Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   EL076_RS06995 Genome accession   NZ_LR134275
Coordinates   1402213..1404081 (-) Length   622 a.a.
NCBI ID   WP_126429838.1    Uniprot ID   -
Organism   Streptococcus vestibularis strain NCTC12167     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1397213..1409081
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL076_RS06960 (NCTC12167_01371) rimM 1397623..1398141 (-) 519 WP_126429836.1 ribosome maturation factor RimM -
  EL076_RS06975 (NCTC12167_01374) - 1398817..1399461 (-) 645 WP_003094523.1 response regulator transcription factor -
  EL076_RS06980 (NCTC12167_01375) - 1399451..1400461 (-) 1011 WP_048788123.1 sensor histidine kinase -
  EL076_RS06985 (NCTC12167_01376) liaF 1400458..1401156 (-) 699 WP_003096617.1 cell wall-active antibiotics response protein LiaF -
  EL076_RS10340 (NCTC12167_01377) - 1401310..1401759 (-) 450 WP_232009625.1 potassium channel family protein -
  EL076_RS06995 (NCTC12167_01378) stkP/pknB 1402213..1404081 (-) 1869 WP_126429838.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  EL076_RS07000 (NCTC12167_01379) - 1404081..1404818 (-) 738 WP_126429840.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  EL076_RS07005 (NCTC12167_01380) rsmB 1404862..1406184 (-) 1323 WP_126429842.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  EL076_RS07010 (NCTC12167_01381) fmt 1406174..1407109 (-) 936 WP_126429845.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 622 a.a.        Molecular weight: 67875.62 Da        Isoelectric Point: 6.4574

>NTDB_id=1119896 EL076_RS06995 WP_126429838.1 1402213..1404081(-) (stkP/pknB) [Streptococcus vestibularis strain NCTC12167]
MIQVGKLFAGRYRILKSIGRGGMADVYLANDLILDNESVAIKVLRTNYQTDQVAVARFQREARAMAELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKRFIQDHAPLSNQDVVRIMGEVLSAMTLAHQKGIIHRDLKPQNVLLTKDGRAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPFDGDSAVTIALQHFQKPLPSILAENRNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLHPSHSRDSKVVFDDMMDTKTLPKVDSVPSVGPEKKVSPKPSEPTPAP
SKQPREKASLAKKKKNLFSTLLKVFLGLVFIGIIIFAYLVFTNPDNVQVPNVVGQELSTAQTKLESAGFKVGDVNEVEND
SVDKGKVIKTDPTAGTTRKEGTSIDVYVSSGSKGFTLKNYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDDAKEGEILS
QSPEKNKSFNPKDSKAKIKFRVATPKTITMPDVTGLTVSTAVQTLNRKDISSSSIEYHDYNTGVKLDKSKVPSNTEVLYQ
DPQVGTAVDSAVILYISVVTESSSVQQSSSASTTHSSSSTSSSSESTASSTETATEATHTEQ

