Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   EL076_RS01725 Genome accession   NZ_LR134275
Coordinates   312762..314279 (+) Length   505 a.a.
NCBI ID   WP_003092189.1    Uniprot ID   -
Organism   Streptococcus vestibularis strain NCTC12167     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 307762..319279
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL076_RS10180 (NCTC12167_00338) - 308039..308209 (+) 171 Protein_279 ascorbate 6-phosphate lactonase -
  EL076_RS01700 (NCTC12167_00339) - 308226..308897 (-) 672 WP_003092220.1 TrkA family potassium uptake protein -
  EL076_RS01705 (NCTC12167_00340) - 308937..310301 (-) 1365 WP_126428989.1 TrkH family potassium uptake protein -
  EL076_RS01710 (NCTC12167_00341) rsmG 310370..311083 (-) 714 WP_126428991.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  EL076_RS01715 (NCTC12167_00342) - 311382..311918 (+) 537 WP_064519554.1 DUF177 domain-containing protein -
  EL076_RS01720 (NCTC12167_00343) covR 312076..312765 (+) 690 WP_126428993.1 response regulator transcription factor Regulator
  EL076_RS01725 (NCTC12167_00344) covS 312762..314279 (+) 1518 WP_003092189.1 HAMP domain-containing histidine kinase Regulator
  EL076_RS01730 (NCTC12167_00345) nrdR 314401..314880 (+) 480 WP_003092257.1 transcriptional regulator NrdR -
  EL076_RS01735 (NCTC12167_00346) - 314877..316052 (+) 1176 WP_126428995.1 DnaD domain protein -
  EL076_RS01740 (NCTC12167_00347) dnaI 316056..316958 (+) 903 WP_126428997.1 primosomal protein DnaI -
  EL076_RS01745 (NCTC12167_00348) der 317064..318374 (+) 1311 WP_003092252.1 ribosome biogenesis GTPase Der -
  EL076_RS01750 (NCTC12167_00349) - 318439..319086 (+) 648 WP_126428999.1 ribonuclease P -

Sequence

Protein


Download         Length: 505 a.a.        Molecular weight: 57503.73 Da        Isoelectric Point: 5.1762

>NTDB_id=1119873 EL076_RS01725 WP_003092189.1 312762..314279(+) (covS) [Streptococcus vestibularis strain NCTC12167]
MSKLFGKVTIRKKLTITAAVVFFIVLSMFTLVVVLSANTLLLQRERQNVNNTISKVVTYIEKDWDSDEELSPEPLLAALY
SPKDIYGSMINGVLSEKHSLDGQVAVSNKLYSNQSVYVYDKKGTFIFTSEEDTDSPPGMSEVNKLKSVSYKGKRGFLLQV
PIYGKDKKTIVGYAQVFHDLEFYYALKKRLIFLLIFLEVGITVLVIAVTVVVLTSILRPMRQLHETMGIITDSPSDLELR
SKIESHDEIGDLAVNFNRMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHEANRM
TIMINDMLDSIRVKGSFDNHRNDTCDLNSSIRTVIGNFRVLHEDYQFYLNDFESSERPAQIYSQHFEQVITILIDNAVKY
SPVNKEIQVTIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCHIDVSSE
LGVGTRFDLYIPFAGSETTTPQLED

Nucleotide


Download         Length: 1518 bp        

>NTDB_id=1119873 EL076_RS01725 WP_003092189.1 312762..314279(+) (covS) [Streptococcus vestibularis strain NCTC12167]
ATGAGTAAATTATTTGGTAAAGTAACTATTAGAAAAAAGTTGACCATAACAGCTGCTGTGGTCTTCTTTATTGTATTGTC
GATGTTCACTCTGGTTGTTGTTCTCTCAGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAAATAATACAATCT
CAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCTGATGAAGAGTTGAGTCCAGAACCGCTTTTAGCGGCCCTTTAT
TCACCGAAAGATATCTATGGATCAATGATTAATGGAGTGCTTTCTGAAAAGCATTCCTTAGATGGTCAAGTTGCGGTTTC
TAATAAATTATATTCCAATCAGTCTGTCTATGTTTATGACAAAAAGGGAACTTTTATCTTTACTTCTGAGGAGGATACAG
ACTCACCTCCAGGCATGTCTGAGGTCAATAAACTGAAGTCGGTTTCCTATAAAGGTAAACGTGGTTTCTTATTACAAGTT
CCAATCTATGGCAAGGATAAGAAGACCATTGTTGGGTATGCTCAAGTTTTCCATGATTTGGAATTCTACTATGCGTTAAA
AAAGCGTCTAATTTTTCTATTGATATTCCTTGAAGTAGGAATAACTGTCTTAGTTATTGCAGTAACTGTAGTTGTCTTGA
CATCTATTCTTCGTCCGATGAGGCAGTTGCACGAAACGATGGGTATTATTACAGATTCGCCAAGTGACTTGGAGCTTCGT
TCTAAGATTGAGAGTCATGATGAGATTGGTGATTTGGCGGTTAACTTTAACCGTATGATGGATAAAATTCAAGAAAATAA
TCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCACGAATTACGTACTCCAATTGCAGTTATTAAGGGACATATGGACC
TCTTGCAACGTTGGGGTAAAAATGATCCTGAAATCCTTGAAGAAAGTCTTGAAGCTGCAAGTCACGAAGCCAACCGTATG
ACGATTATGATTAACGATATGTTGGATTCTATTCGTGTTAAAGGGTCATTTGACAATCATAGAAATGATACATGTGATTT
GAATTCTTCAATCCGTACGGTTATTGGGAATTTCCGTGTCCTACATGAAGACTACCAATTCTATCTCAATGATTTTGAGA
GTTCAGAGCGTCCGGCACAGATTTACAGCCAGCATTTTGAACAGGTTATTACTATTTTGATTGATAATGCAGTCAAGTAT
TCGCCTGTTAATAAGGAAATCCAGGTTACTATCAAGGCTCTGGAAGATGAGATGTTAGTACAGGTACAGGATAATGGTGA
GGGTATCTCCAAAGAAGATATTGAACATATCTTTGAACGCTTCTATCGTTCAGATAAGGCGCGTAACCGTACGACAACCC
AATCTGGTGTGGGTATTGGCTTATCAATCCTCTATCAAATTGTGGAAGCTTATCGATGCCATATTGATGTCAGTTCAGAA
CTTGGTGTGGGTACACGTTTTGACCTCTACATTCCTTTTGCAGGGTCAGAAACTACGACACCTCAACTTGAGGATTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(270-329)

HAMP domain (HAMP)

(213-265)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(384-493)

ArlS sensor domain (ArlS_N)

(39-188)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

95.817

99.406

0.952

Multiple sequence alignment