Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   EL076_RS04380 Genome accession   NZ_LR134275
Coordinates   857947..858690 (-) Length   247 a.a.
NCBI ID   WP_126429389.1    Uniprot ID   -
Organism   Streptococcus vestibularis strain NCTC12167     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 857947..866359 857947..858690 within 0


Gene organization within MGE regions


Location: 857947..866359
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL076_RS04380 (NCTC12167_00873) comE/blpR 857947..858690 (-) 744 WP_126429389.1 response regulator transcription factor Regulator
  EL076_RS04390 (NCTC12167_00875) - 859689..860015 (-) 327 WP_064519801.1 helix-turn-helix domain-containing protein -
  EL076_RS04395 (NCTC12167_00876) - 860176..863172 (+) 2997 WP_064519799.1 SEC10/PgrA surface exclusion domain-containing protein -
  EL076_RS04400 (NCTC12167_00877) - 863299..863661 (+) 363 WP_064519797.1 hypothetical protein -
  EL076_RS04405 (NCTC12167_00878) - 863802..865070 (+) 1269 WP_232009677.1 DUF6287 domain-containing protein -
  EL076_RS04410 (NCTC12167_00879) - 865564..865947 (+) 384 WP_126429393.1 hypothetical protein -
  EL076_RS10240 (NCTC12167_00880) - 865973..866359 (+) 387 WP_232009680.1 hypothetical protein -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28747.15 Da        Isoelectric Point: 5.9898

>NTDB_id=1119888 EL076_RS04380 WP_126429389.1 857947..858690(-) (comE/blpR) [Streptococcus vestibularis strain NCTC12167]
MLNIFILEDEFLQQTRIETVIKDVIAKKSLKCKGPEIFGKPSQLLDAITERGSHQLFFLDIEIKGEEKKGLDIAKEIRKK
DPNATIVFVTTHSEFMPVTFKYRVAALDFIDKAMDDEDFYERVHLAIEYTMDKMGATIAQDSFTFETATAQVQVPFNNIL
FFETSPTIHKVILHTKEERMEFYASISEVERADDRLYRCHRSFIVNPENIVRINKEEKMVMFENNNECPISRTKYKGLLE
KVKSLKS

Nucleotide


Download         Length: 744 bp        

>NTDB_id=1119888 EL076_RS04380 WP_126429389.1 857947..858690(-) (comE/blpR) [Streptococcus vestibularis strain NCTC12167]
TTGTTAAATATTTTTATTTTAGAAGACGAATTTTTACAACAAACACGAATAGAGACCGTTATTAAGGATGTTATTGCAAA
AAAATCTCTAAAATGTAAAGGACCTGAGATTTTTGGAAAACCTAGCCAGCTACTTGACGCAATTACCGAAAGAGGTTCTC
ATCAACTTTTCTTTTTAGATATTGAAATTAAAGGAGAAGAAAAAAAGGGGCTAGACATTGCAAAAGAAATTCGGAAAAAA
GACCCTAATGCAACAATTGTTTTTGTAACAACACACTCAGAATTTATGCCAGTCACTTTTAAATATAGAGTTGCTGCACT
AGATTTTATTGATAAAGCTATGGATGATGAAGATTTTTATGAACGTGTTCATTTAGCAATTGAATATACCATGGATAAAA
TGGGTGCCACTATTGCCCAAGATTCTTTTACTTTTGAAACAGCTACGGCCCAAGTTCAAGTGCCTTTTAACAATATCTTA
TTTTTTGAAACATCTCCAACAATACATAAAGTTATTTTGCATACTAAAGAAGAACGCATGGAGTTCTACGCCAGTATTTC
AGAAGTTGAACGAGCTGATGATCGCCTATATCGATGCCATCGTTCATTTATCGTTAATCCTGAAAATATCGTTAGGATCA
ATAAGGAAGAGAAAATGGTAATGTTTGAAAATAATAATGAATGTCCCATTTCACGTACGAAATATAAGGGACTCCTAGAA
AAAGTTAAATCTTTGAAAAGCTAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(152-241)

Response regulator receiver domain (Response_reg)

(4-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.942

97.571

0.526
  comE/comE1 Streptococcus equinus JB1

46.091

98.381

0.453
  comE/comE2 Streptococcus equinus JB1

39.837

99.595

0.397
  comE/comE2 Streptococcus gordonii strain NCTC7865

37.247

100

0.372
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

37.247

100

0.372

Multiple sequence alignment