Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EL076_RS01720 Genome accession   NZ_LR134275
Coordinates   312076..312765 (+) Length   229 a.a.
NCBI ID   WP_126428993.1    Uniprot ID   -
Organism   Streptococcus vestibularis strain NCTC12167     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 307076..317765
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL076_RS10180 (NCTC12167_00338) - 308039..308209 (+) 171 Protein_279 ascorbate 6-phosphate lactonase -
  EL076_RS01700 (NCTC12167_00339) - 308226..308897 (-) 672 WP_003092220.1 TrkA family potassium uptake protein -
  EL076_RS01705 (NCTC12167_00340) - 308937..310301 (-) 1365 WP_126428989.1 TrkH family potassium uptake protein -
  EL076_RS01710 (NCTC12167_00341) rsmG 310370..311083 (-) 714 WP_126428991.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  EL076_RS01715 (NCTC12167_00342) - 311382..311918 (+) 537 WP_064519554.1 DUF177 domain-containing protein -
  EL076_RS01720 (NCTC12167_00343) covR 312076..312765 (+) 690 WP_126428993.1 response regulator transcription factor Regulator
  EL076_RS01725 (NCTC12167_00344) covS 312762..314279 (+) 1518 WP_003092189.1 HAMP domain-containing histidine kinase Regulator
  EL076_RS01730 (NCTC12167_00345) nrdR 314401..314880 (+) 480 WP_003092257.1 transcriptional regulator NrdR -
  EL076_RS01735 (NCTC12167_00346) - 314877..316052 (+) 1176 WP_126428995.1 DnaD domain protein -
  EL076_RS01740 (NCTC12167_00347) dnaI 316056..316958 (+) 903 WP_126428997.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26570.62 Da        Isoelectric Point: 4.6958

>NTDB_id=1119872 EL076_RS01720 WP_126428993.1 312076..312765(+) (covR) [Streptococcus vestibularis strain NCTC12167]
MSKRILIVEDERNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKNTYIMMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARIRATFRRQDIEATKNAPAKASTYRDLKLDVQNRAVVRGDEAIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDVIETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1119872 EL076_RS01720 WP_126428993.1 312076..312765(+) (covR) [Streptococcus vestibularis strain NCTC12167]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAGAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
TGACGTTGTGACAGCAGACAACGGACGCGAAGGACTTGAAATGGCACTTGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTCGAAGTGACACGTCGTCTCCAACAAGAAAAAAATACTTATATTATGATGATGACA
GCTCGCGACTCAATCATGGATATTGTTGCCGGTTTGGACCGTGGAGCTGATGACTATATTGTAAAACCATTTGCGATTGA
AGAACTGTTGGCACGTATTCGTGCAACCTTCCGTCGCCAAGATATCGAAGCTACTAAGAATGCACCAGCTAAAGCGTCAA
CCTATCGCGATTTGAAATTGGATGTTCAAAACCGTGCAGTTGTTCGTGGTGATGAGGCGATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTAAGCAATATGAACCAAGTAATGACTCGTGAGGAACTCTTGCTTCAAGTCTGGAAATA
TGATGACGTAATTGAAACAAACGTTGTAGATGTTTATATTCGTTACTTACGTGGGAAAATCGACATTCCAGGTAAGGAAT
CATACATTCAAACAGTACGAGGGATGGGTTACGTTATCCGTGAAAAATGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

97.38

100

0.974
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.228

99.563

0.659
  vicR Streptococcus mutans UA159

44.828

100

0.454
  micA Streptococcus pneumoniae Cp1015

43.913

100

0.441

Multiple sequence alignment