Nucleotide


Download         Length: 1869 bp        

>NTDB_id=1119896 EL076_RS06995 WP_126429838.1 1402213..1404081(-) (stkP/pknB) [Streptococcus vestibularis strain NCTC12167]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAGTCTATCGGACGTGGTGGTATGGCGGATGTTTA
TCTGGCTAACGACCTGATTCTGGATAATGAAAGTGTAGCTATTAAGGTGCTACGTACCAATTATCAAACTGATCAGGTTG
CTGTGGCGCGTTTCCAGCGTGAAGCGCGTGCCATGGCTGAGCTTAGCCATCCGAATATCGTTGCGATTCGAGATATTGGT
GAAGAAGACGGTCAGCAGTTCTTGGTGATGGAGTATGTGGACGGTTCGGACTTGAAGAGATTCATTCAAGACCATGCTCC
GTTGTCTAACCAAGATGTTGTGCGTATTATGGGGGAAGTCCTTTCCGCCATGACTCTTGCCCACCAAAAGGGCATTATTC
ACCGTGACCTTAAGCCACAGAATGTTCTATTAACTAAGGATGGTAGAGCTAAGGTTACAGACTTTGGTATCGCAGTAGCA
TTTGCTGAAACCAGTCTGACACAAACTAACTCAATGTTGGGGTCAGTCCATTATTTGTCACCAGAACAGGCACGTGGTTC
TAAAGCAACTATCCAAAGTGATATCTATGCTATGGGGATTATGCTCTTTGAAATGTTGACAGGGCATATTCCTTTTGATG
GCGATAGTGCAGTAACCATTGCACTTCAACATTTCCAAAAGCCCCTGCCATCGATTTTGGCTGAGAACCGTAATGTTCCT
CAAGCGTTAGAAAATGTTGTTATTAGAGCAACTGCTAAAAAGCTTGAAAATCGTTACAATAGCACTTTGGAAATGAGTCG
CGACCTAGTAACTAGTTTACATCCTAGTCATAGTCGTGATTCTAAAGTAGTTTTTGATGACATGATGGATACTAAGACCC
TGCCAAAGGTTGATTCAGTTCCATCAGTAGGTCCTGAGAAAAAGGTTTCTCCTAAACCATCAGAGCCAACACCGGCTCCA
AGCAAACAACCGAGGGAAAAAGCTTCTCTAGCTAAAAAGAAGAAAAATCTCTTTTCAACTCTACTCAAGGTTTTCCTAGG
CTTAGTCTTTATAGGAATTATCATTTTTGCCTATCTTGTTTTTACCAATCCTGACAATGTTCAGGTGCCAAATGTTGTAG
GTCAAGAGTTGTCAACAGCTCAGACGAAACTTGAAAGTGCAGGCTTTAAAGTTGGCGATGTTAATGAAGTCGAGAATGAT
TCAGTCGATAAGGGCAAAGTTATCAAGACCGACCCTACAGCTGGGACAACGCGTAAAGAGGGAACAAGCATTGATGTCTA
TGTTTCTTCTGGTAGCAAAGGTTTCACTCTGAAAAATTACAAGGGGAAAAATTATAAGGATGCCATTGAGGATTTAACTT
CGAATTATGGGGTTTCCGAGGATCAAATTGATATTCAACATGTTGAAGACGATGATGCTAAAGAAGGTGAAATCCTATCT
CAAAGTCCGGAGAAAAACAAGTCCTTCAATCCTAAAGATAGTAAGGCAAAAATCAAGTTCCGTGTGGCAACTCCTAAGAC
CATAACTATGCCTGATGTGACTGGTTTAACTGTCTCGACAGCAGTCCAAACCTTGAATCGTAAAGATATTTCAAGTAGTA
GTATTGAGTATCACGACTATAATACTGGTGTTAAGTTGGATAAGAGTAAGGTACCTAGTAATACAGAGGTACTTTATCAA
GACCCACAAGTTGGTACTGCCGTTGATAGCGCAGTGATTCTCTATATTTCAGTTGTAACTGAGAGTTCAAGCGTTCAACA
GTCAAGCTCAGCAAGTACGACACATTCGTCGTCATCTACAAGTTCTAGTTCTGAAAGTACAGCCTCTAGTACCGAAACAG
CTACTGAAGCTACCCACACAGAGCAATAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-235)

PASTA domain (PASTA)

(367-429)

PASTA domain (PASTA)

(508-577)

PASTA domain (PASTA)

(436-502)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

91.222

93.408

0.852
  pknB Streptococcus mutans UA159

60.778

99.196

0.603
  stkP Streptococcus pneumoniae TIGR4

58.907

79.421

0.468
  stkP Streptococcus pneumoniae D39

58.704

79.421

0.466
  stkP Streptococcus pneumoniae R6

58.704

79.421

0.466
  stkP Streptococcus pneumoniae Rx1

58.502

79.421

0.465

Multiple sequence alignment