Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   EL076_RS04105 Genome accession   NZ_LR134275
Coordinates   805107..806522 (+) Length   471 a.a.
NCBI ID   WP_126429356.1    Uniprot ID   A0AAW7QG64
Organism   Streptococcus vestibularis strain NCTC12167     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 800107..811522
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL076_RS04080 (NCTC12167_00810) - 800579..801151 (-) 573 WP_126429352.1 ECF transporter S component -
  EL076_RS04085 (NCTC12167_00811) coaC 801144..801707 (-) 564 WP_126429354.1 phosphopantothenoylcysteine decarboxylase -
  EL076_RS04090 (NCTC12167_00812) - 801700..802383 (-) 684 WP_003094310.1 phosphopantothenate--cysteine ligase -
  EL076_RS04095 (NCTC12167_00813) - 802578..804248 (+) 1671 WP_003094109.1 formate--tetrahydrofolate ligase -
  EL076_RS04100 (NCTC12167_00814) ciaR 804443..805117 (+) 675 WP_003093839.1 response regulator transcription factor Regulator
  EL076_RS04105 (NCTC12167_00815) ciaH 805107..806522 (+) 1416 WP_126429356.1 cell wall metabolism sensor histidine kinase WalK Regulator
  EL076_RS04110 (NCTC12167_00816) rpsT 806609..806845 (-) 237 WP_003093369.1 30S ribosomal protein S20 -
  EL076_RS04115 (NCTC12167_00817) coaA 806914..807834 (-) 921 WP_037621505.1 type I pantothenate kinase -
  EL076_RS04120 (NCTC12167_00818) - 807945..808535 (+) 591 WP_003093879.1 class I SAM-dependent methyltransferase -
  EL076_RS04125 (NCTC12167_00819) - 808532..809809 (+) 1278 WP_003097398.1 pyrimidine-nucleoside phosphorylase -
  EL076_RS04130 (NCTC12167_00820) deoC 809843..810505 (+) 663 WP_003094196.1 deoxyribose-phosphate aldolase -
  EL076_RS04135 (NCTC12167_00821) - 810492..810890 (+) 399 WP_003094441.1 cytidine deaminase -

Sequence

Protein


Download         Length: 471 a.a.        Molecular weight: 53384.94 Da        Isoelectric Point: 7.9614

>NTDB_id=1119886 EL076_RS04105 WP_126429356.1 805107..806522(+) (ciaH) [Streptococcus vestibularis strain NCTC12167]
MLTKCFNYLFRRIKSDGFKSFIHFFATFSGIFLIMTVMILQILSYGVYSNVDSSLKAAATKTNSYLEMEMLKREFFLTSE
VDQNNTTTIYQAYDTKSSTAETPDSSGSKKESKKKSKMEDAPHDLSVAANTSVLVLDKNGKVLNVVDKFSSLSNLPIDKN
NIDVISKGSAQNYFDQTENYRLITEKVDNNFYPDAKYLVIAINTTQLEEATERYVKLIVIMMSFFWLLSIAASLYLAKWS
RRPIQESLEKQKAFVENASHELRTPLAVIQNRLEALFRKPESTILDNSENIASSLDEVRNMRLLTTNLLNLARRDDGIKP
EIETLDSSFFDTVFTNYAMIAEESEKGFTAQNQVGRSIQTDKTLLKQLMTILFDNAIKYTEDDGQVTFTVRTNDRHLYIT
VADNGPGIADEDKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIVLALKGTIIVKDNQPKGTIFEVKITGV

Nucleotide


Download         Length: 1416 bp        

>NTDB_id=1119886 EL076_RS04105 WP_126429356.1 805107..806522(+) (ciaH) [Streptococcus vestibularis strain NCTC12167]
ATGCTGACTAAATGTTTCAATTATCTCTTCAGGAGAATCAAGTCAGACGGCTTTAAGTCCTTCATCCATTTCTTTGCAAC
TTTTTCTGGTATTTTCCTTATCATGACTGTTATGATTTTGCAGATTCTCAGTTATGGAGTTTATTCCAATGTTGACTCTA
GTCTGAAAGCAGCAGCAACTAAGACAAATTCTTATTTGGAAATGGAAATGCTAAAACGGGAATTTTTTCTGACTTCTGAG
GTGGATCAAAATAATACAACAACCATTTATCAGGCTTATGATACTAAAAGCTCTACAGCTGAAACACCTGACTCGAGTGG
CTCTAAGAAAGAATCTAAGAAGAAATCAAAGATGGAAGATGCCCCTCACGATTTATCAGTTGCAGCAAATACTAGTGTCC
TAGTGCTTGATAAAAATGGAAAAGTCCTCAATGTCGTTGATAAATTTTCAAGCTTATCTAATTTACCAATAGATAAAAAT
AATATTGATGTTATCAGTAAGGGAAGTGCTCAGAACTATTTTGATCAAACAGAAAATTATCGCTTGATTACTGAAAAAGT
AGATAATAATTTCTATCCTGATGCTAAGTACCTTGTTATTGCAATCAATACGACGCAATTAGAAGAAGCCACTGAACGTT
ATGTAAAACTAATTGTCATTATGATGAGTTTTTTTTGGCTACTATCTATCGCAGCTAGTTTGTATTTGGCAAAATGGTCA
AGACGGCCTATACAGGAAAGTCTGGAGAAGCAGAAGGCATTTGTTGAGAATGCTAGCCACGAGTTGCGTACGCCACTTGC
TGTGATTCAAAACCGACTAGAGGCGCTTTTCCGTAAGCCTGAAAGTACCATTTTAGATAATTCAGAAAACATTGCTTCAA
GTCTTGATGAAGTCCGAAATATGCGTCTTTTGACGACCAATCTCTTGAATTTGGCTCGTCGTGATGATGGTATTAAACCA
GAAATTGAAACCTTAGATTCTTCTTTCTTTGATACAGTCTTTACCAATTATGCTATGATTGCTGAAGAAAGTGAAAAGGG
GTTTACTGCTCAAAATCAGGTTGGGCGCTCAATCCAAACTGATAAGACTCTATTGAAGCAGCTCATGACAATTTTATTCG
ATAATGCTATCAAATATACAGAAGATGATGGCCAGGTGACTTTCACCGTTCGTACTAATGATCGTCATCTTTATATTACA
GTGGCAGACAATGGCCCTGGTATTGCAGATGAAGATAAGAAAAAAATCTTTGATCGTTTCTACCGAGTAGACAAAGCTAG
AACTAGACAAAAAGGTGGTTTTGGGTTGGGCTTATCTTTGGCACAACAGATTGTTCTTGCTCTTAAAGGAACGATAATTG
TCAAGGACAATCAGCCGAAGGGGACTATTTTTGAAGTTAAAATTACCGGAGTCTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(361-468)

His Kinase A (phospho-acceptor) domain (HisKA)

(252-317)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.087

97.665

0.548
  ciaH Streptococcus pneumoniae Rx1

50.108

98.726

0.495
  ciaH Streptococcus pneumoniae D39

50.108

98.726

0.495
  ciaH Streptococcus pneumoniae R6

50.108

98.726

0.495
  ciaH Streptococcus pneumoniae TIGR4

50.108

98.726

0.495

Multiple sequence alignment