Detailed information NTG1119885

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: EL076_RS04100
• Genome accession: NZ_LR134275
• Coordinates: 804443..805117 (+)
• Length: 224 a.a.
• NCBI ID: WP_003093839.1
• Uniprot ID: -
• Organism: Streptococcus vestibularis strain NCTC12167
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 799443..810117

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL076_RS04080 (NCTC12167_00810)	-	800579..801151 (-)	573	WP_126429352.1	ECF transporter S component	-
EL076_RS04085 (NCTC12167_00811)	coaC	801144..801707 (-)	564	WP_126429354.1	phosphopantothenoylcysteine decarboxylase	-
EL076_RS04090 (NCTC12167_00812)	-	801700..802383 (-)	684	WP_003094310.1	phosphopantothenate--cysteine ligase	-
EL076_RS04095 (NCTC12167_00813)	-	802578..804248 (+)	1671	WP_003094109.1	formate--tetrahydrofolate ligase	-
EL076_RS04100 (NCTC12167_00814)	ciaR	804443..805117 (+)	675	WP_003093839.1	response regulator transcription factor	Regulator
EL076_RS04105 (NCTC12167_00815)	ciaH	805107..806522 (+)	1416	WP_126429356.1	cell wall metabolism sensor histidine kinase WalK	Regulator
EL076_RS04110 (NCTC12167_00816)	rpsT	806609..806845 (-)	237	WP_003093369.1	30S ribosomal protein S20	-
EL076_RS04115 (NCTC12167_00817)	coaA	806914..807834 (-)	921	WP_037621505.1	type I pantothenate kinase	-
EL076_RS04120 (NCTC12167_00818)	-	807945..808535 (+)	591	WP_003093879.1	class I SAM-dependent methyltransferase	-
EL076_RS04125 (NCTC12167_00819)	-	808532..809809 (+)	1278	WP_003097398.1	pyrimidine-nucleoside phosphorylase	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25408.04 Da
• Isoelectric Point: 4.2405

>NTDB_id=1119885 EL076_RS04100 WP_003093839.1 804443..805117(+) (ciaR) [Streptococcus vestibularis strain NCTC12167]
MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGDEGLYEAESGVYDLILLDLMLPEKDGFTVLKELREQGITTPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFDQNTLSFGDVRVNLATNSTYVGDKEVELLGKEFDLLVY
FLQNQNVILPKSQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTDFATNLQTLRSVGYILKNAD

Nucleotide

• Length: 675 bp

>NTDB_id=1119885 EL076_RS04100 WP_003093839.1 804443..805117(+) (ciaR) [Streptococcus vestibularis strain NCTC12167]
ATGATTAAAATTTTACTAGTAGAAGATGATTTGAGTTTGTCAAACTCAGTTTTTGATTTTTTAGATGACTTTGCGGATGT
GATGCAAGTATTTGATGGAGATGAAGGTCTTTACGAAGCTGAAAGTGGTGTTTATGATTTGATTCTCTTGGACTTAATGT
TACCTGAAAAAGATGGTTTTACAGTTCTTAAAGAATTGCGAGAGCAAGGAATAACGACTCCTGTTCTTATCATGACTGCT
AAGGAAAGTCTAGACGATAAGGGGCATGGCTTCGAACTCGGAGCTGATGATTATCTAACCAAGCCTTTCTATTTAGAAGA
ATTGAAGATGCGTATTCAAGCACTTTTGAAACGTTCTGGTAAATTTGACCAAAATACTCTTTCTTTTGGAGATGTTCGTG
TCAATCTTGCTACAAATTCAACCTATGTAGGCGATAAAGAAGTAGAACTTCTTGGTAAAGAATTTGATTTATTGGTCTAC
TTCCTACAAAATCAAAACGTTATCTTGCCTAAGTCGCAAATTTTTGATCGTCTTTGGGGATTTGATAGTGACACTACTAT
CTCTGTTGTTGAAGTTTATGTTTCGAAAATTCGTAAGAAACTTAAGGGGACAGATTTTGCTACCAACCTACAGACCTTAA
GAAGTGTGGGGTATATTTTGAAGAATGCTGACTAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (146-220)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus pneumoniae Rx1	88.341	99.554	0.879
ciaR	Streptococcus pneumoniae D39	88.341	99.554	0.879
ciaR	Streptococcus pneumoniae R6	88.341	99.554	0.879
ciaR	Streptococcus pneumoniae TIGR4	88.341	99.554	0.879
ciaR	Streptococcus mutans UA159	87.5	100	0.875
covR	Lactococcus lactis subsp. lactis strain DGCC12653	37.333	100	0.375
vicR	Streptococcus mutans UA159	35.146	100	0.375
micA	Streptococcus pneumoniae Cp1015	34.322	100	0.362