (NCTC10713_00977)	-	963586..964293 (-)	708	WP_003031845.1	glucosamine-6-phosphate deaminase	-

Sequence

Protein

• Length: 343 a.a.
• Molecular weight: 40787.09 Da
• Isoelectric Point: 9.4399

>NTDB_id=1120025 EL079_RS04655 WP_018543438.1 959518..960549(-) (coiA) [Streptococcus anginosus strain NCTC10713]
MLMACQENGKMLNAVEDRVNPPGRFLCPACKEAVRFKNGKVMRPHFAHISLKECHFYTENESAEHLNLKAALFTWARKSN
HAIQVEAYLPELQQIADLLVEKQIVLEVQCSSLSQKRLKERTESYRQHGYRVLWLLGKKLWLKNTLTNLQKDFLYFSQNM
GFHMWELDEQKQLLRLKYLIHEDLHGKVQYKEKSFAFGKGNLLDIFRQPFCKQEMTSFLAKEDKNICSYVRQQLYYQQPK
WMKWQAELYQTGDNLLTKTASDFYPQVQPVRSSSFCQIFQDLTPYYQQFSAYYEKEKNKNLQILYPPAFYAKIFGNIYDR
IGRTEEILWQNKEMKLKKNTLGT

Nucleotide

• Length: 1032 bp

>NTDB_id=1120025 EL079_RS04655 WP_018543438.1 959518..960549(-) (coiA) [Streptococcus anginosus strain NCTC10713]
ATGTTAATGGCTTGTCAGGAAAACGGAAAAATGCTAAATGCTGTGGAAGATAGGGTAAATCCACCGGGTAGGTTTCTCTG
CCCGGCTTGTAAGGAAGCGGTGCGATTTAAAAATGGCAAGGTGATGCGACCGCATTTTGCTCATATTTCTTTAAAAGAAT
GTCATTTTTATACGGAAAATGAAAGCGCAGAACACTTGAATTTGAAAGCTGCTTTGTTTACTTGGGCTAGAAAATCCAAT
CATGCGATTCAAGTAGAAGCTTATTTACCAGAATTGCAGCAAATCGCAGATTTGTTAGTTGAAAAACAAATTGTGCTTGA
AGTTCAGTGTAGCTCACTTAGTCAAAAACGCTTAAAAGAGCGTACGGAAAGTTATCGTCAGCATGGCTATCGCGTTCTTT
GGCTCTTGGGAAAGAAACTTTGGCTGAAAAATACTTTGACCAATTTACAAAAGGATTTTCTCTATTTCAGTCAAAATATG
GGCTTTCATATGTGGGAATTGGACGAACAAAAACAGCTTTTGAGGCTTAAATACTTGATTCATGAAGATTTGCATGGCAA
GGTTCAGTATAAGGAGAAAAGTTTTGCTTTTGGTAAAGGAAACCTTTTAGACATCTTTCGTCAGCCATTCTGCAAGCAGG
AAATGACGAGTTTTCTGGCAAAAGAAGATAAAAATATTTGCAGTTATGTGCGCCAGCAGCTCTACTATCAGCAGCCCAAA
TGGATGAAATGGCAGGCAGAATTGTATCAAACGGGTGATAATTTATTAACCAAAACGGCTAGTGACTTTTATCCGCAAGT
CCAACCTGTTCGTTCCAGCTCTTTCTGTCAGATTTTTCAGGATCTCACGCCTTATTACCAGCAATTTTCAGCTTATTATG
AAAAAGAAAAAAATAAAAATCTTCAAATTCTCTATCCTCCAGCCTTTTATGCAAAGATTTTTGGCAATATTTATGATAGA
ATAGGAAGGACGGAGGAAATTTTATGGCAAAACAAAGAAATGAAATTGAAGAAAAATACACTTGGGACCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (1-249)

3D structure

• AlphaFold DB: A0A3S4M1H1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus mitis NCTC 12261	53.503	91.545	0.49
coiA	Streptococcus pneumoniae Rx1	53.185	91.545	0.487
coiA	Streptococcus pneumoniae D39	53.185	91.545	0.487
coiA	Streptococcus pneumoniae R6	53.185	91.545	0.487
coiA	Streptococcus pneumoniae TIGR4	52.866	91.545	0.484
coiA	Lactococcus lactis subsp. cremoris KW2	45.062	94.461	0.426